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01-08-2020 | Review Article | bijlage 1/2020 Open Access

Netherlands Heart Journal 1/2020

Ischaemia with no obstructive coronary arteries

Netherlands Heart Journal > bijlage 1/2020
R. E. Konst, J. G. Meeder, M. E. Wittekoek, A. H. E. M. Maas, Y. Appelman, J. J. Piek, T. P. van de Hoef, P. Damman, S. E. Elias-Smale


Ischaemia with no obstructive coronary arteries (INOCA) is a common ischaemic heart disease with a female preponderance, mostly due to underlying coronary vascular dysfunction comprising coronary microvascular dysfunction and/or epicardial coronary vasospasm. Since standard ischaemia detection tests and coronary angiograms are not suitable to diagnose coronary vascular dysfunction, INOCA is often overlooked in current cardiology practice. Future research, including large outcome trials, is much awaited. Yet, adequate diagnosis is possible and treatment options are available and vital to reduce symptoms and most probably improve cardiovascular prognosis. This review intends to give a brief overview of the clinical presentation, underlying pathophysiology, and the diagnostic and treatment options in patients with suspected INOCA.

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Netherlands Heart Journal

Het Netherlands Heart Journal wordt uitgegeven in samenwerking met de Nederlandse Vereniging voor Cardiologie en de Nederlandse Hartstichting. Het tijdschrift is Engelstalig en wordt gratis beschikbaa ...

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