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The online version of this article (https://doi.org/10.1007/s11136-018-1932-2) contains supplementary material, which is available to authorized users.
Few studies focus on the health-related quality of life (HRQoL) of preschool children with overweight or obesity. This is relevant for evaluation of obesity prevention trials using a quality-adjusted life year (QALY) framework. This study examined the association between weight status in the preschool years and HRQoL at age 5 years, using a preference-based instrument.
HRQoL [based on parent proxy version of the Health Utilities Index Mark 3 (HUI3)] and weight status were measured in children born in Australia between 2007 and 2009. Children’s health status was scored across eight attributes of the HUI3—vision, hearing, speech, ambulation, dexterity, emotion, cognition and pain, and these were used to calculate a multi-attribute utility score. Ordinary least squares (OLS), Tobit and two-part regressions were used to model the association between weight status and multi-attribute utility.
Of the 368 children for whom weight status and HUI3 data were available, around 40% had overweight/obesity. After adjusting for child’s sex, maternal education, marital status and household income, no significant association between weight status in the preschool years and multi-attribute utility scores at 5 years was found.
Alternative approaches for capturing the effects of weight status in the preschool years on preference-based HRQoL outcomes should be tested. The application of the QALY framework to economic evaluations of obesity-related interventions in young children should also consider longitudinal effects over the life-course.
Clinical Trial Registration The Healthy Beginnings Trial was registered with the Australian Clinical Trial Registry (ACTRNO12607000168459).
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Supplementary material 1 (PDF 107 KB)11136_2018_1932_MOESM1_ESM.pdf
NCD Risk Factor Collaboration. (2017). Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: A pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults. Lancet, 390, 2627–2642. CrossRef
World Health Organization. (2016). Report of the commission on ending childhood obesity. Geneva: World Health Organization.
Stettler, N., & Iotova, V. (2010). Early growth patterns and long-term obesity risk. Current Opinion in Clinical Nutrition & Metabolic Care, 13, 294–299. CrossRef
Döring, N., Mayer, S., Rasmussen, F., & Sonntag, D. (2016). Economic evaluation of obesity prevention in early childhood: Methods, limitations and recommendations. International Journal of Environmental Research and Public Health, 13, 1–11. CrossRef
Trevino, R. P., Pham, T. H., & Edelstein, S. L. (2013). Obesity and preference-weighted quality of life of ethnically diverse middle school children: The HEALTHY study. Journal of Obesity, 2013, 1–8. CrossRef
Wen, L. M., Baur, L. A., Simpson, J. M., Rissel, C., Wardle, K., & Flood, V. M. (2012). Effectiveness of home based early intervention on children’s BMI at age 2: Randomised controlled trial. BMJ, 344, 1–11. CrossRef
NSW Department of Health. (2007). 2006 Report on adult health from the New South Wales population health survey. Sydney: Centre for Epidemiology and Research.
World Health Organization. (2011). WHO AnthroPlus for Personal Computers, Version 3.2.2, 2011: Software for assessing growth and development of the world’s children. WHO: Geneva. Retrieved June 1, 2011, from http://www.who.int/childgrowth/software/en/.
World Health Organization. (2015). Growth reference data for 5–19 years. Retrieved December 1, 2015, from http://www.who.int/childgrowth/en/.
Horsman, J., Furlong, W., Feeny, D., & Torrance, G. (2003). The Health Utilities Index (HUI®): Concepts, measurement properties and applications. Health and Quality of Life Outcomes, 1, 1–29. CrossRef
Tobin, J. (1958). Estimation of relationships for limited dependent variables. Econometrica, 26, 24–36. CrossRef
StataCorp. (2016). Stata Statistic Software: Release 14.2, 2016. Texas: StataCorp LLC.
Thorrington, D., & Eames, K. (2015). Measuring health utilities in children and adolescents: A systematic review of the literature. PLoS ONE, 10, 1–21. CrossRef
- Is there an association between early weight status and utility-based health-related quality of life in young children?
Eng Joo Tan
Marjory L. Moodie
Li Ming Wen
Louise A. Baur
Alison J. Hayes
- Springer International Publishing
- Quality of Life Research
An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation - Official Journal of the International Society of Quality of Life Research
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649