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01-03-2013 | Original Paper | Uitgave 3/2013

Is Infertility Associated with Childhood Autism?

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 3/2013

Auteurs:: Judith K. Grether, Yinge Qian, Mary S. Croughan, Yvonne W. Wu, Michael Schembri, Loretta Camarano, Lisa A. Croen

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Abstract

Concerns persist about a possible link between infertility and risk of autism spectrum disorders (ASD). Interpretation of existing studies is limited by racial/ethnic homogeneity of study populations and other factors. Using a case–control design, we evaluated infertility history and treatment documented in medical records of members of Kaiser Permanente Northern California. Among singletons (349 cases, 1,847 controls), we found no evidence to support an increase in risk of ASD associated with infertility. Among multiple births (21 cases, 54 controls), we found an increased risk associated with infertility history and with infertility evaluations and treatment around the time of index pregnancy conception; however, small sample size and lack of detailed data on treatments preclude firm interpretation of results for multiple births.

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Titel: Is Infertility Associated with Childhood Autism?
Auteurs:: Judith K. Grether
Yinge Qian
Mary S. Croughan
Yvonne W. Wu
Michael Schembri
Loretta Camarano
Lisa A. Croen
Publicatiedatum: 01-03-2013
DOI: https://doi.org/10.1007/s10803-012-1598-5
Uitgeverij: Springer US
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 3/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

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