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Concerns persist about a possible link between infertility and risk of autism spectrum disorders (ASD). Interpretation of existing studies is limited by racial/ethnic homogeneity of study populations and other factors. Using a case–control design, we evaluated infertility history and treatment documented in medical records of members of Kaiser Permanente Northern California. Among singletons (349 cases, 1,847 controls), we found no evidence to support an increase in risk of ASD associated with infertility. Among multiple births (21 cases, 54 controls), we found an increased risk associated with infertility history and with infertility evaluations and treatment around the time of index pregnancy conception; however, small sample size and lack of detailed data on treatments preclude firm interpretation of results for multiple births.
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Croen, L. A., Matevia, M., Yoshida, C. K., & Grether, J. K. (2008). Maternal Rh D status, anti-D immune globulin exposure during pregnancy, and risk of autism spectrum disorders. American Journal of Obstetrics and Gynecology, 199(3), 234.e1–234.e6. Epub 2008 Jun 13.
Durkin, M. S., Maenner, M. J., Newschaffer, C. J., Lee, L. C., Cunniff, C. M., Daniels, J. L., et al. (2008). Advanced parental age and the risk of autism spectrum disorder. American Journal of Epidemiology, 168(11), 1268–1276. Epub 2008 Oct. 21.
Giudice, E., Crisci, C., Eshkol, A., & Papoian, R. (1994). Composition of commercial gonadotrophin preparations extracted from human post-menopausal urine: Characterization of non-gonadotrophin proteins. Human Reproduction, 9(12), 2291–2299. PubMed
Grether, J. K., Anderson, M. C., Croen, L. A., Smith, D., & Windham, G. C. (2009). Risk of autism and increasing maternal and paternal age in a large north American population. American Journal of Epidemiology, 170(9), 1118–1126. Epub 2009 Sep 25.
Hallmayer, J., Cleveland, S., Torres, A., Phillips, J., Cohen, B., Torigoe, T., et al. (2011). Genetic heritability and shared environmental factors among twin pairs with autism. Archives of General Psychiatry, 68(11), 1095–1102. doi: 10.1001/archgenpsychiatry.2011.76. Epub 2011 Jul 4.
Hvidtjorn, D., Grove, J., Schendel, D., Schieve, L. A., Svaerke, C., Ernst, E., et al. (2010). Risk of autism spectrum disorders in children born after assisted conception: A population-based follow-up study. Journal of Epidemiology and Community Health, 65(6), 497–502. Epub 2010 Jun 27.
Hvidtjorn, D., Schieve, L., Schendel, D., Jacobsson, B., Svaerke, C., & Thorsen, P. (2009). Cerebral palsy, autism spectrum disorders, and developmental delay in children born after assisted conception. Archives of Pediatrics and Adolescent Medicine, 163, 72–83.
Klemetti, R., Sevin, T., Gissler, M., & Hemminki, E. (2006). Health of children born as a result of in vitro fertilization. Pediatrics, 119(5), 1819–1827. CrossRef
Leslie, G. I. (2004). Mental development of children conceived using intracytoplasmic sperm injection. The current evidence. Minerva Ginecologica, 56(3), 247–257. Review.
Maimburg, R. D., & Vaeth, M. (2007). Do Children born after assisted conception have less risk of developing infantile autism? Human Reproduction, 22, 1841–1843.
Pinborg, A., Loft, A., Schmidt, L., Greisen, G., Rasmussen, S., Andersen, A. N. (2004). Neurological sequelae in twins born after assisted conception: Controlled national cohort study. BMJ, 329(7461):311. Epub 2004 Jul 15.
Reichenberg, A., Gross, R., Sandin, S., & Susser, E. S. (2010). Advancing paternal and maternal age are both important for autism risk. American Journal of Public Health, 100(5), 772–773; author reply 773. Epub 2010 Mar 18.
Ronald, A., & Hoekstra, R. A. (2011). Autism spectrum disorders and autistic traits: A decade of new twin studies. American Journal of Medical Genetics Part B, 156, 255–274. CrossRef
Schieve, L. A., Rasmussen, S. A., Buck, G. M., Schendel, D. E., Reynolds, M. A., & Wright, V. C. (2004). Are children born after assisted reproductive technology at increased risk for adverse health outcomes? Obstetrics & Gynecology, 103(6), 1154–1163. Review.
Wu, Y. W., Croen, L. A., Henning, L., Najjar, D. V., Schembri, M., & Croughan, M. S. (2006). Potential association between infertility and spinal neural tube defects in offspring. Birth Defects Research, Part A: Clinical and Molecular Teratology, 76(10), 718–722. CrossRef
- Is Infertility Associated with Childhood Autism?
Judith K. Grether
Mary S. Croughan
Yvonne W. Wu
Lisa A. Croen
- Springer US