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02-11-2022

Investigating gender-based differential item functioning on the Kansas City Cardiomyopathy Questionnaire (KCCQ) using qualitative content analysis

Auteurs: Theresa M. Coles, Nicole Lucas, Molly McFatrich, Debra Henke, Jennifer L. Ridgeway, Emma M. Behnken, Kevin Weinfurt, Bryce B. Reeve, Amy Corneli, Shannon M. Dunlay, John A. Spertus, Li Lin, Ileana L. Piña, Fraser D. Bocell, Michelle E. Tarver, Heidi Dohse, Anindita Saha, Brittany Caldwell

Gepubliceerd in: Quality of Life Research | Uitgave 3/2023

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Abstract

Purpose

The purpose of this study is to evaluate potential gender-based differences in interpreting the Kansas City Cardiomyopathy Questionnaire (KCCQ-23) and to explore if there are aspects of health-related quality of life (HRQOL) not captured by the KCCQ-23 that are important to assess in men and/or women with heart failure (HF).

Methods

Patients ≥ 22 years of age with clinician-diagnosed HF and left ventricular ejection fraction ≤ 40% were recruited from two academic medical centers to participate in semi-structured concept elicitation and cognitive debriefing interviews. Enrollment was stratified by patient-identified gender (half women/half men). All interviews were conducted over the phone/web and audio recorded. Interviews were transcribed and descriptive qualitative content analysis was used to summarize findings overall and by gender.

Results

Twenty-five adults (56% women) diagnosed with HF participated. The average age was 67 years (range: 25–88). Women attributed a wider variety of symptoms to HF than men. Some participants had difficulty differentiating whether their experiences were due to HF, side effects of their medications, or age. We found very little evidence that participants interpreted KCCQ-23 items differently based on gender.

Conclusions

Overall, our findings indicate that interpretation of the KCCQ-23 items were similar in men and women. However, some modifications to items may improve clarity of interpretation for a wide range of patients.
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Metagegevens
Titel
Investigating gender-based differential item functioning on the Kansas City Cardiomyopathy Questionnaire (KCCQ) using qualitative content analysis
Auteurs
Theresa M. Coles
Nicole Lucas
Molly McFatrich
Debra Henke
Jennifer L. Ridgeway
Emma M. Behnken
Kevin Weinfurt
Bryce B. Reeve
Amy Corneli
Shannon M. Dunlay
John A. Spertus
Li Lin
Ileana L. Piña
Fraser D. Bocell
Michelle E. Tarver
Heidi Dohse
Anindita Saha
Brittany Caldwell
Publicatiedatum
02-11-2022
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 3/2023
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-022-03276-y