01-07-2008 | Original Paper
Intestinal Permeability and Glucagon-like peptide-2 in Children with Autism: A Controlled Pilot Study
Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 6/2008
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We measured small intestinal permeability using a lactulose:mannitol sugar permeability test in a group of children with autism, with current or previous gastrointestinal complaints. Secondly, we examined whether children with autism had an abnormal glucagon-like peptide-2 (GLP-2) response to feeding. Results were compared with sibling controls and children without developmental disabilities. We enrolled 14 children with autism, 7 developmentally normal siblings of these children and 8 healthy, developmentally normal, unrelated children. Our study did not detect differences in these measures of gastrointestinal function in a group of children with autism.