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2009 | OriginalPaper | Hoofdstuk

Inleiding

Auteur : Koos van Nugteren

Gepubliceerd in: Onderzoek en behandeling van artrose en artritis

Uitgeverij: Bohn Stafleu van Loghum

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Samenvatting

Artrose is de meest voorkomende gewrichtsaandoening. Vrijwel iedereen die ouder is dan 75 jaar heeft artrose in minstens één gewricht.[1]
Voetnoten
1
Sclerose = verharding
 
2
Chondroblasten produceren vezels en grondsubstantie (samen: matrix). Chondrocyten zijn niet of nauwelijks actief in de productie hiervan.
 
3
Collageen II wordt vooral aangetroffen in bindweefsel met een hoge concentratie proteoglycanen en water: deze combinatie heeft sterk schokdempende eigenschappen.
 
4
Een dergelijk groot molecuul wordt ook wel een proteoglycaanaggregaat genoemd.
 
5
Synovia = gewrichtsvloeistof of synoviaal vocht. Synovia wordt geproduceerd in het gewrichtskapsel (= synovium).
 
6
De kraakbeencellen werden verkregen van 33 donoren bij autopsie.
 
7
Met glycosaminoglycaanketens worden bedoeld: de proteoglycanen met de daarin gebonden glucosaminoglycanen; ofwel de borsteltjes in de illustratie.
 
8
Uitgebreide informatie over dit onderwerp is te vinden in een eerder verschenen boek van Orthopedische casuïstiek: kinderorthopedie (de kwetsbaarheid van het jeugdige skelet. Koos van Nugteren, Dos Winkel).
 
9
NGH = Nederlands Huisartsen Genootschap.
 
10
CBO = Centraal Begeleidings Orgaan. Dit is een Nederlands kwaliteitsinstituut voor de gezondheidszorg.
 
11
OARSI = Osteoarthritis Research Society International.
 
12
Voor een uitgebreide beschrijving hiervan zie Orthopedische casuïstiek H 62A: addendum: ‘Birmingham Hip Resurfacing’ (BHR-)prothese of McMinn-prothese (Jan van Melkenbeek).
 
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Metagegevens
Titel
Inleiding
Auteur
Koos van Nugteren
Copyright
2009
Uitgeverij
Bohn Stafleu van Loghum
DOI
https://doi.org/10.1007/978-90-313-8000-8_1