Skip to main content
main-content
Top

Tip

Swipe om te navigeren naar een ander artikel

Gepubliceerd in: Journal of Autism and Developmental Disorders 10/2015

10-06-2015 | Brief Report

Individuals with Autistic-Like Traits Show Reduced Lateralization on a Greyscales Task

Auteurs: Michael C. W. English, Murray T. Maybery, Troy A. W. Visser

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 10/2015

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Individuals with autism spectrum conditions attend less to the left side of centrally presented face stimuli compared to neurotypical individuals, suggesting a reduction in right hemisphere activation. We examined whether a similar bias exists for non-facial stimuli in a large sample of neurotypical adults rated above- or below-average on the autism spectrum quotient (AQ). Using the “greyscales” task, we found the typical leftward bias in the below-average group was significantly reduced in the above-average group. Moreover, a negative correlation between leftward bias and the social skills factor of the AQ suggested a link between atypical hemispheric activation and social difficulties in high-AQ trait individuals that extends to non-facial stimuli.
Literatuur
go back to reference Almeida, R. A., Dickinson, J. E., Maybery, M. T., Badcock, J. C., & Badcock, D. R. (2013). Visual search targeting either local or global perceptual processes differs as a function of autistic-like traits in the typically developing population. Journal of Autism and Developmental Disorders, 43(6), 1272–1286. doi: 10.​1007/​s10803-012-1669-7. CrossRefPubMed Almeida, R. A., Dickinson, J. E., Maybery, M. T., Badcock, J. C., & Badcock, D. R. (2013). Visual search targeting either local or global perceptual processes differs as a function of autistic-like traits in the typically developing population. Journal of Autism and Developmental Disorders, 43(6), 1272–1286. doi: 10.​1007/​s10803-012-1669-7. CrossRefPubMed
go back to reference Baron-Cohen, S., Wheelwright, S., Skinner, R., Martin, J., & Clubley, E. (2001). The autism-spectrum quotient (AQ): Evidence from Asperger syndrome/high-functioning autism, males and females, scientists and mathematicians. Journal of Autism and Developmental Disorders, 31(1), 5–17. doi: 10.​1023/​A:​1005653411471. CrossRefPubMed Baron-Cohen, S., Wheelwright, S., Skinner, R., Martin, J., & Clubley, E. (2001). The autism-spectrum quotient (AQ): Evidence from Asperger syndrome/high-functioning autism, males and females, scientists and mathematicians. Journal of Autism and Developmental Disorders, 31(1), 5–17. doi: 10.​1023/​A:​1005653411471. CrossRefPubMed
go back to reference Bishop, D. V. M., Maybery, M., Maley, A., Wong, D., Hill, W., & Hallmayer, J. (2004). Using self-report to identify the broad phenotype in parents of children with autistic spectrum disorders: A study using the autism-spectrum quotient. Journal of Child Psychology and Psychiatry, 45(8), 1431–1436. doi: 10.​1111/​j.​1469-7610.​2004.​00325.​x. CrossRefPubMed Bishop, D. V. M., Maybery, M., Maley, A., Wong, D., Hill, W., & Hallmayer, J. (2004). Using self-report to identify the broad phenotype in parents of children with autistic spectrum disorders: A study using the autism-spectrum quotient. Journal of Child Psychology and Psychiatry, 45(8), 1431–1436. doi: 10.​1111/​j.​1469-7610.​2004.​00325.​x. CrossRefPubMed
go back to reference Clark, V. P., Keil, K., Maisog, J. M., Courtney, S., Ungerleider, L. G., & Haxby, J. V. (1996). Functional magnetic resonance imaging of human visual cortex during face matching: A comparison with positron emission tomography. NeuroImage, 4(1), 1–15. doi: 10.​1006/​nimg.​1996.​0025. CrossRefPubMed Clark, V. P., Keil, K., Maisog, J. M., Courtney, S., Ungerleider, L. G., & Haxby, J. V. (1996). Functional magnetic resonance imaging of human visual cortex during face matching: A comparison with positron emission tomography. NeuroImage, 4(1), 1–15. doi: 10.​1006/​nimg.​1996.​0025. CrossRefPubMed
go back to reference Davidson, R. J., & Hugdahl, K. (1996). Brain asymmetry. Cambridge: MIT Press. Davidson, R. J., & Hugdahl, K. (1996). Brain asymmetry. Cambridge: MIT Press.
go back to reference Fink, G. R., Halligan, P. W., Marshall, J. C., Frith, C. D., Frackowiak, R. S. J., & Dolan, R. J. (1996). Where in the brain does visual attention select the forest and the trees? Nature, 382(6592), 626–628. doi: 10.​1038/​382626a0. CrossRefPubMed Fink, G. R., Halligan, P. W., Marshall, J. C., Frith, C. D., Frackowiak, R. S. J., & Dolan, R. J. (1996). Where in the brain does visual attention select the forest and the trees? Nature, 382(6592), 626–628. doi: 10.​1038/​382626a0. CrossRefPubMed
go back to reference Gregory, B. L., & Plaisted-Grant, K. C. (2013). The autism-spectrum quotient and visual search: Shallow and deep autistic endophenotypes. Journal of Autism and Developmental Disorders,. doi: 10.​1007/​s10803-013-1951-3. PubMed Gregory, B. L., & Plaisted-Grant, K. C. (2013). The autism-spectrum quotient and visual search: Shallow and deep autistic endophenotypes. Journal of Autism and Developmental Disorders,. doi: 10.​1007/​s10803-013-1951-3. PubMed
go back to reference Grinter, E. J., Maybery, M. T., Van Beek, P. L., Pellicano, E., Badcock, J. C., & Badcock, D. R. (2009a). Global visual processing and self-rated autistic-like traits. Journal of Autism and Developmental Disorders, 39(9), 1278–1290. doi: 10.​1007/​s10803-009-0740-5. CrossRefPubMed Grinter, E. J., Maybery, M. T., Van Beek, P. L., Pellicano, E., Badcock, J. C., & Badcock, D. R. (2009a). Global visual processing and self-rated autistic-like traits. Journal of Autism and Developmental Disorders, 39(9), 1278–1290. doi: 10.​1007/​s10803-009-0740-5. CrossRefPubMed
go back to reference Haxby, J. V., Horwitz, B., Ungerleider, L. G., Maisog, J. M., Pietrini, P., & Grady, C. L. (1994). The functional organization of human extrastriate cortex: A PET-rCBF study of selective attention to faces and locations. The Journal of Neuroscience, 14(11 Pt 1), 6336–6353. PubMed Haxby, J. V., Horwitz, B., Ungerleider, L. G., Maisog, J. M., Pietrini, P., & Grady, C. L. (1994). The functional organization of human extrastriate cortex: A PET-rCBF study of selective attention to faces and locations. The Journal of Neuroscience, 14(11 Pt 1), 6336–6353. PubMed
go back to reference Heinze, H. J., Hinrichs, H., Scholz, M., Burchert, W., & Mangun, G. R. (1998). Neural mechanisms of global and local processing: A combined PET and ERP study. Journal of Cognitive Neuroscience, 10(4), 485–498. doi: 10.​1162/​089892998562898. CrossRefPubMed Heinze, H. J., Hinrichs, H., Scholz, M., Burchert, W., & Mangun, G. R. (1998). Neural mechanisms of global and local processing: A combined PET and ERP study. Journal of Cognitive Neuroscience, 10(4), 485–498. doi: 10.​1162/​089892998562898. CrossRefPubMed
go back to reference Hellige, J. B. (1993). Hemispheric asymmetry: What’s right and what’s left. Cambridge: Harvard University Press. Hellige, J. B. (1993). Hemispheric asymmetry: What’s right and what’s left. Cambridge: Harvard University Press.
go back to reference Hurst, R. M., Mitchell, J. T., Kimbrel, N. A., Kwapil, T. K., & Nelson-Gray, R. O. (2007). Examination of the reliability and factor structure of the autism spectrum quotient (AQ) in a non-clinical sample. Personality and Individual Differences, 43(7), 1938–1949. doi: 10.​1016/​j.​paid.​2007.​06.​012. CrossRef Hurst, R. M., Mitchell, J. T., Kimbrel, N. A., Kwapil, T. K., & Nelson-Gray, R. O. (2007). Examination of the reliability and factor structure of the autism spectrum quotient (AQ) in a non-clinical sample. Personality and Individual Differences, 43(7), 1938–1949. doi: 10.​1016/​j.​paid.​2007.​06.​012. CrossRef
go back to reference Kanwisher, N., McDermott, J., & Chun, M. M. (1997). The fusiform face area: a module in human extrastriate cortex specialized for face perception. The Journal of Neuroscience, 17(11), 4302–4311. PubMed Kanwisher, N., McDermott, J., & Chun, M. M. (1997). The fusiform face area: a module in human extrastriate cortex specialized for face perception. The Journal of Neuroscience, 17(11), 4302–4311. PubMed
go back to reference Pellicano, E., Maybery, M., Durkin, K., & Maley, A. (2006). Multiple cognitive capabilities/deficits in children with an autism spectrum disorder: “Weak” central coherence and its relationship to theory of mind and executive control. Development and Psychopathology, 18(1), 77–98. doi: 10.​1017/​S095457940606005​6. CrossRefPubMed Pellicano, E., Maybery, M., Durkin, K., & Maley, A. (2006). Multiple cognitive capabilities/deficits in children with an autism spectrum disorder: “Weak” central coherence and its relationship to theory of mind and executive control. Development and Psychopathology, 18(1), 77–98. doi: 10.​1017/​S095457940606005​6. CrossRefPubMed
go back to reference Rinehart, N. J., Bradshaw, J. L., Brereton, A. V., & Tonge, B. J. (2002). Lateralization in individuals with high-functioning autism and Asperger’s disorder: A frontostriatal model. Journal of Autism and Developmental Disorders, 32(4), 321–332. doi: 10.​1023/​A:​1016387020095. CrossRefPubMed Rinehart, N. J., Bradshaw, J. L., Brereton, A. V., & Tonge, B. J. (2002). Lateralization in individuals with high-functioning autism and Asperger’s disorder: A frontostriatal model. Journal of Autism and Developmental Disorders, 32(4), 321–332. doi: 10.​1023/​A:​1016387020095. CrossRefPubMed
go back to reference Russell-Smith, S. N., Maybery, M. T., & Bayliss, D. M. (2011). Relationships between autistic-like and schizotypy traits: An analysis using the autism spectrum quotient and oxford-liverpool inventory of feelings and experiences. Personality and Individual Differences, 51(2), 128–132. doi: 10.​1016/​j.​paid.​2011.​03.​027. CrossRef Russell-Smith, S. N., Maybery, M. T., & Bayliss, D. M. (2011). Relationships between autistic-like and schizotypy traits: An analysis using the autism spectrum quotient and oxford-liverpool inventory of feelings and experiences. Personality and Individual Differences, 51(2), 128–132. doi: 10.​1016/​j.​paid.​2011.​03.​027. CrossRef
go back to reference Russell-Smith, S. N., Maybery, M. T., Bayliss, D. M., & Sng, A. A. H. (2012). Support for a link between the local processing bias and social deficits in autism: An investigation of embedded figures test performance in non-clinical individuals. Journal of Autism and Developmental Disorders, 42(11), 2420–2430. doi: 10.​1007/​s10803-012-1506-z. CrossRefPubMed Russell-Smith, S. N., Maybery, M. T., Bayliss, D. M., & Sng, A. A. H. (2012). Support for a link between the local processing bias and social deficits in autism: An investigation of embedded figures test performance in non-clinical individuals. Journal of Autism and Developmental Disorders, 42(11), 2420–2430. doi: 10.​1007/​s10803-012-1506-z. CrossRefPubMed
go back to reference Sutherland, A., & Crewther, D. P. (2010). Magnocellular visual evoked potential delay with high autism spectrum quotient yields a neural mechanism for altered perception. Brain: A Journal of Neurology, 133(7), 2089–2097. doi: 10.​1093/​brain/​awq122. CrossRef Sutherland, A., & Crewther, D. P. (2010). Magnocellular visual evoked potential delay with high autism spectrum quotient yields a neural mechanism for altered perception. Brain: A Journal of Neurology, 133(7), 2089–2097. doi: 10.​1093/​brain/​awq122. CrossRef
go back to reference Witkin, H. A. (1971). A manual for the embedded figures tests. Palo Altom, CA: Consulting Psychologists Press. Witkin, H. A. (1971). A manual for the embedded figures tests. Palo Altom, CA: Consulting Psychologists Press.
Metagegevens
Titel
Individuals with Autistic-Like Traits Show Reduced Lateralization on a Greyscales Task
Auteurs
Michael C. W. English
Murray T. Maybery
Troy A. W. Visser
Publicatiedatum
10-06-2015
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 10/2015
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-015-2493-7