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Gepubliceerd in:

05-10-2017 | ORIGINAL PAPER

Increased Salivary IgA Response as an Indicator of Immunocompetence After a Mindfulness and Self-Compassion-Based Intervention

Auteurs: Miguel Bellosta-Batalla, Nicolás Ruiz-Robledillo, Patricia Sariñana-González, Thaïs Capella-Solano, Sara Vitoria-Estruch, Gemma Hidalgo-Moreno, Josefa Pérez-Blasco, Ángel Romero-Martínez, Luis Moya-Albiol

Gepubliceerd in: Mindfulness | Uitgave 3/2018

Abstract

Mindfulness-based interventions (MBIs) have been consolidated in healthcare settings as a highly useful therapeutic approach. Numerous studies have demonstrated their positive influence on physical and psychological well-being. In contrast, the scientific evidence concerning the potential beneficial effects of mindfulness on biological variables such as health indicators is still scarce. Therefore, in this study, we sought to analyse the influence of a mindfulness and self-compassion-based intervention on levels of salivary immunoglobulin A (sIgA) in order to validate its use in field studies. A secondary objective of the study was to confirm the associated decline in salivary cortisol (Csal) levels and improvements in self-reported health and mood already described in the general population. For this purpose, we conducted a longitudinal design, collecting saliva samples and self-reports before and immediately after the first and the last session of the intervention. Results show an improvement in health and self-reported mood, along with an increase in the sIgA levels of participants and a reduction in Csal levels. These results reinforce existing evidence of the beneficial effects of mindfulness and self-compassion on health, evaluated from a holistic perspective, considering both biological and self-reported variables. Moreover, as already done with other biological indicators such as Csal, sIgA could be used in clinical settings to evaluate the effectiveness of MBIs.

vorige artikel A Test of the Association Between Mindfulness Subcomponents and Diurnal Cortisol Patterns

volgende artikel Does Self-Compassion Facilitate Resilience to Stigma? A School-Based Study of Sexual and Gender Minority Youth

Ader, R. (2001). Psychoneuroimmunology. Current Directions in Psychological Science, 10(3), 94–98.CrossRef

Barak, Y. (2006). The immune system and happiness. Autoimmunity, 5(8), 523–527.CrossRef

Bellosta-Batalla, M., Pérez-Blasco, J., Nácher, M. J., & Moya-Albiol, L. (2016). Mejora de la empatía cognitiva y el bienestar psicológico en estudiantes de psicología tras una intervención en mindfulness. Revista Electrónica de Psicología Iztacala, 19(1), 336–354.

Bishop, S. R., Lau, M., Shapiro, S., Carlson, L., Anderson, N. D., Carmody, J., et al. (2004). Mindfulness: a proposed operational definition. Clinical Psychology: Science and Practice, 11(3), 230–241.

Black, D. S., & Slavich, G. M. (2016). Mindfulness meditation and the immune system: a systematic review of randomized controlled trials. Annals of the New York Academy of Sciences, 1373(1), 13–24.CrossRefPubMedPubMedCentral

Bosch, J. A., Ring, C., de Geus, E. J., Veerman, E. C., & Amerongen, A. V. (2002). Stress and secretory immunity. International Review of Neurobiology, 52, 213–253.CrossRefPubMed

Brod, S., Rattazzi, L., Piras, G., & D'Acquisto, F. (2014). ‘As above, so below’ examining the interplay between emotion and the immune system. Immunology, 143(3), 311–318.CrossRefPubMedPubMedCentral

Creswell, J. D., & Lindsay, E. K. (2014). How does mindfulness training affect health? A mindfulness stress buffering account. Current Directions in Psychological Science, 23(6), 401–407.CrossRef

Crowe, M., Jordan, J., Burrell, B., Jones, V., Gillon, D., & Harris, S. (2016). Mindfulness-based stress reduction for long-term physical conditions: a systematic review. Australian & New Zealand Journal of Psychiatry, 50(1), 21–32.CrossRef

Davidson, R. J., Kabat-Zinn, J., Schumacher, J., Rosenkranz, M., Muller, D., Santorelli, S. F., et al. (2003). Alterations in brain and immune function produced by mindfulness meditation. Psychosomatic Medicine, 65(4), 564–570.CrossRefPubMed

De Andrés-García, S., Moya-Albiol, L., & González-Bono, E. (2012). Salivary cortisol and immunoglobulin A: responses to stress as predictors of health complaints reported by caregivers of offspring with autistic spectrum disorder. Hormones and Behavior, 62(4), 464–474.CrossRefPubMed

Demarzo, M. M., Montero-Marin, J., Cuijpers, P., Zabaleta-del-Olmo, E., Mahtani, K. R., Vellinga, A., et al. (2015). The efficacy of mindfulness-based interventions in primary care: a meta-analytic review. Annals of Family Medicine, 13(6), 573–582.CrossRefPubMedPubMedCentral

Dhabhar, F. S. (2014). Effects of stress on immune function: the good, the bad, and the beautiful. Immunologic Research, 58(2), 193–210.CrossRefPubMed

Fuentes, I., Balaguer, I., Meliá, J. L., & García-Merita, M. (1995). Forma abreviada del Perfil de Estado de Ánimo (POMS). In E. E. Cantón (Ed.), Libro de Actas del V Congreso Nacional de Psicología de la Actividad Física y el Deporte. Valencia: Universitat de València.

Gilbert, P. (2010). Compassion-focused therapy: distinctive features. London: Routledge.

Goldberg, D., & Hillier, V. F. (1979). A scaled version of the General Health Questionnaire. Psychological Medicine, 9(1), 139–145.CrossRefPubMed

Goyal, M., Singh, S., Sibinga, E. M., Gould, N. F., Rowland-Seymour, A., Sharma, R., et al. (2014). Meditation programs for psychological stress and well-being: a systematic review and meta-analysis. JAMA Internal Medicine, 174(3), 357–368.CrossRefPubMedPubMedCentral

Hayney, M. S., Coe, C. L., Muller, D., Obasi, C. N., Backonja, U., Ewers, T., et al. (2014). Age and psychological influences on immune responses to trivalent inactivated influenza vaccine in the meditation or exercise for preventing acute respiratory infection (MEPARI) trial. Human Vaccines & Immunotherapeutics, 10(1), 83–91.CrossRef

Hofmann, S. G., Sawyer, A. T., Witt, A. A., & Oh, D. (2010). The effect of mindfulness-based therapy on anxiety and depression: a meta-analytic review. Journal of Consulting and Clinical Psychology, 78(2), 169–183.CrossRefPubMedPubMedCentral

Kabat-Zinn, J. (1990). Full catastrophe living: using the wisdom of your body and mind to face stress, pain, and illness. New York: Delacorte Press.

Kabat-Zinn, J. (2012). Mindfulness for beginners: reclaiming the present moment and your life. Boulder: Sounds True.

Kalha, I., & Sellin, J. H. (2004). Common variable immunodeficiency and the gastrointestinal tract. Current Gastroenterology Reports, 6(5), 377–383.CrossRefPubMed

Khoury, B., Lecomte, T., Fortin, G., Masse, M., Therien, P., Bouchard, V., et al. (2013). Mindfulness-based therapy: a comprehensive meta-analysis. Clinical Psychology Review, 33(6), 763–771.CrossRefPubMed

Khoury, B., Sharma, M., Rush, S. E., & Fournier, C. (2015). Mindfulness-based stress reduction for healthy individuals: a meta-analysis. Journal of Psychosomatic Research, 78(6), 519–528.CrossRefPubMed

Kiecolt-Glaser, J. K., McGuire, L., Robles, T. F., & Glaser, R. (2002). Psychoneuroimmunology: psychological influences on immune function and health. Journal of Consulting and Clinical Psychology, 70(3), 537–547.CrossRefPubMed

Lasselin, J., Alvarez-Salas, E., & Grigoleit, J. S. (2016). Well-being and immune response: a multi-system perspective. Current Opinion in Pharmacology, 29, 34–41.CrossRefPubMed

Lengacher, C. A., Kip, K. E., Post-White, J., Fitzgerald, S., Newton, C., Barta, M., et al. (2013). Lymphocyte recovery after breast cancer treatment and mindfulness-based stress reduction (MBSR) therapy. Biological Research for Nursing, 15(1), 37–47.CrossRefPubMed

Lobo, A., Pérez-Echeverría, M. J., & Artal, J. (1986). Validity of the scaled version of the General Health Questionnaire (GHQ-28) in a Spanish population. Psychological Medicine, 16(1), 135–140.CrossRefPubMed

Malarkey, W. B., Jarjoura, D., & Klatt, M. (2013). Workplace based mindfulness practice and inflammation: a randomized trial. Brain Behavior and Immunity, 27(1), 145–154.CrossRef

Matousek, R. H., Dobkin, P. L., & Pruessner, J. (2010). Cortisol as a marker for improvement in mindfulness-based stress reduction. Complementary Therapies in Clinical Practice, 16(1), 13–19.CrossRefPubMed

McEwen, B. S. (1998). Stress, adaptation, and disease. Allostasis and allostatic load. Annals of the New York Academy Science, 840, 33–44.CrossRef

McEwen, B. S., & Wingfield, J. C. (2003). The concept of allostasis in biology and biomedicine. Hormones and Behavior, 43(1), 2–15.CrossRefPubMed

McNair, D. M., Lorr, M., & Droppleman, L. F. (1971). Manual for the profile of mood states. San Diego: Educational and Industrial Testing Services.

Neff, K. D. (2003). Development and validation of a scale to measure self-compassion. Self and Identity, 2(3), 223–250.CrossRef

Neff, K. D. (2011). Self-compassion. New York: William Morrow.

Ngô, T. L. (2013). Review of the effects of mindfulness meditation on mental and physical health and its mechanisms of action. Santé Mentale au Québec, 38(2), 19–34.CrossRefPubMed

O'Leary, K., O'Neill, S., & Dockray, S. (2015). A systematic review of the effects of mindfulness interventions on cortisol. Journal of Health Psychology, 21(9), 2108–2121.CrossRefPubMed

Paszynska, E., Dmitrzak-Weglarz, M., Tyszkiewicz-Nwafor, M., & Slopien, A. (2016). Salivary alpha-amylase, secretory IgA and free cortisol as neurobiological components of the stress response in the acute phase of anorexia nervosa. The World Journal of Biological Psychiatry, 17(4), 266–273.CrossRefPubMed

Regehr, C., Glancy, D., & Pitts, A. (2013). Interventions to reduce stress in university students: a review and meta-analysis. Journal of Affective Disorders, 148(1), 1–11.CrossRefPubMed

Rein, G., Atkinson, M., & McCraty, R. (1995). The physiological and psychological effects of compassion and anger. Journal of Advancement in Medicine, 8(2), 87–105.

Romero-Martínez, A., Lila, M., Conchell, R., González-Bono, E., & Moya-Albiol, L. (2014). Immunoglobulin A response to acute stress in intimate partner violence perpetrators: the role of anger expression-out and testosterone. Biological Psychology, 96, 66–71.CrossRefPubMed

Romero-Martínez, A., Lila, M., Vitoria-Estruch, S., & Moya-Albiol, L. (2016). High immunoglobulin A levels mediate the association between high anger expression and low somatic symptoms in intimate partner violence perpetrators. Journal of Interpersonal Violence, 31(4), 732–742.CrossRefPubMed

Ruiz-Robledillo, N., Sariñana-González, P., Pérez-Blasco, J., González-Bono, E., & Moya-Albiol, L. (2015). A mindfulness-based program improves health in caregivers of people with autism spectrum disorder: a pilot study. Mindfulness, 6(4), 767–777.CrossRef

Sanada, K., Montero-Marin, J., Alda, M., Salas-Valero, M., Perez-Yus, M. C., Morillo, H., et al. (2016). Effects of mindfulness-based interventions on salivary cortisol in healthy adults: a meta-analytical review. Frontiers in Physiology, 7, 471.CrossRefPubMedPubMedCentral

Sandín, B., & Chorot, P. (1995). Escala de Síntomas Somáticos-Revisada (ESS-R). Madrid: Universidad Nacional de Educación a Distancia (UNED).

Sapolsky, R. M. (1994). Why zebras don't get ulcers. New York: Times Books.

Sapolsky, R. M., Romero, L. M., & Munck, A. U. (2000). How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. Endocrine Reviews, 21(1), 55–89.PubMed

Segal, Z. V., Williams, J. M. G., & Teasdale, J. D. (2002). Mindfulness-based cognitive therapy for depression: a new approach to preventing relapse. New York: Guilford Press.

Segerstrom, S. C., & Miller, G. E. (2004). Psychological stress and the human immune system: a meta-analytic study of 30 years of inquiry. Psychological Bulletin, 130(4), 601–630.CrossRefPubMedPubMedCentral

Seisdedos, N. (1982). STAI: Inventario de Ansiedad Estado-Rasgo. Madrid: TEA Ediciones.

Siegel, D. J. (2007). The mindful brain. Reflection and attunement in the cultivation of well-being. New York: W.W. Norton & Company.

Spielberger, C. D., Gorsuch, R., & Lushene, R. (1970). Manual for the State-Trait Anxiety Inventory. Palo Alto: Consulting Psychologist Press.

Vøllestad, J., Nielsen, M. B., & Nielsen, G. H. (2012). Mindfulness and acceptance-based interventions for anxiety disorders: a systematic review and meta-analysis. British Journal of Clinical Psychology, 51(3), 239–260.CrossRefPubMed

Watamura, S. E., Coe, C. L., Laudenslager, M. L., & Robertson, S. S. (2010). Child care setting affects salivary cortisol and antibody secretion in young children. Psychoneuroendocrinology, 35(8), 1156–1166.CrossRefPubMed

Witek-Janusek, L., Albuquerque, K., Chroniak, K. R., Chroniak, C., Durazo-Arvizu, R., & Mathews, H. L. (2008). Effect of mindfulness based stress reduction on immune function, quality of life and coping in women newly diagnosed with early stage breast cancer. Brain, Behavior, and Immunity, 22(6), 969–981.CrossRefPubMedPubMedCentral

Titel: Increased Salivary IgA Response as an Indicator of Immunocompetence After a Mindfulness and Self-Compassion-Based Intervention
Auteurs: Miguel Bellosta-Batalla
Nicolás Ruiz-Robledillo
Patricia Sariñana-González
Thaïs Capella-Solano
Sara Vitoria-Estruch
Gemma Hidalgo-Moreno
Josefa Pérez-Blasco
Ángel Romero-Martínez
Luis Moya-Albiol
Publicatiedatum: 05-10-2017
Uitgeverij: Springer US
Gepubliceerd in: Mindfulness / Uitgave 3/2018
Print ISSN: 1868-8527
Elektronisch ISSN: 1868-8535
DOI: https://doi.org/10.1007/s12671-017-0830-y

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