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Gepubliceerd in: Journal of Autism and Developmental Disorders 11/2019

21-08-2019 | Original Paper

Increased Risk of Atopic Diseases in the Siblings of Patients with Autism Spectrum Disorder: A Nationwide Population-Based Cohort Study

Auteurs: Ying-Xiu Dai, Ying-Hsuan Tai, Yun-Ting Chang, Tzeng-Ji Chen, Mu-Hong Chen

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 11/2019

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Abstract

Several studies have shown a strong association between atopic diseases and autism spectrum disorder (ASD). However, the risk of atopic diseases in individuals having ASD-affected siblings has never been investigated. This nationwide population-based cohort study included 2762 individuals with ASD-affected siblings and 11,048 controls. Diagnoses of atopic diseases, including asthma, atopic dermatitis, allergic rhinitis, and allergic conjunctivitis, were ascertained from 1996 or the birth data to the end of 2011. Individuals with ASD-affected siblings had a higher risk for asthma, atopic dermatitis, allergic rhinitis, allergic conjunctivitis, and multiple atopic diseases compared with controls. In conclusion, individuals with ASD-affected siblings were more likely than were the controls to develop atopic diseases, suggesting shared familial mechanisms underlying the two conditions.
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Metagegevens
Titel
Increased Risk of Atopic Diseases in the Siblings of Patients with Autism Spectrum Disorder: A Nationwide Population-Based Cohort Study
Auteurs
Ying-Xiu Dai
Ying-Hsuan Tai
Yun-Ting Chang
Tzeng-Ji Chen
Mu-Hong Chen
Publicatiedatum
21-08-2019
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 11/2019
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-019-04184-w