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Gepubliceerd in:

01-02-2014 | Original Paper

Incidence and Behavioral Correlates of Epileptiform Abnormalities in Autism Spectrum Disorders

Auteurs: Caitlin K. Mulligan, Doris A. Trauner

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 2/2014

Abstract

Autism spectrum disorders (ASD) are associated with an increased incidence of epilepsy and of epileptiform discharges on electroencephalograms. It is unknown whether epileptiform discharges correlate with symptoms of ASD. We completed a retrospective chart review of 101 patients with ASD who had overnight electroencephalograms. We looked for a relationship between epileptiform abnormalities and diagnosis, history of regression, communication skills, and other features associated with ASD. There was a higher incidence of epileptiform activity in children with stereotypies and aggressive behavior. The incidence of epileptiform abnormalities was significantly lower in Asperger’s compared with more severe forms of autism. Results suggest that increasing severity of autistic symptoms may be associated with higher likelihood of epileptiform abnormalities. Whether treatment alters outcome is unknown.

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Titel: Incidence and Behavioral Correlates of Epileptiform Abnormalities in Autism Spectrum Disorders
Auteurs: Caitlin K. Mulligan
Doris A. Trauner
Publicatiedatum: 01-02-2014
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 2/2014
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-013-1888-6

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