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Gepubliceerd in: Journal of Autism and Developmental Disorders 10/2014

01-10-2014 | Original Paper

In Utero Exposure to Selective Serotonin Reuptake Inhibitors and Risk for Autism Spectrum Disorder

Auteurs: Nicole B. Gidaya, Brian K. Lee, Igor Burstyn, Michael Yudell, Erik L. Mortensen, Craig J. Newschaffer

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 10/2014

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Abstract

We investigated whether there is an association between increased risk for autism spectrum disorders (ASD) and selective serotonin reuptake inhibitors (SSRIs) used during pregnancy. This study used Denmark’s health and population registers to obtain information regarding prescription drugs, ASD diagnosis, and health and socioeconomic status. There were 1.5 % of cases and 0.7 % of controls exposed to SSRIs during the pregnancy period, and higher effect estimates observed with longer use. We found evidence that in utero exposure to SSRIs increases a child’s risk associated with ASD. These results, while adding to the limited knowledge on prenatal pharmacological exposures as potential ASD risk factors, need to be balanced against the benefits of indicated medication use by pregnant mothers.
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Metagegevens
Titel
In Utero Exposure to Selective Serotonin Reuptake Inhibitors and Risk for Autism Spectrum Disorder
Auteurs
Nicole B. Gidaya
Brian K. Lee
Igor Burstyn
Michael Yudell
Erik L. Mortensen
Craig J. Newschaffer
Publicatiedatum
01-10-2014
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 10/2014
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-014-2128-4