Skip to main content
main-content
Top

Tip

Swipe om te navigeren naar een ander artikel

Gepubliceerd in: Journal of Abnormal Child Psychology 1/2008

01-01-2008

In the Face of Uncertainty: A Twin Study of Ambiguous Information, Anxiety and Depression in Children

Auteurs: Thalia C. Eley, Alice M. Gregory, Jennifer Y. F. Lau, Peter McGuffin, Maria Napolitano, Fruhling V. Rijsdijk, David M. Clark

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 1/2008

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Anxiety and depression share genetic influences, and have been associated with similar cognitive biases. Psychological theories of anxiety and depression highlight threat interpretations of ambiguity. Little is known about whether genes influence cognitive style, or its links to symptoms. We assessed ambiguous word and scenario interpretations, anxiety and depression symptoms in 300 8-year-old twin pairs. There were significant correlations between both negative interpretations of ambiguous words and scenarios and depression symptoms after controlling for anxiety symptoms (r = .13 and .31, respectively), but no significant correlations with anxiety independent of depression. Genetic effects ranged from 16% for depression to 30% for ambiguous word interpretations. Non-shared environmental influences were large (68–70%). Both genetic and environmental influences contributed to the association between depression and ambiguous scenario interpretations. These findings support psychological theories, which emphasise the role of environmental stress both on the development of threat interpretations and on their links with symptoms. The data also support a role for genetic influence on threat interpretations, which may mediate responses to stress.
Literatuur
go back to reference Alfano, C. A., Beidel, D. C., & Turner, S. M. (2002). Cognition in childhood anxiety: conceptual, methodological, and developmental issues. Clinical Psychology Review, 22, 1209–1238. PubMed Alfano, C. A., Beidel, D. C., & Turner, S. M. (2002). Cognition in childhood anxiety: conceptual, methodological, and developmental issues. Clinical Psychology Review, 22, 1209–1238. PubMed
go back to reference Alloy, L. B., Abramson, L. Y., Whitehouse, W. G., Hogan, M. E., Tashman, N. A., Steinberg, D. L. et al. (1999). Depressogenic cognitive styles: predictive validity, information processing and personality characteristics, and developmental origins. Behaviour Research and Therapy, 37, 503–531. PubMedCrossRef Alloy, L. B., Abramson, L. Y., Whitehouse, W. G., Hogan, M. E., Tashman, N. A., Steinberg, D. L. et al. (1999). Depressogenic cognitive styles: predictive validity, information processing and personality characteristics, and developmental origins. Behaviour Research and Therapy, 37, 503–531. PubMedCrossRef
go back to reference Ambrose, B., & Rholes, W. S. (1993). Automatic cognitions and the symptoms of depression and anxiety in children and adolescents: An examination of the content-specificity hypothesis. Cognitive Therapy and Research, 17, 289–308. CrossRef Ambrose, B., & Rholes, W. S. (1993). Automatic cognitions and the symptoms of depression and anxiety in children and adolescents: An examination of the content-specificity hypothesis. Cognitive Therapy and Research, 17, 289–308. CrossRef
go back to reference Barrett, P. M., Rapee, R. M., Dadds, M. M., & Ryan, S. M. (1996). Family enhancement of cognitive style in anxious and aggressive children. Journal of Abnormal Child Psychology, 24, 187–203. PubMedCrossRef Barrett, P. M., Rapee, R. M., Dadds, M. M., & Ryan, S. M. (1996). Family enhancement of cognitive style in anxious and aggressive children. Journal of Abnormal Child Psychology, 24, 187–203. PubMedCrossRef
go back to reference Beck, A. T. (1967). Depression: Causes and treatment. Philadelphia: Philadelphia University Press. Beck, A. T. (1967). Depression: Causes and treatment. Philadelphia: Philadelphia University Press.
go back to reference Beck, A. T., & Clark, D. A. (1988). Anxiety and depression: An information processing perspective. Anxiety Research, 1, 23–36. Beck, A. T., & Clark, D. A. (1988). Anxiety and depression: An information processing perspective. Anxiety Research, 1, 23–36.
go back to reference Behar, L., & Stringfield, S. (1974). A behavior rating scale for the preschool child. Developmental Psychology, 33, 3–66. Behar, L., & Stringfield, S. (1974). A behavior rating scale for the preschool child. Developmental Psychology, 33, 3–66.
go back to reference Birmaher, B., Brent, D. A., Chiappetta, L., Bridge, J., Monga, S., & Baugher, M. (1999). Psychometric properties of the Screen for Child Anxiety Related Emotional Disorders (SCARED): a replication study. Journal of the American Academy of Child and Adolescent Psychiatry, 38, 1230–1236. PubMedCrossRef Birmaher, B., Brent, D. A., Chiappetta, L., Bridge, J., Monga, S., & Baugher, M. (1999). Psychometric properties of the Screen for Child Anxiety Related Emotional Disorders (SCARED): a replication study. Journal of the American Academy of Child and Adolescent Psychiatry, 38, 1230–1236. PubMedCrossRef
go back to reference Bogels, S. M., & Zigterman, D. (2000). Dysfunctional cognitions in children with social phobia, separation anxiety disorder, and generalized anxiety disorder. Journal of Abnormal Child Psychology, 28, 205–211. PubMedCrossRef Bogels, S. M., & Zigterman, D. (2000). Dysfunctional cognitions in children with social phobia, separation anxiety disorder, and generalized anxiety disorder. Journal of Abnormal Child Psychology, 28, 205–211. PubMedCrossRef
go back to reference Butler, G., & Mathews, A. (1983). Cognitive processes in anxiety. Advances in Behaviour Research and Therapy, 5, 51–62. CrossRef Butler, G., & Mathews, A. (1983). Cognitive processes in anxiety. Advances in Behaviour Research and Therapy, 5, 51–62. CrossRef
go back to reference Chorpita, B. F., & Barlow, D. H. (1998). The development of anxiety: The role of control in the early environment. Psychological Bulletin, 124, 3–21. PubMedCrossRef Chorpita, B. F., & Barlow, D. H. (1998). The development of anxiety: The role of control in the early environment. Psychological Bulletin, 124, 3–21. PubMedCrossRef
go back to reference Cicchetti, D. (2005). Cognitive and affective neuroscience and developmental psychopathology. Development and Psychopathology, 17, 569–575. PubMed Cicchetti, D. (2005). Cognitive and affective neuroscience and developmental psychopathology. Development and Psychopathology, 17, 569–575. PubMed
go back to reference Clark, D. A., Beck, A. T., & Alford, B. A. (1999). Scientific foundations of cognitive theory and therapy of depression. New York, NY: Wiley. Clark, D. A., Beck, A. T., & Alford, B. A. (1999). Scientific foundations of cognitive theory and therapy of depression. New York, NY: Wiley.
go back to reference Clark, D. M., Salkovskis, P. M., Ost, L. G., Breitholtz, E., Koehler, K. A., Westling, B. E., et al. (1997). Misinterpretation of body sensations in panic disorder. Journal of Consulting and Clinical Psychology, 65, 203–213. PubMedCrossRef Clark, D. M., Salkovskis, P. M., Ost, L. G., Breitholtz, E., Koehler, K. A., Westling, B. E., et al. (1997). Misinterpretation of body sensations in panic disorder. Journal of Consulting and Clinical Psychology, 65, 203–213. PubMedCrossRef
go back to reference Creswell, C., Schniering, C. A., & Rapee, R. M. (2005). Threat interpretation in anxious children and their mothers: comparison with nonclinical children and the effects of treatment. Behaviour Research and Therapy, 43, 1375–1381. PubMedCrossRef Creswell, C., Schniering, C. A., & Rapee, R. M. (2005). Threat interpretation in anxious children and their mothers: comparison with nonclinical children and the effects of treatment. Behaviour Research and Therapy, 43, 1375–1381. PubMedCrossRef
go back to reference Daleiden, E. L., & Vasey, M. W. (1997). An information-processing perspective on childhood anxiety. Clinical Psychology Review, 17, 407–429. PubMedCrossRef Daleiden, E. L., & Vasey, M. W. (1997). An information-processing perspective on childhood anxiety. Clinical Psychology Review, 17, 407–429. PubMedCrossRef
go back to reference Dineen, K. A., & Hadwin, J. A. (2004). Anxious and depressive symptoms and children’s judgements of their own and others’ interpretation of ambiguous social scenarios. Journal of Anxiety Disorders, 18, 499–513. PubMedCrossRef Dineen, K. A., & Hadwin, J. A. (2004). Anxious and depressive symptoms and children’s judgements of their own and others’ interpretation of ambiguous social scenarios. Journal of Anxiety Disorders, 18, 499–513. PubMedCrossRef
go back to reference Elander, J., & Rutter, M. (1996). Use and development of the Rutter parents’ and teachers’ scales. International Journal of Methods in Psychiatric Research, 6, 63–78. CrossRef Elander, J., & Rutter, M. (1996). Use and development of the Rutter parents’ and teachers’ scales. International Journal of Methods in Psychiatric Research, 6, 63–78. CrossRef
go back to reference Eley, T. C., Bolton, D., O’Connor, T. G., Perrin, S., Smith, P., & Plomin, R. (2003). A twin study of anxiety-related behaviours in pre-school children. Journal of Child Psychology and Psychiatry, 44, 945–960. PubMedCrossRef Eley, T. C., Bolton, D., O’Connor, T. G., Perrin, S., Smith, P., & Plomin, R. (2003). A twin study of anxiety-related behaviours in pre-school children. Journal of Child Psychology and Psychiatry, 44, 945–960. PubMedCrossRef
go back to reference Eley, T. C., & Brown, T. A. (2004). Phenotypic and genetic/environmental structure of anxiety sensitivity in adolescents. Behavior Genetics, 34, 637. Eley, T. C., & Brown, T. A. (2004). Phenotypic and genetic/environmental structure of anxiety sensitivity in adolescents. Behavior Genetics, 34, 637.
go back to reference Eley, T. C., & Stevenson, J. (1999a). Exploring the covariation between anxiety and depression symptoms: A genetic analysis of the effects of age and sex. Journal of Child Psychology and Psychiatry, 40, 1273–1284. PubMedCrossRef Eley, T. C., & Stevenson, J. (1999a). Exploring the covariation between anxiety and depression symptoms: A genetic analysis of the effects of age and sex. Journal of Child Psychology and Psychiatry, 40, 1273–1284. PubMedCrossRef
go back to reference Eley, T. C., & Stevenson, J. (1999b). Using genetic analyses to clarify the distinction between depressive and anxious symptoms in children and adolescents. Journal of Abnormal Child Psychology, 27, 105–114. PubMedCrossRef Eley, T. C., & Stevenson, J. (1999b). Using genetic analyses to clarify the distinction between depressive and anxious symptoms in children and adolescents. Journal of Abnormal Child Psychology, 27, 105–114. PubMedCrossRef
go back to reference French, C., C. & Richards, A. (1992). Word association norms for a set of threat/neutral homographs. Cognition and Emotion, 6, 65–87. CrossRef French, C., C. & Richards, A. (1992). Word association norms for a set of threat/neutral homographs. Cognition and Emotion, 6, 65–87. CrossRef
go back to reference Fundudis, T., Berney, T. P., Kolvin, I., Famuyiwa, O. O., Barrett, M. L., Bhate, S. R., et al. (1991). Reliability and validity of two self-rating scales in the assessment of childhood depression. British Journal of Psychiatry, 159, 36–40. Fundudis, T., Berney, T. P., Kolvin, I., Famuyiwa, O. O., Barrett, M. L., Bhate, S. R., et al. (1991). Reliability and validity of two self-rating scales in the assessment of childhood depression. British Journal of Psychiatry, 159, 36–40.
go back to reference Goodman, R., & Scott, S. (1999). Comparing the strengths and difficulties questionnaire and the Child Behavior Checklist: Is small beautiful? Journal of Abnormal Child Psychology, 27, 17–24. PubMedCrossRef Goodman, R., & Scott, S. (1999). Comparing the strengths and difficulties questionnaire and the Child Behavior Checklist: Is small beautiful? Journal of Abnormal Child Psychology, 27, 17–24. PubMedCrossRef
go back to reference Gregory, A. M., Caspi, A., Moffitt, T. E., Koenen, K., Eley, T. C., & Poulton, R. (2007b). Juvenile mental health histories of adults with anxiety disorders. American Journal of Psychiatry, 164, 301–308. PubMedCrossRef Gregory, A. M., Caspi, A., Moffitt, T. E., Koenen, K., Eley, T. C., & Poulton, R. (2007b). Juvenile mental health histories of adults with anxiety disorders. American Journal of Psychiatry, 164, 301–308. PubMedCrossRef
go back to reference Gregory, A. M. & Eley, T. C. (2007). Genetic influences on anxiety in children: What we’ve learned and where we’re heading. Clinical Child and Family Psychology Review. DOI 10.​1007/​s10567-007-0022-8. Gregory, A. M. & Eley, T. C. (2007). Genetic influences on anxiety in children: What we’ve learned and where we’re heading. Clinical Child and Family Psychology Review. DOI 10.​1007/​s10567-007-0022-8.
go back to reference Gregory, A. M., Rijsdijk, F. V., Dahl, R. E., McGuffin, P., & Eley, T. C. (2006). Associations between sleep problems, anxiety and depression in twins aged 8 years. Pediatrics, 118, 1124–1132. PubMedCrossRef Gregory, A. M., Rijsdijk, F. V., Dahl, R. E., McGuffin, P., & Eley, T. C. (2006). Associations between sleep problems, anxiety and depression in twins aged 8 years. Pediatrics, 118, 1124–1132. PubMedCrossRef
go back to reference Gregory, A. M., Rijksdijk, F., Lau, J. Y. F., Napolitano, M., McGuffin, P., & Eley, T. C. (2007a). Interpersonal cognitions and associations with depressive symptoms in school-aged twins. Journal of Abnormal Psychology (in press). Gregory, A. M., Rijksdijk, F., Lau, J. Y. F., Napolitano, M., McGuffin, P., & Eley, T. C. (2007a). Interpersonal cognitions and associations with depressive symptoms in school-aged twins. Journal of Abnormal Psychology (in press).
go back to reference Kovacs, M. (1985). The Children’s Depression Inventory (CDI). Psychopharmacology Bulletin, 21, 995–1124. PubMed Kovacs, M. (1985). The Children’s Depression Inventory (CDI). Psychopharmacology Bulletin, 21, 995–1124. PubMed
go back to reference Lau, J. Y. F., & Eley, T. C. (2006). Changes in genetic and environmental influences on depressive symptoms across adolescence: A twin and sibling study. British Journal of Psychiatry, 189, 422–427 (in press). PubMedCrossRef Lau, J. Y. F., & Eley, T. C. (2006). Changes in genetic and environmental influences on depressive symptoms across adolescence: A twin and sibling study. British Journal of Psychiatry, 189, 422–427 (in press). PubMedCrossRef
go back to reference Lau, J. Y. F., Rijsdijk, F. V., & Eley, T. C. (2006). I think, therefore I am: A twin study of attributional style in adolescents. Journal of Child Psychology and Psychiatry, 47, 696–703. PubMedCrossRef Lau, J. Y. F., Rijsdijk, F. V., & Eley, T. C. (2006). I think, therefore I am: A twin study of attributional style in adolescents. Journal of Child Psychology and Psychiatry, 47, 696–703. PubMedCrossRef
go back to reference Little, R. J. A., & Rubin, D. B. (1987). Statistical analysis with missing data. New York: Wiley. Little, R. J. A., & Rubin, D. B. (1987). Statistical analysis with missing data. New York: Wiley.
go back to reference Martin, N., Boomsma, D. I., & Machin, G. (1997). A twin-pronged attack on complex trait. Nature Genetics, 17, 387–392. PubMedCrossRef Martin, N., Boomsma, D. I., & Machin, G. (1997). A twin-pronged attack on complex trait. Nature Genetics, 17, 387–392. PubMedCrossRef
go back to reference Mathews, A., & MacLeod, C. (2002). Induced processing biases have causal effects on anxiety. Cognition and Emotion, 16, 331–354. CrossRef Mathews, A., & MacLeod, C. (2002). Induced processing biases have causal effects on anxiety. Cognition and Emotion, 16, 331–354. CrossRef
go back to reference Monga, S., Birmaher, B., Chiappetta, L., Brent, D., Kaufman, J., Bridge, J., et al. (2000). Screen for Child Anxiety-Related Emotional Disorders (SCARED): convergent and divergent validity. Depression and Anxiety, 12, 85–91. PubMedCrossRef Monga, S., Birmaher, B., Chiappetta, L., Brent, D., Kaufman, J., Bridge, J., et al. (2000). Screen for Child Anxiety-Related Emotional Disorders (SCARED): convergent and divergent validity. Depression and Anxiety, 12, 85–91. PubMedCrossRef
go back to reference Neale, M. C., Boker, S. M., Xie, G., & Maes, H. M. (2002). Mx: Statistical Modeling (6th ed.). VCU Box 900126, Richmond, VA 23298: Department of Psychiatry. Neale, M. C., Boker, S. M., Xie, G., & Maes, H. M. (2002). Mx: Statistical Modeling (6th ed.). VCU Box 900126, Richmond, VA 23298: Department of Psychiatry.
go back to reference Neale, M. C., & Cardon, L. R. (1992). Methodology for genetic studies of twins and families. Dordrecht: Kluwer. Neale, M. C., & Cardon, L. R. (1992). Methodology for genetic studies of twins and families. Dordrecht: Kluwer.
go back to reference Nunn, J. D., Mathews, A., & Trower, P. (1997). Selective processing of concern-related information in depression. British Journal of Clinical Psychology, 36, 489–503. PubMed Nunn, J. D., Mathews, A., & Trower, P. (1997). Selective processing of concern-related information in depression. British Journal of Clinical Psychology, 36, 489–503. PubMed
go back to reference Plomin, R., Asbury, K., & Dunn, J. (2001). Why are children in the same family so different? Nonshared environment a decade later. Canadian Journal of Psychiatry, 46, 225–233. Plomin, R., Asbury, K., & Dunn, J. (2001). Why are children in the same family so different? Nonshared environment a decade later. Canadian Journal of Psychiatry, 46, 225–233.
go back to reference Price, T. S., Freeman, B., Craig, I. W., Petrill, S. A., Ebersole, L., & Plomin, R. (2000). Infant zygosity can be assigned by parental report questionnaire data. Twin Research, 3, 129–133. PubMedCrossRef Price, T. S., Freeman, B., Craig, I. W., Petrill, S. A., Ebersole, L., & Plomin, R. (2000). Infant zygosity can be assigned by parental report questionnaire data. Twin Research, 3, 129–133. PubMedCrossRef
go back to reference Rice, F., Harold, G., & Thaper, A. (2002). The genetic aetiology of childhood depression: A review. Journal of Child Psychology and Psychiatry and Allied Disciplines, 43, 65–80. CrossRef Rice, F., Harold, G., & Thaper, A. (2002). The genetic aetiology of childhood depression: A review. Journal of Child Psychology and Psychiatry and Allied Disciplines, 43, 65–80. CrossRef
go back to reference Rutter, M., Pickles, A., Murray, R., & Eaves, L. (2001). Testing hypotheses on specific environmental causal effects on behavior. Psychological Bulletin, 127, 291–324. PubMedCrossRef Rutter, M., Pickles, A., Murray, R., & Eaves, L. (2001). Testing hypotheses on specific environmental causal effects on behavior. Psychological Bulletin, 127, 291–324. PubMedCrossRef
go back to reference Stein, M. B., Jang, K. L., & Livesley, W. J. (1999). Heritability of anxiety sensitivity: A twin study. American Journal of Psychiatry, 156, 246–251. PubMed Stein, M. B., Jang, K. L., & Livesley, W. J. (1999). Heritability of anxiety sensitivity: A twin study. American Journal of Psychiatry, 156, 246–251. PubMed
go back to reference Taghavi, M. R., Moradi, A. R., Neshat-Doost, H. T., Yule, W., & Dalgleish, T. (2000). Interpretation of ambiguous emotional information in clinically anxious children and adolescents. Cognition and Emotion, 14, 809–822. CrossRef Taghavi, M. R., Moradi, A. R., Neshat-Doost, H. T., Yule, W., & Dalgleish, T. (2000). Interpretation of ambiguous emotional information in clinically anxious children and adolescents. Cognition and Emotion, 14, 809–822. CrossRef
go back to reference Thapar, A., & McGuffin, P. (1994). A twin study of depressive symptoms in childhood. British Journal of Psychiatry, 165, 259–265. PubMedCrossRef Thapar, A., & McGuffin, P. (1994). A twin study of depressive symptoms in childhood. British Journal of Psychiatry, 165, 259–265. PubMedCrossRef
go back to reference Topolski, T. D., Hewitt, J. K., Eaves, L., Meyer, J. M., Silberg, J. L., Simonoff, E., et al. (1999). Genetic and environmental influences on ratings of manifest anxiety by parents and children. Journal of Anxiety Disorders, 13, 371–397. PubMedCrossRef Topolski, T. D., Hewitt, J. K., Eaves, L., Meyer, J. M., Silberg, J. L., Simonoff, E., et al. (1999). Genetic and environmental influences on ratings of manifest anxiety by parents and children. Journal of Anxiety Disorders, 13, 371–397. PubMedCrossRef
go back to reference Trouton, A., Spinath, F. M., & Plomin, R. (2002). Twins Early Development Study (TEDS): A multivariate, longitudinal genetic investigation of language, cognition and behaviour problems in childhood. Twin Research, 5, 444–448. PubMedCrossRef Trouton, A., Spinath, F. M., & Plomin, R. (2002). Twins Early Development Study (TEDS): A multivariate, longitudinal genetic investigation of language, cognition and behaviour problems in childhood. Twin Research, 5, 444–448. PubMedCrossRef
go back to reference Williams, J. M. G., Watts, F. N., MacLeod, C., & Mathews, A. (1997). Cognitive psychology and emotional disorders (2nd ed.) Guilford: Wiley. Williams, J. M. G., Watts, F. N., MacLeod, C., & Mathews, A. (1997). Cognitive psychology and emotional disorders (2nd ed.) Guilford: Wiley.
Metagegevens
Titel
In the Face of Uncertainty: A Twin Study of Ambiguous Information, Anxiety and Depression in Children
Auteurs
Thalia C. Eley
Alice M. Gregory
Jennifer Y. F. Lau
Peter McGuffin
Maria Napolitano
Fruhling V. Rijsdijk
David M. Clark
Publicatiedatum
01-01-2008
Uitgeverij
Springer US
Gepubliceerd in
Research on Child and Adolescent Psychopathology / Uitgave 1/2008
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI
https://doi.org/10.1007/s10802-007-9159-7

Andere artikelen Uitgave 1/2008

Journal of Abnormal Child Psychology 1/2008 Naar de uitgave