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01-09-2012

Impact of diabetes mellitus on quality of life in patients with congestive heart failure

Auteurs: Buntaro Fujita, Alexander Lauten, Bjoern Goebel, Marcus Franz, Michael Fritzenwanger, Markus Ferrari, Hans R. Figulla, Friedhelm Kuethe, Christian Jung

Gepubliceerd in: Quality of Life Research | Uitgave 7/2012

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Abstract

Objectives

Congestive heart failure (CHF) and diabetes mellitus (DM) are increasing in prevalence. There are conflicting data regarding the crosstalk of DM and CHF with respect to the prognostic impact for the patients. Health-related quality of life (Hr-QoL) has been reported to be useful for risk stratification. The purpose of this study was to investigate the impact of DM on Hr-QoL in a CHF population.

Methods

325 consecutive patients with CHF were retrospectively analyzed (age 49 ± 12 years, 74.2% male, 18% had diabetes). After a median follow-up time of 7.4 years, we compared Hr-QoL of patients with and without DM. Hr-QoL was assessed using the Minnesota Living with Heart Failure Questionnaire (MLHFQ). Kaplan–Meier curves were used to compare survival.

Results

The presence of DM reduced Hr-QoL in patients with CHF, indicated by a higher overall MLHFQ score (43.5 vs. 21, P = 0.013). Kaplan–Meier survival curves showed a significant survival difference (P = 0.024). Survival rates of both groups differed significantly after 3 (P = 0.031), 5 (P = 0.006), and 10 years (P = 0.047) favoring the group without DM.

Conclusions

In patients with CHF, the coexistence of DM is associated with a reduced Hr-QoL and a particularly poor long-term survival. Our results indicate that CHF patients with DM are at increased risk.
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Metagegevens
Titel
Impact of diabetes mellitus on quality of life in patients with congestive heart failure
Auteurs
Buntaro Fujita
Alexander Lauten
Bjoern Goebel
Marcus Franz
Michael Fritzenwanger
Markus Ferrari
Hans R. Figulla
Friedhelm Kuethe
Christian Jung
Publicatiedatum
01-09-2012
Uitgeverij
Springer Netherlands
Gepubliceerd in
Quality of Life Research / Uitgave 7/2012
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-011-0039-9

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