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2021 | OriginalPaper | Hoofdstuk

16. Immuun- en targeted therapie

Auteurs : Dr. W. I. Uyterlinde, H. A. Mallo, MANP, Prof. J. B. A. G. Haanen

Gepubliceerd in: Leerboek oncologieverpleegkunde

Uitgeverij: Bohn Stafleu van Loghum

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Samenvatting

Immuuntherapie en targeted therapie zijn niet meer weg te denken bij de behandeling van maligniteiten. Door gebruik te maken van het eigen, versterkte, immuunsysteem van de patiënt en het doelgericht blokkeren van targets is er sprake van een toegenomen overleving bij een aantal soorten tumoren. Voortschrijdend inzicht door wetenschappelijk onderzoek leidt tot steeds meer behandelindicaties. De behandelingen kunnen echter ook ernstige bijwerkingen veroorzaken. Immuuntherapie kan auto-immuungelijkende reacties oproepen die levensbedreigend kunnen zijn. Doelgerichte therapie vergt kennis van de target waartegen het medicijn is gericht. Blokkade hiervan veroorzaakt voor iedere target een ander bijwerkingenprofiel. Naast deze behandelingen lijken vaccinatie- en celtherapie veelbelovend, maar deze vinden veelal nog plaats in onderzoeksverband. Gedegen kennis van de (bijwerkingen) van immuun- en targeted therapie is nodig om de patiënt voor te kunnen lichten. Het is belangrijk om als zorgverlener symptomen in te kunnen schatten zodat de patiënt zo min mogelijk schade ondervindt van de behandeling.
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Metagegevens
Titel
Immuun- en targeted therapie
Auteurs
Dr. W. I. Uyterlinde
H. A. Mallo, MANP
Prof. J. B. A. G. Haanen
Copyright
2021
Uitgeverij
Bohn Stafleu van Loghum
DOI
https://doi.org/10.1007/978-90-368-2645-7_16