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2013 | OriginalPaper | Hoofdstuk

10. Immuno- en targeted therapie

Auteurs : H.A. Mallo, J.B.A.G. Haanen

Gepubliceerd in: Oncologie

Uitgeverij: Bohn Stafleu van Loghum

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Inleiding

Kankercellen ontstaan doordat veranderingen optreden tijdens complexe biologische processen in de cel. Deze veranderingen zijn het gevolg van beschadigingen in het erfelijkheidsmateriaal (DNA) in de cel. Deze beschadigingen, die veelal gedurende een langere periode cumuleren, leiden tot een veranderd gedrag van de cel, bijvoorbeeld onafhankelijkheid van groeifactoren voor deling. Kankercellen kunnen door het immuunsysteem worden opgeruimd, maar ze zijn ook in staat overlevingsstrategieën te ontwikkelen en kunnen op die manier ontsnappen aan het immuunsysteem en groeien of zich vermenigvuldigen.
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Metagegevens
Titel
Immuno- en targeted therapie
Auteurs
H.A. Mallo
J.B.A.G. Haanen
Copyright
2013
Uitgeverij
Bohn Stafleu van Loghum
DOI
https://doi.org/10.1007/978-90-313-8871-4_10