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01-11-2009 | Interuniversity Cardiology Institute of the Netherlands | Uitgave 11/2009

Netherlands Heart Journal 11/2009

Imaging atherosclerotic plaque composition with intracoronary optical coherence tomography

Tijdschrift:
Netherlands Heart Journal > Uitgave 11/2009
Auteurs:
G. van Soest, T. P. M. Goderie, N. Gonzalo, S. Koljenović, G. L. J. H. van Leenders, E. Regar, P. W. Serruys, A. F. W. van der Steen
Belangrijke opmerkingen
Department of Biomedical Engineering, Thorax Center, Erasmus MC, Rotterdam, the Netherlands
Department of Interventional Cardiology, Thorax Center, Erasmus MC, Rotterdam, the Netherlands
Department of Pathology, Erasmus MC, Rotterdam, The Netherlands
Department of Biomedical Engineering, Thorax Center, Erasmus MC, Rotterdam, and Interuniversity Cardiology Institute of the Netherlands, the Netherlands
G. van Soest Department of Biomedical Engineering, Thorax Center, Erasmus MC, PO Box 2040, 3000CA Rotterdam, the Netherlands

Abstract

Optical coherence tomography (OCT) allows highly accurate diagnosis of atherosclerotic plaques, including measurement of the thickness of fibrous caps, permitting an assessment of the risk of rupture. While the OCT image presents morphological information in highly resolved detail, it relies on interpretation by trained readers for the identification of tissue type. We developed a method for quantitative classification of atherosclerotic plaque constituents. The optical attenuation coefficient μt distinguishes different tissue types: necrotic core and macrophage infiltration exhibit strong attenuation, μt≥10 mm−1, while calcific and fibrous tissue have a lower μt≈2–5 mm−1. (Neth Heart J 2009;17:448–50.)

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Netherlands Heart Journal

Het Netherlands Heart Journal wordt uitgegeven in samenwerking met de Nederlandse Vereniging voor Cardiologie en de Nederlandse Hartstichting. Het tijdschrift is Engelstalig en wordt gratis beschikbaa ...

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