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01-08-2012 | ICIN | Uitgave 7-8/2012 Open Access

Netherlands Heart Journal 7-8/2012

Idiopathic dilated cardiomyopathy: possible triggers and treatment strategies

Tijdschrift:
Netherlands Heart Journal > Uitgave 7-8/2012
Auteurs:
M. Hazebroek, R. Dennert, S. Heymans

Abstract

Despite recent advances in the management of patients with heart failure, morbidity and mortality rates remain high. Common causes of heart failure are ischaemic heart disease, uncontrolled hypertension and valvular disease. However, in up to 50 % of the cases its exact cause remains initially unknown; this condition is called idiopathic dilated cardiomyopathy (DCM). Improved diagnostic methods, most notably the advancements in molecular and immunohistological biopsy techniques and genetic research, have endorsed a new era in the diagnosis and classification of patients with idiopathic DCM. These insights have led to novel aetiology-based treatment strategies and improved outcome. The present article will briefly discuss all causes of DCM with a special focus on inflammatory- and virus-mediated forms of DCM.

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Netherlands Heart Journal

Het Netherlands Heart Journal wordt uitgegeven in samenwerking met de Nederlandse Vereniging voor Cardiologie en de Nederlandse Hartstichting. Het tijdschrift is Engelstalig en wordt gratis beschikbaa ...

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