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Journal of Autism and Developmental Disorders

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28-01-2021 | Original Paper

Identifying Subgroups of Toddlers with DSM-5 Autism Spectrum Disorder Based on Core Symptoms

Auteurs: Holly K. Harris, Collin Lee, Georgios D. Sideridis, William J. Barbaresi, Elizabeth Harstad

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 12/2021

Abstract

The objective of this study was to identify subgroups of toddlers with DSM-5 ASD based on core ASD symptoms using a person-based analytical framework. This is a retrospective study of 500 toddlers (mean age 26 months, 79% male) with DSM-5 ASD. Data were analyzed using latent class analyses in which profiles were formed based on ASD symptomatology. Social communication (SC) symptoms favored a three-class solution, while restricted/repetitive behaviors (RRBs) favored a two-class solution. Classes with higher consistency of SC deficits were younger, with lower developmental functioning. The class with more RRBs was older, with higher functioning. If confirmed in other populations, these classes may more precisely characterize subgroups within the heterogeneous group of toddlers at time of ASD diagnosis.

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Titel: Identifying Subgroups of Toddlers with DSM-5 Autism Spectrum Disorder Based on Core Symptoms
Auteurs: Holly K. Harris
Collin Lee
Georgios D. Sideridis
William J. Barbaresi
Elizabeth Harstad
Publicatiedatum: 28-01-2021
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 12/2021
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-021-04879-z

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