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Research on Child and Adolescent Psychopathology

Gepubliceerd in:

18-02-2017

HPA-Axis Activation as a Key Moderator of Childhood Trauma Exposure and Adolescent Mental Health

Auteurs: Kate R. Kuhlman, Elisa G. Geiss, Ivan Vargas, Nestor Lopez-Duran

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 1/2018

Abstract

Individual differences in a child’s sensitivity to stress may influence whether youth exposed to trauma develop symptoms of psychopathology. We examined the interaction between HPA-axis reactivity to an acute stressor and exposure to different types of childhood trauma as predictors of mental health symptoms in a sample of youth. Youth (n = 121, ages 9–16; 47% female) completed a standardized stress task, including 5 post-stress salivary cortisol samples. Parents also completed the Child Behavior Checklist as a measure of child internalizing and externalizing symptoms in the past month, and completed the Early Trauma Inventory (ETI) as a measure of their child’s trauma exposure. More emotional abuse and non-intentional trauma were associated with greater internalizing symptoms. Youth exposed to physical abuse who demonstrated slower HPA-axis reactivity had elevated internalizing and externalizing symptoms. Youth exposed to emotional abuse or non-intentional traumatic events who demonstrated faster HPA-axis reactivity had elevated internalizing and externalizing symptoms. Profiles of exaggerated or attenuated HPA-axis reactivity to acute stress may be risk factors for psychopathology in children facing different stressful social environments.

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Previous investigations using this sample found exposure to any trauma during infancy was related to patterns of within-subject change in HPA-axis reactivity, however the pattern of results in the adjusted models remain unchanged when accounting for exposure to any trauma during infancy (Kuhlman et al. 2015b).

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Titel: HPA-Axis Activation as a Key Moderator of Childhood Trauma Exposure and Adolescent Mental Health
Auteurs: Kate R. Kuhlman
Elisa G. Geiss
Ivan Vargas
Nestor Lopez-Duran
Publicatiedatum: 18-02-2017
Uitgeverij: Springer US
Gepubliceerd in: Research on Child and Adolescent Psychopathology / Uitgave 1/2018
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI: https://doi.org/10.1007/s10802-017-0282-9

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