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18-06-2024

How do patients interpret and respond to a novel patient-reported eastern cooperative oncology group performance status (ECOG)?

Auteurs: Rebecca Fillipo, Thomas W. Leblanc, Katelyn E. Plyler, Cara Arizmendi, Debra M. Henke, Theresa Coles

Gepubliceerd in: Quality of Life Research | Uitgave 9/2024

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Abstract

Purpose

Performance status is an important concept in oncology, but is typically clinician-reported. Efforts are underway to include patient-reported measures in cancer care, which may improve patient symptoms, quality of life and overall survival. The purpose of this study was to gain a preliminary understanding of how patients determined their physical performance status based on a novel patient-reported version of the Eastern Cooperative Oncology Group Performance Status (ECOG) scale.

Methods

We conducted qualitative interviews, including concept elicitation and cognitive interviewing as part of the Patient Reports of Physical Functioning Study (PROPS) to investigate how participants selected their answers to a novel patient-reported ECOG. Participants were administered the patient-reported ECOG and asked to describe devices and modifications used to keep up with daily activities.

Results

Participants generally understood the ECOG as intended. Participants with recent changes in status had some difficulty selecting an answer. Most participants used modifications and assistive devices in their daily lives but did not incorporate these into their rational for the ECOG.

Conclusion

The potential benefits of a patient-reported ECOG are numerous and this study demonstrates that participants were able to understand and answer the patient-reported ECOG as intended. We recommend future evaluation for the most-appropriate recall period, whether to include modifications in the ECOG instructions, and if increasing the number of response options to the patient-reported ECOG may improve confidence when providing an answer.
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Literatuur
1.
go back to reference Broderick, J. E., May, M., Schwartz, J. E., Li, M., Mejia, A., Nocera, L., Kolatkar, A., Ueno, N. T., Yennu, S., Lee, J. S. H., Hanlon, S. E., Philips, C., Shahabi, F. A., Kuhn, C., P., & Nieva, J. (2019). Patient reported outcomes can improve performance status assessment: A pilot study. J Patient Rep Outcomes, 3(1), 41.CrossRefPubMedPubMedCentral Broderick, J. E., May, M., Schwartz, J. E., Li, M., Mejia, A., Nocera, L., Kolatkar, A., Ueno, N. T., Yennu, S., Lee, J. S. H., Hanlon, S. E., Philips, C., Shahabi, F. A., Kuhn, C., P., & Nieva, J. (2019). Patient reported outcomes can improve performance status assessment: A pilot study. J Patient Rep Outcomes, 3(1), 41.CrossRefPubMedPubMedCentral
2.
go back to reference Sorensen, J. B., Klee, M., Palshof, T., & Hansen, H. H. (1993). Performance status assessment in cancer patients. An inter-observer variability study. British Journal of Cancer, 67(4), 773–775.CrossRefPubMedPubMedCentral Sorensen, J. B., Klee, M., Palshof, T., & Hansen, H. H. (1993). Performance status assessment in cancer patients. An inter-observer variability study. British Journal of Cancer, 67(4), 773–775.CrossRefPubMedPubMedCentral
3.
go back to reference Oken, M. M., Creech, R. H., Tormey, D. C., Horton, J., Davis, T. E., McFadden, E. T., & Carbone, P. P. (1982). Toxicity and response criteria of the Eastern Cooperative Oncology Group. American Journal of Clinical Oncology, 5(6), 649–655.CrossRefPubMed Oken, M. M., Creech, R. H., Tormey, D. C., Horton, J., Davis, T. E., McFadden, E. T., & Carbone, P. P. (1982). Toxicity and response criteria of the Eastern Cooperative Oncology Group. American Journal of Clinical Oncology, 5(6), 649–655.CrossRefPubMed
4.
go back to reference Al-Rashdan, A., Sutradhar, R., Nazeri-Rad, N., Yao, C., & Barbera, L. (2021). Comparing the ability of physician-reported Versus patient-reported performance status to Predict Survival in a Population-based cohort of newly diagnosed Cancer patients. Clinical Oncology (Royal College of Radiologists), 33(7), 476–482.CrossRef Al-Rashdan, A., Sutradhar, R., Nazeri-Rad, N., Yao, C., & Barbera, L. (2021). Comparing the ability of physician-reported Versus patient-reported performance status to Predict Survival in a Population-based cohort of newly diagnosed Cancer patients. Clinical Oncology (Royal College of Radiologists), 33(7), 476–482.CrossRef
5.
go back to reference Aier, I., Semwal, R., Sharma, A., & Varadwaj, P. K. (2019). A systematic assessment of statistics, risk factors, and underlying features involved in pancreatic cancer. Cancer Epidemiology, 58, 104–110.CrossRefPubMed Aier, I., Semwal, R., Sharma, A., & Varadwaj, P. K. (2019). A systematic assessment of statistics, risk factors, and underlying features involved in pancreatic cancer. Cancer Epidemiology, 58, 104–110.CrossRefPubMed
6.
go back to reference Bachelot, T., Ray-Coquard, I., Catimel, G., Ardiet, C., Guastalla, J. P., Dumortier, A., Chauvin, F., Droz, J. P., Philip, T., & Clavel, M. (2000). Multivariable analysis of prognostic factors for toxicity and survival for patients enrolled in phase I clinical trials. Annals of Oncology, 11(2), 151–156.CrossRefPubMed Bachelot, T., Ray-Coquard, I., Catimel, G., Ardiet, C., Guastalla, J. P., Dumortier, A., Chauvin, F., Droz, J. P., Philip, T., & Clavel, M. (2000). Multivariable analysis of prognostic factors for toxicity and survival for patients enrolled in phase I clinical trials. Annals of Oncology, 11(2), 151–156.CrossRefPubMed
7.
go back to reference Jensen, R. E., Potosky, A. L., Reeve, B. B., Hahn, E., Cella, D., Fries, J., Smith, A. W., Keegan, T. H., Wu, X. C., Paddock, L., & Moinpour, C. M. (2015). Validation of the PROMIS physical function measures in a diverse US population-based cohort of cancer patients. Quality of Life Research, 24(10), 2333–2344.CrossRefPubMedPubMedCentral Jensen, R. E., Potosky, A. L., Reeve, B. B., Hahn, E., Cella, D., Fries, J., Smith, A. W., Keegan, T. H., Wu, X. C., Paddock, L., & Moinpour, C. M. (2015). Validation of the PROMIS physical function measures in a diverse US population-based cohort of cancer patients. Quality of Life Research, 24(10), 2333–2344.CrossRefPubMedPubMedCentral
8.
go back to reference Zimmermann, C., Burman, D., Bandukwala, S., Seccareccia, D., Kaya, E., Bryson, J., Rodin, G., & Lo, C. (2010). Nurse and physician inter-rater agreement of three performance status measures in palliative care outpatients. Supportive Care in Cancer, 18(5), 609–616.CrossRefPubMed Zimmermann, C., Burman, D., Bandukwala, S., Seccareccia, D., Kaya, E., Bryson, J., Rodin, G., & Lo, C. (2010). Nurse and physician inter-rater agreement of three performance status measures in palliative care outpatients. Supportive Care in Cancer, 18(5), 609–616.CrossRefPubMed
9.
go back to reference Kos, M., Pijnappel, E. N., Buffart, L. M., Balvers, B. R., Kampshoff, C. S., Wilmink, J. W., van Laarhoven, H. W. M., & van Oijen, M. G. H. (2021). The association between wearable activity monitor metrics and performance status in oncology: A systematic review. Supportive Care in Cancer, 29(11), 7085–7099.CrossRefPubMedPubMedCentral Kos, M., Pijnappel, E. N., Buffart, L. M., Balvers, B. R., Kampshoff, C. S., Wilmink, J. W., van Laarhoven, H. W. M., & van Oijen, M. G. H. (2021). The association between wearable activity monitor metrics and performance status in oncology: A systematic review. Supportive Care in Cancer, 29(11), 7085–7099.CrossRefPubMedPubMedCentral
10.
go back to reference Bergerot, C. D., Philip, E. J., Bergerot, P. G., Hsu, J., Dizman, N., Salgia, M., Salgia, N., Vaishampayan, U., Battle, D., Loscalzo, M., Dale, W., & Pal, S. K. (2021). Discrepancies between genitourinary cancer patients’ and clinicians’ characterization of the Eastern Cooperative Oncology Group performance status. Cancer, 127(3), 354–358.CrossRefPubMed Bergerot, C. D., Philip, E. J., Bergerot, P. G., Hsu, J., Dizman, N., Salgia, M., Salgia, N., Vaishampayan, U., Battle, D., Loscalzo, M., Dale, W., & Pal, S. K. (2021). Discrepancies between genitourinary cancer patients’ and clinicians’ characterization of the Eastern Cooperative Oncology Group performance status. Cancer, 127(3), 354–358.CrossRefPubMed
11.
go back to reference Liu, M. A., Hshieh, T., Condron, N., Wadleigh, M., Abel, G. A., & Driver, J. A. (2016). Relationship between physician and patient assessment of performance status and survival in a large cohort of patients with haematologic malignancies. British Journal of Cancer, 115(7), 858–861.CrossRefPubMedPubMedCentral Liu, M. A., Hshieh, T., Condron, N., Wadleigh, M., Abel, G. A., & Driver, J. A. (2016). Relationship between physician and patient assessment of performance status and survival in a large cohort of patients with haematologic malignancies. British Journal of Cancer, 115(7), 858–861.CrossRefPubMedPubMedCentral
12.
go back to reference Datta, S. S., Ghosal, N., Daruvala, R., Chakraborty, S., Shrimali, R. K., van Zanten, C., Parry, J., Agrawal, S., Atreya, S., Sinha, S., Chatterjee, S., & Gollins, S. (2019). How do clinicians rate patient’s performance status using the ECOG performance scale? A mixed-methods exploration of variability in decision-making in oncology. Ecancermedicalscience, 13, 913.CrossRefPubMedPubMedCentral Datta, S. S., Ghosal, N., Daruvala, R., Chakraborty, S., Shrimali, R. K., van Zanten, C., Parry, J., Agrawal, S., Atreya, S., Sinha, S., Chatterjee, S., & Gollins, S. (2019). How do clinicians rate patient’s performance status using the ECOG performance scale? A mixed-methods exploration of variability in decision-making in oncology. Ecancermedicalscience, 13, 913.CrossRefPubMedPubMedCentral
13.
go back to reference Takvorian, S. U., Anderson, R. T., Gabriel, P. E., Poznyak, D., Lee, S., Simon, S., Barrett, K., & Shulman, L. N. (2022). Real-world adherence to patient-reported outcome monitoring as a Cancer Care Quality Metric. JCO Oncol Pract, 18(9), e1454–e1465.CrossRefPubMed Takvorian, S. U., Anderson, R. T., Gabriel, P. E., Poznyak, D., Lee, S., Simon, S., Barrett, K., & Shulman, L. N. (2022). Real-world adherence to patient-reported outcome monitoring as a Cancer Care Quality Metric. JCO Oncol Pract, 18(9), e1454–e1465.CrossRefPubMed
14.
go back to reference Kotronoulas, G., Kearney, N., Maguire, R., Harrow, A., Di Domenico, D., Croy, S., & MacGillivray, S. (2014). What is the value of the routine use of patient-reported outcome measures toward improvement of patient outcomes, processes of care, and health service outcomes in cancer care? A systematic review of controlled trials. Journal of Clinical Oncology, 32(14), 1480–1501.CrossRefPubMed Kotronoulas, G., Kearney, N., Maguire, R., Harrow, A., Di Domenico, D., Croy, S., & MacGillivray, S. (2014). What is the value of the routine use of patient-reported outcome measures toward improvement of patient outcomes, processes of care, and health service outcomes in cancer care? A systematic review of controlled trials. Journal of Clinical Oncology, 32(14), 1480–1501.CrossRefPubMed
15.
go back to reference Basch, E., Deal, A. M., Kris, M. G., Scher, H. I., Hudis, C. A., Sabbatini, P., Rogak, L., Bennett, A. V., Dueck, A. C., Atkinson, T. M., Chou, J. F., Dulko, D., Sit, L., Barz, A., Novotny, P., Fruscione, M., Sloan, J. A., & Schrag, D. (2016). Symptom Monitoring with patient-reported outcomes during Routine Cancer treatment: A Randomized Controlled Trial. Journal of Clinical Oncology, 34(6), 557–565.CrossRefPubMed Basch, E., Deal, A. M., Kris, M. G., Scher, H. I., Hudis, C. A., Sabbatini, P., Rogak, L., Bennett, A. V., Dueck, A. C., Atkinson, T. M., Chou, J. F., Dulko, D., Sit, L., Barz, A., Novotny, P., Fruscione, M., Sloan, J. A., & Schrag, D. (2016). Symptom Monitoring with patient-reported outcomes during Routine Cancer treatment: A Randomized Controlled Trial. Journal of Clinical Oncology, 34(6), 557–565.CrossRefPubMed
16.
go back to reference Gotay, C. C., Kawamoto, C. T., Bottomley, A., & Efficace, F. (2008). The prognostic significance of patient-reported outcomes in cancer clinical trials. Journal of Clinical Oncology, 26(8), 1355–1363.CrossRefPubMed Gotay, C. C., Kawamoto, C. T., Bottomley, A., & Efficace, F. (2008). The prognostic significance of patient-reported outcomes in cancer clinical trials. Journal of Clinical Oncology, 26(8), 1355–1363.CrossRefPubMed
17.
go back to reference Basch, E., Deal, A. M., Dueck, A. C., Scher, H. I., Kris, M. G., Hudis, C., & Schrag, D. (2017). Overall survival results of a trial assessing patient-reported outcomes for Symptom Monitoring during Routine Cancer Treatment. Journal of the American Medical Association, 318(2), 197–198.CrossRefPubMed Basch, E., Deal, A. M., Dueck, A. C., Scher, H. I., Kris, M. G., Hudis, C., & Schrag, D. (2017). Overall survival results of a trial assessing patient-reported outcomes for Symptom Monitoring during Routine Cancer Treatment. Journal of the American Medical Association, 318(2), 197–198.CrossRefPubMed
18.
go back to reference Loprinzi, C. L., Laurie, J. A., Wieand, H. S., Krook, J. E., Novotny, P. J., Kugler, J. W., Bartel, J., Law, M., Bateman, M., Klatt, N. E., et al. (1994). Prospective evaluation of prognostic variables from patient-completed questionnaires. North Central Cancer Treatment Group. Journal of Clinical Oncology, 12(3), 601–607.CrossRefPubMed Loprinzi, C. L., Laurie, J. A., Wieand, H. S., Krook, J. E., Novotny, P. J., Kugler, J. W., Bartel, J., Law, M., Bateman, M., Klatt, N. E., et al. (1994). Prospective evaluation of prognostic variables from patient-completed questionnaires. North Central Cancer Treatment Group. Journal of Clinical Oncology, 12(3), 601–607.CrossRefPubMed
19.
go back to reference Popovic, G., Harhara, T., Pope, A., Al-Awamer, A., Banerjee, S., Bryson, J., Mak, E., Lau, J., Hannon, B., Swami, N., Le, L. W., & Zimmermann, C. (2018). Patient-reported functional status in outpatients with Advanced Cancer: Correlation with physician-reported scores and Survival. J Pain Symptom Manage, 55(6), 1500–1508.CrossRefPubMed Popovic, G., Harhara, T., Pope, A., Al-Awamer, A., Banerjee, S., Bryson, J., Mak, E., Lau, J., Hannon, B., Swami, N., Le, L. W., & Zimmermann, C. (2018). Patient-reported functional status in outpatients with Advanced Cancer: Correlation with physician-reported scores and Survival. J Pain Symptom Manage, 55(6), 1500–1508.CrossRefPubMed
20.
go back to reference Wood, W. A., Deal, A. M., Stover, A. M., & Basch, E. (2021). Comparing clinician-assessed and patient-reported performance status for Predicting Morbidity and Mortality in patients with Advanced Cancer receiving chemotherapy. JCO Oncol Pract, 17(2), e111–e118.CrossRefPubMedPubMedCentral Wood, W. A., Deal, A. M., Stover, A. M., & Basch, E. (2021). Comparing clinician-assessed and patient-reported performance status for Predicting Morbidity and Mortality in patients with Advanced Cancer receiving chemotherapy. JCO Oncol Pract, 17(2), e111–e118.CrossRefPubMedPubMedCentral
21.
go back to reference Willis, G. B. (2015). Analysis of the cognitive interview in Questionnaire Design. Oxford University Press, Incorporated. Willis, G. B. (2015). Analysis of the cognitive interview in Questionnaire Design. Oxford University Press, Incorporated.
22.
go back to reference Coles, T., Plyler, K., Hernandez, A., Fillipo, R., Henke, D. M., Arizmendi, C., Lagoo-Deenadayalan, S., Goodwin, C. R., LeBlanc, T. W., Horodniceanu, E. G., Bhatnagar, V., Reeve, B. B., & Weinfurt, K. P. (2024). What facets of physical function are most important to adults diagnosed with cancer? Qual Life Res. Coles, T., Plyler, K., Hernandez, A., Fillipo, R., Henke, D. M., Arizmendi, C., Lagoo-Deenadayalan, S., Goodwin, C. R., LeBlanc, T. W., Horodniceanu, E. G., Bhatnagar, V., Reeve, B. B., & Weinfurt, K. P. (2024). What facets of physical function are most important to adults diagnosed with cancer? Qual Life Res.
23.
go back to reference Coles, T., Fillipo, R., Plyler, K., Hernandez, A., Henke, D. M., Arizmendi, C., Cantrell, S., Lagoo-Deenadayalan, S., Goodwin, R., LeBlanc, C., Horodniceanu, T. W., Bhatnagar, E. G., Reeve, V., B. B., & Weinfurt, K. (2024). Facets of physical function assessed by patient-reported outcome measures in oncology research. Qual Life Res. Coles, T., Fillipo, R., Plyler, K., Hernandez, A., Henke, D. M., Arizmendi, C., Cantrell, S., Lagoo-Deenadayalan, S., Goodwin, R., LeBlanc, C., Horodniceanu, T. W., Bhatnagar, E. G., Reeve, V., B. B., & Weinfurt, K. (2024). Facets of physical function assessed by patient-reported outcome measures in oncology research. Qual Life Res.
24.
go back to reference Sandelowski, M. (2000). Whatever happened to qualitative description? Research in Nursing & Health, 23(4), 334–340.CrossRef Sandelowski, M. (2000). Whatever happened to qualitative description? Research in Nursing & Health, 23(4), 334–340.CrossRef
25.
go back to reference Patton, M. Q. (2015). Qualitative research & evaluation methods: integrating theory and practice ((Fourth edition. ed.). ed.): SAGE Publications, Inc. Patton, M. Q. (2015). Qualitative research & evaluation methods: integrating theory and practice ((Fourth edition. ed.). ed.): SAGE Publications, Inc.
26.
go back to reference Guest, G., Bunce, A., & Johnson, L. (2006). How many interviews are Enough?An experiment with data saturation and variability. Field Methods, 18(1), 59–82.CrossRef Guest, G., Bunce, A., & Johnson, L. (2006). How many interviews are Enough?An experiment with data saturation and variability. Field Methods, 18(1), 59–82.CrossRef
27.
go back to reference Tourangeau, R. (1984). Cognitive Sciences and survey methods. Cognitive aspects of survey methodology: building a bridge between disciplines. Tourangeau, R. (1984). Cognitive Sciences and survey methods. Cognitive aspects of survey methodology: building a bridge between disciplines.
28.
go back to reference Collins, D. (2015). Cognitive interviewing practice. SAGE Publications Ltd. Collins, D. (2015). Cognitive interviewing practice. SAGE Publications Ltd.
29.
go back to reference Lay, K., Crocker, M., Engel, L., Ratcliffe, J., Charlton, S., & Hutchinson, C. (2023). How do older adults receiving aged care services understand and respond to the EQ-5D-5L? A think-aloud study in residential care. Quality of Life Research, 32(11), 3161–3170.CrossRefPubMedPubMedCentral Lay, K., Crocker, M., Engel, L., Ratcliffe, J., Charlton, S., & Hutchinson, C. (2023). How do older adults receiving aged care services understand and respond to the EQ-5D-5L? A think-aloud study in residential care. Quality of Life Research, 32(11), 3161–3170.CrossRefPubMedPubMedCentral
30.
go back to reference Ho, S., Culligan, M., Friedberg, J., Goloubeva, O., & Marchese, V. (2022). Examining the impact of physical function performance in predicting patient outcomes after lung-sparing surgery for malignant pleural mesothelioma. Disability and Rehabilitation, 44(22), 6676–6683.CrossRefPubMed Ho, S., Culligan, M., Friedberg, J., Goloubeva, O., & Marchese, V. (2022). Examining the impact of physical function performance in predicting patient outcomes after lung-sparing surgery for malignant pleural mesothelioma. Disability and Rehabilitation, 44(22), 6676–6683.CrossRefPubMed
31.
go back to reference Kim, Y., Krishnan, C. K., Kim, H. S., Cho, H. S., & Han, I. (2020). Ambulation recovery after surgery for metastases to the Femur. The Oncologist, 25(1), e178–e185.CrossRefPubMed Kim, Y., Krishnan, C. K., Kim, H. S., Cho, H. S., & Han, I. (2020). Ambulation recovery after surgery for metastases to the Femur. The Oncologist, 25(1), e178–e185.CrossRefPubMed
32.
go back to reference Coles, T., Plyler, K., Hernandez, A., Fillipo, R., Henke, D., Arizmendi, C., Cantrell, S., Lagoo-Deenadayalan, S., Goodwin, R., LeBlanc, T. W., Horodniceanu, E. G., Bhatnagar, V., Reeve, B. B., & Weinfurt, K. (2024). Recalling what we thought we knew about recall periods: A qualitative descriptive study of how adults diagnosed with Cancer interpret physical function patient-reported outcome items with and without Recall Periods. Under Development. Coles, T., Plyler, K., Hernandez, A., Fillipo, R., Henke, D., Arizmendi, C., Cantrell, S., Lagoo-Deenadayalan, S., Goodwin, R., LeBlanc, T. W., Horodniceanu, E. G., Bhatnagar, V., Reeve, B. B., & Weinfurt, K. (2024). Recalling what we thought we knew about recall periods: A qualitative descriptive study of how adults diagnosed with Cancer interpret physical function patient-reported outcome items with and without Recall Periods. Under Development.
33.
go back to reference Jeon, H. J., Shim, E. J., Shin, Y. W., Oh, D. Y., Im, S. A., Heo, D. S., & Hahm, B. J. (2007). Discrepancies in performance status scores as determined by cancer patients and oncologists: Are they influenced by depression? General Hospital Psychiatry, 29(6), 555–561.CrossRefPubMed Jeon, H. J., Shim, E. J., Shin, Y. W., Oh, D. Y., Im, S. A., Heo, D. S., & Hahm, B. J. (2007). Discrepancies in performance status scores as determined by cancer patients and oncologists: Are they influenced by depression? General Hospital Psychiatry, 29(6), 555–561.CrossRefPubMed
Metagegevens
Titel
How do patients interpret and respond to a novel patient-reported eastern cooperative oncology group performance status (ECOG)?
Auteurs
Rebecca Fillipo
Thomas W. Leblanc
Katelyn E. Plyler
Cara Arizmendi
Debra M. Henke
Theresa Coles
Publicatiedatum
18-06-2024
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 9/2024
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-024-03715-y

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