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Gepubliceerd in: Neuropraxis 4/2019

17-07-2019 | Artikel

Hersenactiviteit tijdens een dynamische houdingstaak bij de ziekte van Parkinson

Auteurs: Maarten R. C. van den Heuvel, Andreas Daffertshofer, Peter J. Beek, Gert Kwakkel, Erwin E. H. van Wegen

Gepubliceerd in: Neuropraxis | Uitgave 4/2019

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Samenvatting

Bij de ziekte van Parkinson zijn evenwichtsproblemen niet ongewoon. Aanvullende visuele feedback over de zwaaibewegingen van het lichaam tijdens het staan kan de prestatie op een houdingstaak verbeteren en balanstraining ondersteunen. Tegelijkertijd lijken mensen met parkinson extra afhankelijk te zijn van visuele informatie. Ze zijn daarmee mogelijk kwetsbaarder voor incongruente, oftewel onverenigbare, niet-passende, informatie. In deze studie toetsten we de hypothese dat incongruente visuele feedback leidt tot veranderingen in de aansturing vanuit sensomotorische netwerken in de hersenen. Hiervoor analyseerden we bij 24 mensen met de ziekte van Parkinson en een controlegroep van 15 gezonde deelnemers het elektro-encefalogram (EEG) tijdens het uitvoeren van een dynamische houdingstaak. Hierbij werd met het gehele lichaam ritmisch heen en weer bewogen, terwijl visuele feedback van de uitgevoerde zwaaibeweging werd verschaft. Hoewel de corticale hersenactiviteit van beide groepen niet verschilde bij congruente visuele feedback (passend bij de uitgevoerde zwaaibeweging), was dat wel het geval voor incongruente visuele feedback. De parkinsongroep vertoonde significant meer bètamodulatie dan de controlegroep in de primaire motorische schors, en significant meer alfamodulatie in de primaire visuele schors. Dit ging gepaard met minder aanpassingen in het bewegingspatroon. Deze bevindingen ondersteunen het idee dat bèta-modulatie een uiting is van corticale controle van (ritmisch) bewegingsgedrag, en mogelijk een belangrijke factor bij motorische adaptatie. Daarnaast sluiten de resultaten aan bij het idee dat de parkinsongroep sterker afhankelijk is van congruente informatie dan gezonde personen.
Literatuur
1.
go back to reference Schoneburg B, Mancini M, Horak FB, Nutt JG. Framework for understanding balance dysfunction in Parkinson’s disease. Mov Disord. 2013;28:1474–82. CrossRefPubMedPubMedCentral Schoneburg B, Mancini M, Horak FB, Nutt JG. Framework for understanding balance dysfunction in Parkinson’s disease. Mov Disord. 2013;28:1474–82. CrossRefPubMedPubMedCentral
3.
go back to reference Woollacott M, Shumway-Cook A. Attention and the control of posture and gait: A review of an emerging area of research. Gait Posture. 2002;16:1–14. CrossRefPubMed Woollacott M, Shumway-Cook A. Attention and the control of posture and gait: A review of an emerging area of research. Gait Posture. 2002;16:1–14. CrossRefPubMed
4.
go back to reference Maki BE, McIlroy WE. Cognitive demands and cortical control of human balance-recovery reactions. J Neural Transm. 2007;114:1279–96. CrossRefPubMed Maki BE, McIlroy WE. Cognitive demands and cortical control of human balance-recovery reactions. J Neural Transm. 2007;114:1279–96. CrossRefPubMed
5.
go back to reference Morris ME, Iansek R, Kirkwood B. A randomized controlled trial of movement strategies compared with exercise for people with Parkinson’s disease. Mov Disord. 2009;24:64–71. CrossRefPubMed Morris ME, Iansek R, Kirkwood B. A randomized controlled trial of movement strategies compared with exercise for people with Parkinson’s disease. Mov Disord. 2009;24:64–71. CrossRefPubMed
7.
go back to reference Heuvel MRC van den, Daffertshofer A, Beek PJ, Kwakkel G, Wegen EEH van. The effects of visual feedback during a rhythmic weight-shifting task in patients with Parkinson’s disease. Gait Posture. 2016;48:140–5. CrossRefPubMed Heuvel MRC van den, Daffertshofer A, Beek PJ, Kwakkel G, Wegen EEH van. The effects of visual feedback during a rhythmic weight-shifting task in patients with Parkinson’s disease. Gait Posture. 2016;48:140–5. CrossRefPubMed
8.
go back to reference Dockx K, Bekkers EM, Bergh V van den, Ginis P, Rochester L, Hausdorff JM, et al. Virtual reality for rehabilitation in Parkinson’s disease. Cochrane Database Syst Rev. 2016;12:CD10760. PubMed Dockx K, Bekkers EM, Bergh V van den, Ginis P, Rochester L, Hausdorff JM, et al. Virtual reality for rehabilitation in Parkinson’s disease. Cochrane Database Syst Rev. 2016;12:CD10760. PubMed
9.
go back to reference Garcia-Agundez A, Folkerts A‑K, Konrad R, Caserman P, Tregel T, Goosses M, et al. Recent advances in rehabilitation for Parkinson’s disease with exergames: A systematic review. J Neuroeng Rehabil. 2019;16:17. CrossRefPubMedPubMedCentral Garcia-Agundez A, Folkerts A‑K, Konrad R, Caserman P, Tregel T, Goosses M, et al. Recent advances in rehabilitation for Parkinson’s disease with exergames: A systematic review. J Neuroeng Rehabil. 2019;16:17. CrossRefPubMedPubMedCentral
10.
go back to reference Nieuwboer A, Kwakkel G, Rochester L, Jones D, Wegen EEH van, Willems AM, et al. Cueing training in the home improves gait-related mobility in Parkinson’s disease: The RESCUE trial. J Neurol Neurosurg Psychiatry. 2007;78:134. CrossRefPubMed Nieuwboer A, Kwakkel G, Rochester L, Jones D, Wegen EEH van, Willems AM, et al. Cueing training in the home improves gait-related mobility in Parkinson’s disease: The RESCUE trial. J Neurol Neurosurg Psychiatry. 2007;78:134. CrossRefPubMed
11.
go back to reference Rubinstein TC, Giladi N, Hausdorff JM. The power of cueing to circumvent dopamine deficits: A review of physical therapy treatment of gait disturbances in Parkinson’s disease. Mov Disord. 2002;17:1148–60. CrossRefPubMed Rubinstein TC, Giladi N, Hausdorff JM. The power of cueing to circumvent dopamine deficits: A review of physical therapy treatment of gait disturbances in Parkinson’s disease. Mov Disord. 2002;17:1148–60. CrossRefPubMed
12.
go back to reference Barry G, Galna B, Rochester L. The role of exergaming in Parkinson’s disease rehabilitation: A systematic review of the evidence. J Neuroeng Rehabil. 2014;11:33. CrossRefPubMedPubMedCentral Barry G, Galna B, Rochester L. The role of exergaming in Parkinson’s disease rehabilitation: A systematic review of the evidence. J Neuroeng Rehabil. 2014;11:33. CrossRefPubMedPubMedCentral
13.
go back to reference Mirelman A, Maidan I, Deutsch JE. Virtual reality and motor imagery: Promising tools for assessment and therapy in Parkinson’s disease. Mov Disord. 2013;28:1597–608. CrossRefPubMed Mirelman A, Maidan I, Deutsch JE. Virtual reality and motor imagery: Promising tools for assessment and therapy in Parkinson’s disease. Mov Disord. 2013;28:1597–608. CrossRefPubMed
14.
go back to reference Tomlinson CL, Patel S, Meek C, Herd CP, Clarke CE, Stowe R, et al. Physiotherapy versus placebo or no intervention in Parkinson’s disease. Cochrane Database Syst Rev. 2013;9:CD2817. Tomlinson CL, Patel S, Meek C, Herd CP, Clarke CE, Stowe R, et al. Physiotherapy versus placebo or no intervention in Parkinson’s disease. Cochrane Database Syst Rev. 2013;9:CD2817.
15.
go back to reference Heuvel MRC van den, Kwakkel G, Beek PJ, Berendse HW, Daffertshofer A, Wegen EEH van. Effects of augmented visual feedback during balance training in Parkinson’s disease: A pilot randomized clinical trial. Parkinsonism Relat Disord. 2014;20:1352–8. CrossRefPubMed Heuvel MRC van den, Kwakkel G, Beek PJ, Berendse HW, Daffertshofer A, Wegen EEH van. Effects of augmented visual feedback during balance training in Parkinson’s disease: A pilot randomized clinical trial. Parkinsonism Relat Disord. 2014;20:1352–8. CrossRefPubMed
16.
go back to reference Brown P. Abnormal oscillatory synchronisation in the motor system leads to impaired movement. Curr Opin Neurobiol. 2007;17:656–64. CrossRefPubMed Brown P. Abnormal oscillatory synchronisation in the motor system leads to impaired movement. Curr Opin Neurobiol. 2007;17:656–64. CrossRefPubMed
17.
go back to reference Jenkinson N, Brown P. New insights into the relationship between dopamine, beta oscillations and motor function. Trends Neurosci. 2011;34:611–8. CrossRefPubMed Jenkinson N, Brown P. New insights into the relationship between dopamine, beta oscillations and motor function. Trends Neurosci. 2011;34:611–8. CrossRefPubMed
18.
go back to reference Neumann W‑J, Degen K, Schneider G‑H, Brücke C, Huebl J, Brown P, et al. Subthalamic synchronized oscillatory activity correlates with motor impairment in patients with Parkinson’s disease. Mov Disord. 2016;31:1748–51. CrossRefPubMedPubMedCentral Neumann W‑J, Degen K, Schneider G‑H, Brücke C, Huebl J, Brown P, et al. Subthalamic synchronized oscillatory activity correlates with motor impairment in patients with Parkinson’s disease. Mov Disord. 2016;31:1748–51. CrossRefPubMedPubMedCentral
19.
go back to reference Kühn AA, Tsui A, Aziz T, Ray N, Brücke C, Kupsch A, et al. Pathological synchronisation in the subthalamic nucleus of patients with Parkinson’s disease relates to both bradykinesia and rigidity. Exp Neurol. 2009;215:380–7. CrossRefPubMed Kühn AA, Tsui A, Aziz T, Ray N, Brücke C, Kupsch A, et al. Pathological synchronisation in the subthalamic nucleus of patients with Parkinson’s disease relates to both bradykinesia and rigidity. Exp Neurol. 2009;215:380–7. CrossRefPubMed
20.
go back to reference Ray NJ, Jenkinson N, Wang S, Holland P, Brittain JS, Joint C, et al. Local field potential beta activity in the subthalamic nucleus of patients with Parkinson’s disease is associated with improvements in bradykinesia after dopamine and deep brain stimulation. Exp Neurol. 2008;213:108–13. CrossRefPubMed Ray NJ, Jenkinson N, Wang S, Holland P, Brittain JS, Joint C, et al. Local field potential beta activity in the subthalamic nucleus of patients with Parkinson’s disease is associated with improvements in bradykinesia after dopamine and deep brain stimulation. Exp Neurol. 2008;213:108–13. CrossRefPubMed
21.
go back to reference Oswal A, Litvak V, Sauleau P, Brown P. Beta reactivity, prospective facilitation of executive processing, and its dependence on dopaminergic therapy in Parkinson’s disease. J Neurosci. 2012;32:9909–16. CrossRefPubMedPubMedCentral Oswal A, Litvak V, Sauleau P, Brown P. Beta reactivity, prospective facilitation of executive processing, and its dependence on dopaminergic therapy in Parkinson’s disease. J Neurosci. 2012;32:9909–16. CrossRefPubMedPubMedCentral
22.
go back to reference Tan H, Jenkinson N, Brown P. Dynamic neural correlates of motor error monitoring and adaptation during trial-to-trial learning. J Neurosci. 2014;34:5678–88. CrossRefPubMedPubMedCentral Tan H, Jenkinson N, Brown P. Dynamic neural correlates of motor error monitoring and adaptation during trial-to-trial learning. J Neurosci. 2014;34:5678–88. CrossRefPubMedPubMedCentral
23.
go back to reference Caudron S, Guerraz M, Eusebio A, Gros J‑P, Azulay JP, Vaugoyeau M. Evaluation of a visual biofeedback on the postural control in Parkinson’s disease. Neurophysiol Clin. 2014;44:77–86. CrossRefPubMed Caudron S, Guerraz M, Eusebio A, Gros J‑P, Azulay JP, Vaugoyeau M. Evaluation of a visual biofeedback on the postural control in Parkinson’s disease. Neurophysiol Clin. 2014;44:77–86. CrossRefPubMed
24.
go back to reference Vaugoyeau M, Azulay J‑P. Role of sensory information in the control of postural orientation in Parkinson’s disease. J Neurol Sci. 2010;289:66–8. CrossRefPubMed Vaugoyeau M, Azulay J‑P. Role of sensory information in the control of postural orientation in Parkinson’s disease. J Neurol Sci. 2010;289:66–8. CrossRefPubMed
25.
go back to reference Tan H, Wade C, Brown P. Post-movement beta activity in sensorimotor cortex indexes confidence in the estimations from internal models. J Neurosci. 2016;36:1516–28. CrossRefPubMedPubMedCentral Tan H, Wade C, Brown P. Post-movement beta activity in sensorimotor cortex indexes confidence in the estimations from internal models. J Neurosci. 2016;36:1516–28. CrossRefPubMedPubMedCentral
26.
go back to reference Gibb WR, Lees AJ. The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson’s disease. J Neurol Neurosurg Psychiatry. 1988;51:745–52. CrossRefPubMedPubMedCentral Gibb WR, Lees AJ. The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson’s disease. J Neurol Neurosurg Psychiatry. 1988;51:745–52. CrossRefPubMedPubMedCentral
27.
go back to reference Mardia KV, Jupp PE. Directional statistics. Chichester: Wiley; 2000. Mardia KV, Jupp PE. Directional statistics. Chichester: Wiley; 2000.
29.
go back to reference Heuvel MRC van den, Wegen EEH van, Beek PJ, Kwakkel G, Daffertshofer A. Incongruent visual feedback during a postural task enhances cortical alpha and beta modulation in patients with Parkinson’s disease. Clin Neurophysiol. 2018;129:1357–65. CrossRefPubMed Heuvel MRC van den, Wegen EEH van, Beek PJ, Kwakkel G, Daffertshofer A. Incongruent visual feedback during a postural task enhances cortical alpha and beta modulation in patients with Parkinson’s disease. Clin Neurophysiol. 2018;129:1357–65. CrossRefPubMed
30.
go back to reference Van Veen BD, Drongelen W van, Yuchtman M, Suzuki A. Localization of brain electrical activity via linearly constrained minimum variance spatial filtering. IEEE Trans Biomed Eng. 1997;44:867–80. CrossRefPubMed Van Veen BD, Drongelen W van, Yuchtman M, Suzuki A. Localization of brain electrical activity via linearly constrained minimum variance spatial filtering. IEEE Trans Biomed Eng. 1997;44:867–80. CrossRefPubMed
31.
go back to reference Hillebrand A, Barnes GR. The use of anatomical constraints with MEG beamformers. Neuroimage. 2003;20:2302–13. CrossRefPubMed Hillebrand A, Barnes GR. The use of anatomical constraints with MEG beamformers. Neuroimage. 2003;20:2302–13. CrossRefPubMed
32.
go back to reference Lim I, Wegen EEH van, Jones D, Rochester L, Nieuwboer A, Willems A‑M, et al. Does cueing training improve physical activity in patients with Parkinson’s disease? Neurorehabil Neural Repair. 2010;24:469–77. CrossRefPubMed Lim I, Wegen EEH van, Jones D, Rochester L, Nieuwboer A, Willems A‑M, et al. Does cueing training improve physical activity in patients with Parkinson’s disease? Neurorehabil Neural Repair. 2010;24:469–77. CrossRefPubMed
34.
go back to reference Pfurtscheller G, Lopes da Silva FH. Event-related EEG/MEG synchronization and desynchronization: Basic principles. Clin Neurophysiol. 1999;110:1842–57. CrossRefPubMed Pfurtscheller G, Lopes da Silva FH. Event-related EEG/MEG synchronization and desynchronization: Basic principles. Clin Neurophysiol. 1999;110:1842–57. CrossRefPubMed
36.
go back to reference Gwin JT, Gramann K, Makeig S, Ferris DP. Electrocortical activity is coupled to gait cycle phase during treadmill walking. Neuroimage. 2011;54:1289–96. CrossRefPubMed Gwin JT, Gramann K, Makeig S, Ferris DP. Electrocortical activity is coupled to gait cycle phase during treadmill walking. Neuroimage. 2011;54:1289–96. CrossRefPubMed
37.
go back to reference Shadmehr R, Smith MA, Krakauer JW. Error correction, sensory prediction, and adaptation in motor control. Annu Rev Neurosci. 2010;33:89–108. CrossRefPubMed Shadmehr R, Smith MA, Krakauer JW. Error correction, sensory prediction, and adaptation in motor control. Annu Rev Neurosci. 2010;33:89–108. CrossRefPubMed
38.
go back to reference McKay JL, Lang KC, Ting LH, Hackney ME. Impaired set shifting is associated with previous falls in individuals with and without Parkinson’s disease. Gait Posture. 2018;62:220–6. CrossRefPubMedPubMedCentral McKay JL, Lang KC, Ting LH, Hackney ME. Impaired set shifting is associated with previous falls in individuals with and without Parkinson’s disease. Gait Posture. 2018;62:220–6. CrossRefPubMedPubMedCentral
39.
go back to reference Pfurtscheller G, Neuper C, Mohl W. Event-related desynchronization (ERD) during visual processing. Int J Psychophysiol. 1994;16:147–53. CrossRefPubMed Pfurtscheller G, Neuper C, Mohl W. Event-related desynchronization (ERD) during visual processing. Int J Psychophysiol. 1994;16:147–53. CrossRefPubMed
40.
go back to reference Brittain JS, Brown P. Oscillations and the basal ganglia: Motor control and beyond. Neuroimage. 2014;85(Pt 2):637–47. CrossRefPubMed Brittain JS, Brown P. Oscillations and the basal ganglia: Motor control and beyond. Neuroimage. 2014;85(Pt 2):637–47. CrossRefPubMed
Metagegevens
Titel
Hersenactiviteit tijdens een dynamische houdingstaak bij de ziekte van Parkinson
Auteurs
Maarten R. C. van den Heuvel
Andreas Daffertshofer
Peter J. Beek
Gert Kwakkel
Erwin E. H. van Wegen
Publicatiedatum
17-07-2019
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Neuropraxis / Uitgave 4/2019
Print ISSN: 1387-5817
Elektronisch ISSN: 1876-5785
DOI
https://doi.org/10.1007/s12474-019-00227-1