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Gepubliceerd in: Journal of Autism and Developmental Disorders 6/2012

01-06-2012 | Original Paper

Heavy Metal in Children’s Tooth Enamel: Related to Autism and Disruptive Behaviors?

Auteurs: Maryam M. Abdullah, Agnes R. Ly, Wendy A. Goldberg, K. Alison Clarke-Stewart, John V. Dudgeon, Christopher G. Mull, Tony J. Chan, Erin E. Kent, Andrew Z. Mason, Jonathon E. Ericson

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 6/2012

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Abstract

To examine possible links between neurotoxicant exposure and neuropsychological disorders and child behavior, relative concentrations of lead, mercury, and manganese were examined in prenatal and postnatal enamel regions of deciduous teeth from children with Autism Spectrum Disorders (ASDs), high levels of disruptive behavior (HDB), and typically developing (TD) children. Using laser ablation inductively coupled plasma mass spectrometry, we found no significant differences in levels of these neurotoxicants for children with ASDs compared with TD children, but there was marginal significance indicating that children with ASDs have lower manganese levels. No significant differences emerged between children with HDB and TD children. The current findings challenge the notion that perinatal heavy metal exposure is a major contributor to the development of ASDs and HDB.
Literatuur
go back to reference Adams, J. B., Romdalvik, J., Ramanujam, V. M. S., & Legator, M. S. (2007). Mercury, lead, and zinc in baby teeth of children with autism versus controls. Journal of Toxicology and Environmental Health. Part A, 70(12), 1046–1051. doi:10.1080/15287390601172080.PubMedCrossRef Adams, J. B., Romdalvik, J., Ramanujam, V. M. S., & Legator, M. S. (2007). Mercury, lead, and zinc in baby teeth of children with autism versus controls. Journal of Toxicology and Environmental Health. Part A, 70(12), 1046–1051. doi:10.​1080/​1528739060117208​0.PubMedCrossRef
go back to reference American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed. text revision). Washington, DC: Author. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed. text revision). Washington, DC: Author.
go back to reference Ash, M. M., & Nelson, S. J. (2003). Wheeler’s dental anatomy, physiology and occlusion (8th ed.). St Louis: Elsevier. Ash, M. M., & Nelson, S. J. (2003). Wheeler’s dental anatomy, physiology and occlusion (8th ed.). St Louis: Elsevier.
go back to reference Bass, D. A., Hickock, D., Quig, D., & Urek, K. (2001). Trace element analysis in hair: Factors determining accuracy, precision, and reliability. Alternative Medicine Review, 6, 472–481.PubMed Bass, D. A., Hickock, D., Quig, D., & Urek, K. (2001). Trace element analysis in hair: Factors determining accuracy, precision, and reliability. Alternative Medicine Review, 6, 472–481.PubMed
go back to reference Bouchard, M., Laforest, F., Vandelac, L., Bellinger, D., & Mergler, D. (2007). Hair manganese and hyperactive behaviors: Pilot study of school-age children exposed through tap water. Environmental Health Perspectives, 115(1), 122–127. doi:10.1289/ehp.9504.PubMedCrossRef Bouchard, M., Laforest, F., Vandelac, L., Bellinger, D., & Mergler, D. (2007). Hair manganese and hyperactive behaviors: Pilot study of school-age children exposed through tap water. Environmental Health Perspectives, 115(1), 122–127. doi:10.​1289/​ehp.​9504.PubMedCrossRef
go back to reference Braun, J. M., Kahn, R. S., Froehlich, T., Auinger, P., & Lanphear, B. P. (2006). Exposures to environmental toxicants and attention deficit hyperactivity disorder in U.S. children. Environmental Health Perspectives, 114(12), 1904–1909. doi:10.1289/ehp.9478.PubMed Braun, J. M., Kahn, R. S., Froehlich, T., Auinger, P., & Lanphear, B. P. (2006). Exposures to environmental toxicants and attention deficit hyperactivity disorder in U.S. children. Environmental Health Perspectives, 114(12), 1904–1909. doi:10.​1289/​ehp.​9478.PubMed
go back to reference Cohen, J. (1988). Statistical power for the behavioral sciences. Hillsdale, NJ: Erlbaum. Cohen, J. (1988). Statistical power for the behavioral sciences. Hillsdale, NJ: Erlbaum.
go back to reference Davidson, P. W., Myers, G. J., Cox, C., Axtell, C., Shamlaye, C., Sloane-Reeves, J., et al. (1998). Effects of prenatal and postnatal methylmercury exposure from fish consumption on neurodevelopment: Outcomes at 66 months of age in the Seychelles Child Development Study. Journal of the American Medical Association, 280(8), 701–707. doi:10.1001/jama.280.8.701.PubMedCrossRef Davidson, P. W., Myers, G. J., Cox, C., Axtell, C., Shamlaye, C., Sloane-Reeves, J., et al. (1998). Effects of prenatal and postnatal methylmercury exposure from fish consumption on neurodevelopment: Outcomes at 66 months of age in the Seychelles Child Development Study. Journal of the American Medical Association, 280(8), 701–707. doi:10.​1001/​jama.​280.​8.​701.PubMedCrossRef
go back to reference DeSoto, M. C., & Hitlan, R. T. (2010). Sorting out the spinning of autism: Heavy metals and the question of incidence. Acta Neurobiologiae Experimentalis, 70, 165–176.PubMedCrossRef DeSoto, M. C., & Hitlan, R. T. (2010). Sorting out the spinning of autism: Heavy metals and the question of incidence. Acta Neurobiologiae Experimentalis, 70, 165–176.PubMedCrossRef
go back to reference Ericson, J. E., Crinella, F. M., Clarke-Stewart, K. A., Allhusen, V. D., Chan, T., & Robertson, R. T. (2007). Prenatal manganese levels linked to childhood behavioral disinhibition. Neurotoxicology and Teratology, 29(2), 181–187. doi:10.1016/j.ntt.2006.09.020.PubMedCrossRef Ericson, J. E., Crinella, F. M., Clarke-Stewart, K. A., Allhusen, V. D., Chan, T., & Robertson, R. T. (2007). Prenatal manganese levels linked to childhood behavioral disinhibition. Neurotoxicology and Teratology, 29(2), 181–187. doi:10.​1016/​j.​ntt.​2006.​09.​020.PubMedCrossRef
go back to reference Farmer, J. G., MacKenzie, A. B., & Moody, G. H. (2006). Human teeth as historical biomonitors of environmental and dietary lead: Some lessons from isotopic studies of 19th and 20th century archival material. Environmental Geochemistry and Health, 28, 421–430. doi:10.1007/s10653-006-9041-5.PubMedCrossRef Farmer, J. G., MacKenzie, A. B., & Moody, G. H. (2006). Human teeth as historical biomonitors of environmental and dietary lead: Some lessons from isotopic studies of 19th and 20th century archival material. Environmental Geochemistry and Health, 28, 421–430. doi:10.​1007/​s10653-006-9041-5.PubMedCrossRef
go back to reference Fido, A., Dashti, H., & Al-Saad, S. (2002). Biological correlates of childhood autism: Trace elements. Trace Elements and Electrolytes, 19, 205–208. Fido, A., Dashti, H., & Al-Saad, S. (2002). Biological correlates of childhood autism: Trace elements. Trace Elements and Electrolytes, 19, 205–208.
go back to reference Froehlich, T. E., Lanphear, B. P., Auinger, P., Hornung, R., Epstein, J. N., Braun, J., et al. (2009). Association of tobacco and lead exposures with attention-deficit/hyperactivity disorder. Pediatrics, 124, e1054–e1063. doi:10.1542/peds.2009-0738.PubMedCrossRef Froehlich, T. E., Lanphear, B. P., Auinger, P., Hornung, R., Epstein, J. N., Braun, J., et al. (2009). Association of tobacco and lead exposures with attention-deficit/hyperactivity disorder. Pediatrics, 124, e1054–e1063. doi:10.​1542/​peds.​2009-0738.PubMedCrossRef
go back to reference Gentile, P. S., Trentalange, M. J., Zamichek, W., & Coleman, M. (1983). Trace elements in the hair of autistic and control children. Journal of Autism and Developmental Disorders, 13(2), 205–206. doi:10.1007/BF01531820.PubMedCrossRef Gentile, P. S., Trentalange, M. J., Zamichek, W., & Coleman, M. (1983). Trace elements in the hair of autistic and control children. Journal of Autism and Developmental Disorders, 13(2), 205–206. doi:10.​1007/​BF01531820.PubMedCrossRef
go back to reference Heron, J., Golding, J., & the ALSPAC Study Team. (2004). Thimerosal exposure in infants and developmental disorders: A prospective cohort study in the United Kingdom does not support a causal association. Pediatrics, 114, 577–583. doi:10.1542/peds.2003-1176-L.PubMedCrossRef Heron, J., Golding, J., & the ALSPAC Study Team. (2004). Thimerosal exposure in infants and developmental disorders: A prospective cohort study in the United Kingdom does not support a causal association. Pediatrics, 114, 577–583. doi:10.​1542/​peds.​2003-1176-L.PubMedCrossRef
go back to reference Hertz-Picciotto, I., Green, P. G., Delwiche, L., Hansen, R., Walker, C., & Pessah, I. N. (2010). Blood mercury concentrations in CHARGE Study children with and without autism. Environmental Health Perspectives, 118(1), 161–166. doi:10.1289/ehp.0900736.PubMed Hertz-Picciotto, I., Green, P. G., Delwiche, L., Hansen, R., Walker, C., & Pessah, I. N. (2010). Blood mercury concentrations in CHARGE Study children with and without autism. Environmental Health Perspectives, 118(1), 161–166. doi:10.​1289/​ehp.​0900736.PubMed
go back to reference Kang, D., Amarasiriwardena, D., & Goodman, A. H. (2004). Application of laser ablation–inductively coupled plasma-mass spectrometry (LA–ICP–MS) to investigate trace metal spatial distributions in human tooth enamel and dentine growth layers and pulp. Analytical and Bioanalytical Chemistry, 378, 1608–1615. doi:10.1007/s00216-004-2504-6.PubMedCrossRef Kang, D., Amarasiriwardena, D., & Goodman, A. H. (2004). Application of laser ablation–inductively coupled plasma-mass spectrometry (LA–ICP–MS) to investigate trace metal spatial distributions in human tooth enamel and dentine growth layers and pulp. Analytical and Bioanalytical Chemistry, 378, 1608–1615. doi:10.​1007/​s00216-004-2504-6.PubMedCrossRef
go back to reference Kogan, M. D., Blumberg, S. J., Schieve, L. A., Boyle, C. A., Perrin, J. M., Ghandour, R. M., et al. (2009). Prevalence of parent-reported diagnosis of autism spectrum disorder among children in the US, 2007. Pediatrics, 124, 1395–1403. doi:10.1542/peds.2009-1522.PubMedCrossRef Kogan, M. D., Blumberg, S. J., Schieve, L. A., Boyle, C. A., Perrin, J. M., Ghandour, R. M., et al. (2009). Prevalence of parent-reported diagnosis of autism spectrum disorder among children in the US, 2007. Pediatrics, 124, 1395–1403. doi:10.​1542/​peds.​2009-1522.PubMedCrossRef
go back to reference Lakshmi Priya, M. D., & Geetha, A. (2010) Level of trace elements (copper, zinc, magnesium and selenium) and toxic elements (lead and mercury) in the hair and nail of children with autism. Biological Trace Element Research. doi:10.1007/s12011-010-8766-2. Lakshmi Priya, M. D., & Geetha, A. (2010) Level of trace elements (copper, zinc, magnesium and selenium) and toxic elements (lead and mercury) in the hair and nail of children with autism. Biological Trace Element Research. doi:10.​1007/​s12011-010-8766-2.
go back to reference Landrigan, P. J., Trasande, L., Thorpe, L. E., Gwynn, C., Lioy, P. J., D’Alton, M. E., et al. (2006). The National Children’s Study: A 21-year prospective study of 100,000 American children. Pediatrics, 118(5), 2173–2186. doi:10.1542/peds.2006-0360.PubMedCrossRef Landrigan, P. J., Trasande, L., Thorpe, L. E., Gwynn, C., Lioy, P. J., D’Alton, M. E., et al. (2006). The National Children’s Study: A 21-year prospective study of 100,000 American children. Pediatrics, 118(5), 2173–2186. doi:10.​1542/​peds.​2006-0360.PubMedCrossRef
go back to reference Lewandowski, T. A. (2011). Evolving understanding of the relationship between mercury exposure and autism. In L. I. Simeonov, M. V. Kochubovski, & B. G. Simeonova (Eds.), Environmental heavy metal pollution and effects on child mental development (Vol. 1, pp. 65–84). Dordrecht: Springer Netherlands. Retrieved from http://www.springerlink.com/content/l4n65m6600547417/. Lewandowski, T. A. (2011). Evolving understanding of the relationship between mercury exposure and autism. In L. I. Simeonov, M. V. Kochubovski, & B. G. Simeonova (Eds.), Environmental heavy metal pollution and effects on child mental development (Vol. 1, pp. 65–84). Dordrecht: Springer Netherlands. Retrieved from http://​www.​springerlink.​com/​content/​l4n65m6600547417​/​.
go back to reference Lord, C., Rutter, M., DiLavore, P. C., & Risi, S. (1999). Autism diagnostic observation schedule. Los Angeles, CA: Western Psychological Services. Lord, C., Rutter, M., DiLavore, P. C., & Risi, S. (1999). Autism diagnostic observation schedule. Los Angeles, CA: Western Psychological Services.
go back to reference Madsen, K. M., Hviid, A., Vestergaard, M., Schendel, D., Wohlfahrt, J., Thorsen, P., et al. (2002). A population-based study of measles, mumps, and rubella vaccination and autism. New England Journal of Medicine, 347, 1477–1482.PubMedCrossRef Madsen, K. M., Hviid, A., Vestergaard, M., Schendel, D., Wohlfahrt, J., Thorsen, P., et al. (2002). A population-based study of measles, mumps, and rubella vaccination and autism. New England Journal of Medicine, 347, 1477–1482.PubMedCrossRef
go back to reference Menezes-Filho, J. A., de Novaes, C. O., Moreira, J. C., Sarcinelli, P. N., & Mergler, D. (2011). Elevated manganese and cognitive performance in school-aged children and their mothers. Environmental Research, 111, 156–163. doi:16/j.envres.2010.09.006.PubMedCrossRef Menezes-Filho, J. A., de Novaes, C. O., Moreira, J. C., Sarcinelli, P. N., & Mergler, D. (2011). Elevated manganese and cognitive performance in school-aged children and their mothers. Environmental Research, 111, 156–163. doi:16/​j.​envres.​2010.​09.​006.PubMedCrossRef
go back to reference Nanci, A. (2008). Ten Cate’s oral histology: Development, structure, and function (7th ed.). St. Louis: Mosby. Nanci, A. (2008). Ten Cate’s oral histology: Development, structure, and function (7th ed.). St. Louis: Mosby.
go back to reference Neff, H., & Dudgeon, J. V. (2006). LA-ICP-MS analysis of ceramics and ceramic raw materials from the Gila River Indian community, Arizona, (Research Report: Institute for Integrated Research in Materials, Environments, and Society). Long Beach, CA: California State University, Long Beach. Neff, H., & Dudgeon, J. V. (2006). LA-ICP-MS analysis of ceramics and ceramic raw materials from the Gila River Indian community, Arizona, (Research Report: Institute for Integrated Research in Materials, Environments, and Society). Long Beach, CA: California State University, Long Beach.
go back to reference NICHD Early Child Care Research Network. (2005). Child care and child development: Results from the NICHD Study of Early Child Care and Youth Development. New York: Guilford. NICHD Early Child Care Research Network. (2005). Child care and child development: Results from the NICHD Study of Early Child Care and Youth Development. New York: Guilford.
go back to reference Nigg, J. T., Knottnerus, G. M., Martel, M. M., Nikolas, M., Cavanagh, K., Karmaus, W., et al. (2008). Low blood lead levels associated with clinically diagnosed attention-deficit/hyperactivity disorder and mediated by weak cognitive control. Biological Psychiatry, 63(3), 325–331. doi:10.1016/j.biopsych.2007.07.013.PubMedCrossRef Nigg, J. T., Knottnerus, G. M., Martel, M. M., Nikolas, M., Cavanagh, K., Karmaus, W., et al. (2008). Low blood lead levels associated with clinically diagnosed attention-deficit/hyperactivity disorder and mediated by weak cognitive control. Biological Psychiatry, 63(3), 325–331. doi:10.​1016/​j.​biopsych.​2007.​07.​013.PubMedCrossRef
go back to reference Palmer, R. F., Blanchard, S., Stein, Z., Mandell, D., & Miller, C. (2006). Environmental mercury release, special education rates, and autism disorder: An ecological study of Texas. Health & Place, 12, 203–209. doi:16/j.healthplace.2004.11.005.CrossRef Palmer, R. F., Blanchard, S., Stein, Z., Mandell, D., & Miller, C. (2006). Environmental mercury release, special education rates, and autism disorder: An ecological study of Texas. Health & Place, 12, 203–209. doi:16/​j.​healthplace.​2004.​11.​005.CrossRef
go back to reference Pelham, W. E., Gnagy, E., Greenslade, K., & Milich, R. (1992). Teacher ratings of DSM-III-R symptoms for the disruptive behavior disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 31, 210–218.PubMedCrossRef Pelham, W. E., Gnagy, E., Greenslade, K., & Milich, R. (1992). Teacher ratings of DSM-III-R symptoms for the disruptive behavior disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 31, 210–218.PubMedCrossRef
go back to reference Pocock, S. J., Smith, M., & Baghurst, P. (1994). Environmental lead and children’s intelligence: A systematic review of the epidemiological evidence. British Medical Journal, 309, 1189–1197.PubMedCrossRef Pocock, S. J., Smith, M., & Baghurst, P. (1994). Environmental lead and children’s intelligence: A systematic review of the epidemiological evidence. British Medical Journal, 309, 1189–1197.PubMedCrossRef
go back to reference Ris, M. D., Dietrich, K. N., Succop, P. A., Berger, O. G., & Bornschein, R. L. (2004). Early exposure to lead and neuropsychological outcome in adolescence. Journal of the International Neuropsychological Society, 10, 261–270. doi:10.1017/S1355617704102154.PubMedCrossRef Ris, M. D., Dietrich, K. N., Succop, P. A., Berger, O. G., & Bornschein, R. L. (2004). Early exposure to lead and neuropsychological outcome in adolescence. Journal of the International Neuropsychological Society, 10, 261–270. doi:10.​1017/​S135561770410215​4.PubMedCrossRef
go back to reference Rodier, P. M. (1995). Developing brain as a target of toxicity. Environmental Health Perspectives, 103(6), 73–76.PubMedCrossRef Rodier, P. M. (1995). Developing brain as a target of toxicity. Environmental Health Perspectives, 103(6), 73–76.PubMedCrossRef
go back to reference Rutter, M., Le Couteur, A., & Lord, C. (2003). ADI-R: The autism diagnostic interview-revised. Los Angeles, CA: Western Psychological Services. Rutter, M., Le Couteur, A., & Lord, C. (2003). ADI-R: The autism diagnostic interview-revised. Los Angeles, CA: Western Psychological Services.
go back to reference Soden, S. E., Lowry, J. A., Garrison, C. B., & Wasserman, G. S. (2007). 24-hour provoked urine excretion test for heavy metals in children with autism and typically developing controls, a pilot study. Clinical Toxicology, 45, 476–481. doi:10.1080/15563650701338195.PubMedCrossRef Soden, S. E., Lowry, J. A., Garrison, C. B., & Wasserman, G. S. (2007). 24-hour provoked urine excretion test for heavy metals in children with autism and typically developing controls, a pilot study. Clinical Toxicology, 45, 476–481. doi:10.​1080/​1556365070133819​5.PubMedCrossRef
go back to reference Speakman, R. J., & Neff, H. (2005). Laser ablation ICP-MS in archaeological research. Albuquerque, NM: University of New Mexico Press. Speakman, R. J., & Neff, H. (2005). Laser ablation ICP-MS in archaeological research. Albuquerque, NM: University of New Mexico Press.
go back to reference Tvinnereim, H. M., Eide, R., Fosse, G., Wesenberg, G. R., Szøke, J., & Banoczy, J. (1996). Trace elements in primary teeth from six areas in Hungary. International Journal of Environmental Studies, 50, 267–275. doi:10.1016/S0048-9697(00)00436-8.CrossRef Tvinnereim, H. M., Eide, R., Fosse, G., Wesenberg, G. R., Szøke, J., & Banoczy, J. (1996). Trace elements in primary teeth from six areas in Hungary. International Journal of Environmental Studies, 50, 267–275. doi:10.​1016/​S0048-9697(00)00436-8.CrossRef
go back to reference Uryu, T., Yoshinaga, J., Yanagisawa, Y., Endo, M., & Takahashi, J. (2003). Analysis of lead in tooth enamel by laser ablation-inductively coupled plasma-mass spectrometry. Analytical Sciences: The International Journal of the Japan Society for Analytical Chemistry, 19(10), 1413–1416.CrossRef Uryu, T., Yoshinaga, J., Yanagisawa, Y., Endo, M., & Takahashi, J. (2003). Analysis of lead in tooth enamel by laser ablation-inductively coupled plasma-mass spectrometry. Analytical Sciences: The International Journal of the Japan Society for Analytical Chemistry, 19(10), 1413–1416.CrossRef
go back to reference Wang, H. L., Chen, X. T., Yang, B., Ma, F. L., Wang, S., Tang, M. L., et al. (2008). Case–control study of blood lead levels and attention deficit hyperactivity disorder in chinese children. Environmental Health Perspectives, 116(10), 1401–1406. doi:10.1289/ehp.11400.PubMedCrossRef Wang, H. L., Chen, X. T., Yang, B., Ma, F. L., Wang, S., Tang, M. L., et al. (2008). Case–control study of blood lead levels and attention deficit hyperactivity disorder in chinese children. Environmental Health Perspectives, 116(10), 1401–1406. doi:10.​1289/​ehp.​11400.PubMedCrossRef
go back to reference Wasserman, G. A., Liu, X., Parvez, F., Ahsan, H., Levy, D., Factor-Litvak, P., et al. (2006). Water manganese exposure and children’s intellectual function in Araihazar, Bangladesh. Environmental Health Perspectives, 114, 124–129. doi:10.1289/ehp.8030.PubMed Wasserman, G. A., Liu, X., Parvez, F., Ahsan, H., Levy, D., Factor-Litvak, P., et al. (2006). Water manganese exposure and children’s intellectual function in Araihazar, Bangladesh. Environmental Health Perspectives, 114, 124–129. doi:10.​1289/​ehp.​8030.PubMed
go back to reference Windham, G. C., Zhang, L., Gunier, R., Croen, L. A., & Grether, J. K. (2006). Autism spectrum disorders in relation to distribution of hazardous air pollutants in the San Francisco Bay area. Environmental Health Perspectives, 114, 1438–1444.PubMedCrossRef Windham, G. C., Zhang, L., Gunier, R., Croen, L. A., & Grether, J. K. (2006). Autism spectrum disorders in relation to distribution of hazardous air pollutants in the San Francisco Bay area. Environmental Health Perspectives, 114, 1438–1444.PubMedCrossRef
go back to reference Wright, R. O., Amarasiriwardena, C., Woolf, A. D., Jim, R., & Bellinger, D. C. (2006). Neuropsychological correlates of hair arsenic, manganese, and cadmium levels in school-age children residing near a hazardous waste site. Neurotoxicology, 27, 210–216. doi:16/j.neuro.2005.10.001.PubMedCrossRef Wright, R. O., Amarasiriwardena, C., Woolf, A. D., Jim, R., & Bellinger, D. C. (2006). Neuropsychological correlates of hair arsenic, manganese, and cadmium levels in school-age children residing near a hazardous waste site. Neurotoxicology, 27, 210–216. doi:16/​j.​neuro.​2005.​10.​001.PubMedCrossRef
Metagegevens
Titel
Heavy Metal in Children’s Tooth Enamel: Related to Autism and Disruptive Behaviors?
Auteurs
Maryam M. Abdullah
Agnes R. Ly
Wendy A. Goldberg
K. Alison Clarke-Stewart
John V. Dudgeon
Christopher G. Mull
Tony J. Chan
Erin E. Kent
Andrew Z. Mason
Jonathon E. Ericson
Publicatiedatum
01-06-2012
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 6/2012
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-011-1318-6

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