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01-03-2013 | Brief Communication | Uitgave 2/2013

Quality of Life Research 2/2013

Health Utilities Index Mark 3 (HUI3) demonstrated construct validity in a Nigerian population with hypertension

Tijdschrift:
Quality of Life Research > Uitgave 2/2013
Auteurs:
Obinna Ikechukwu Ekwunife, Cletus Nze Aguwa, Nneka Uchenna Igboeli

Abstract

Purpose

This study seeks to establish the construct validity of Health Utilities Index Mark 3 (HUI3)—a health state utility measure—in a Nigerian population of hypertensive patients.

Methods

A descriptive cross-sectional study was conducted in a population of hypertensive patients in two tertiary hospitals located in South-Eastern Nigeria. A priori hypotheses were tested to establish construct validity.

Results

A total of 384 participants were interviewed. Hypertensive patients with stroke or coronary heart disease (CHD) had a lower overall utility value compared to those with hypertension alone. There was a significant difference in group means of 0.53 (95 % confidence interval of 0.44–0.62); t = 11.8, p < 0.01, between participants that had hypertension alone and participants with hypertension and stroke. Also, there was a significant difference in group means of 0.44 (95 % confidence interval of 0.34–0.56); t = 8.2, p < 0.01, between participants that had hypertension alone and participants with hypertension and CHD. Generally, there was a significant health-related quality of life deficit among patients with severe clinical variables compared to those with milder clinical variables.

Conclusion

HUI3 demonstrated constructed validity among a population of Nigerian patients with high blood pressure.

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