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Gepubliceerd in: Quality of Life Research 1/2013

01-02-2013

Health-related quality-of-life status in Veterans with spinal disorders

Auteurs: Maxwell Boakye, Ryan Moore, Maiying Kong, Stephen L. Skirboll, Robert T. Arrigo

Gepubliceerd in: Quality of Life Research | Uitgave 1/2013

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Abstract

Purpose

To measure the impact of spinal disorders on health-related quality of life (HRQOL) among Veterans, to describe demographic patterns of Veterans with spinal disorders, and to quantify HRQOL scores as they relate to demographics, medical comorbidities, pain severity, and depressive symptoms.

Methods

From 2009 to 2010, 112 lumbar and 56 cervical spinal disorder patients completed SF-12, Oswestry Disability Index, visual analog pain scale, and Beck Depression Inventory surveys. Multivariate analysis identified predictors of HRQOL, disability, and depressive symptoms.

Results

A total of 168 patients completed surveys for this study. The median age of all patients was 60. Nearly 30% of lumbar and 16% of cervical patients were aged 65 or older. Approximately 96% of patients were men. Sixty percent of patients were currently receiving or had pending disability compensation. Nearly 60% of patients were current smokers, approximately 26% reported alcoholism or intravenous drug use, and 26% self-reported post-traumatic stress disorder. The most common lumbar spine diagnoses were disk herniation (36.6%) and stenosis (34.8%), and most common cervical spine diagnoses were stenosis (50.0%) and disk herniation (23.2%). Back pain was reported by 93.8% of lumbar patients and leg pain by 83.0%. Neck pain was reported by 96.4% of cervical patients and arm pain by 69.6%. Median SF-12 physical component scores were more than two standard deviations below the US average. Ninety percent of patients had at least moderate physical disability. Sixty-four percent met criteria for depressive symptoms. Visual analog pain score was the strongest predictor of SF-12 physical (β = −1.32, P < 0.001) and mental (β = −1.63, P < 0.001) HRQOL and was the prime determinant of depressive symptoms (β = 1.52, P < 0.001) and disability index score (β = 4.39, P < 0.0001). Charlson Comorbidity Score and smoking status had no significant impact on HRQOL or disability scores. Age was negatively correlated with depressive symptoms and positively correlated with SF-12 mental component scores.

Conclusions

Spinal disorders have a severe impact on both physical and emotional HRQOL of Veterans and are associated with severe disability and an unusually high prevalence of depressive symptoms. Therapeutic interventions should be targeted to reduce pain, which is a prime determinant of HRQOL, disability, and depressive symptoms. Given high prevalence of multiple risk factors for poor outcomes, studies of spine surgery outcomes in Veterans are needed.
Literatuur
1.
go back to reference Singh, J. A., & Strand, V. (2009). Health care utilization in patients with spondyloarthropathies. Rheumatology (Oxford), 48(3), 272–276.CrossRef Singh, J. A., & Strand, V. (2009). Health care utilization in patients with spondyloarthropathies. Rheumatology (Oxford), 48(3), 272–276.CrossRef
2.
go back to reference Singh, J. A., & Strand, V. (2009). Spondyloarthritis is associated with poor function and physical health-related quality of life. Journal of Rheumatology, 36(5), 1012–1020.PubMedCrossRef Singh, J. A., & Strand, V. (2009). Spondyloarthritis is associated with poor function and physical health-related quality of life. Journal of Rheumatology, 36(5), 1012–1020.PubMedCrossRef
3.
go back to reference Butchart, A., Kerr, E. A., Heisler, M., Piette, J. D., & Krein, S. L. (2009). Experience and management of chronic pain among patients with other complex chronic conditions. Clinical Journal of Pain, 25(4), 293–298.PubMedCrossRef Butchart, A., Kerr, E. A., Heisler, M., Piette, J. D., & Krein, S. L. (2009). Experience and management of chronic pain among patients with other complex chronic conditions. Clinical Journal of Pain, 25(4), 293–298.PubMedCrossRef
4.
go back to reference Sinnott, P., & Wagner, T. H. (2009). Low back pain in VA users. Archives of Internal Medicine, 169(14), 1338–1339. author reply 1339.PubMedCrossRef Sinnott, P., & Wagner, T. H. (2009). Low back pain in VA users. Archives of Internal Medicine, 169(14), 1338–1339. author reply 1339.PubMedCrossRef
5.
go back to reference Gironda, R. J., Clark, M. E., Massengale, J. P., & Walker, R. L. (2006). Pain among veterans of operations enduring freedom and Iraqi freedom. Pain Med, 7(4), 339–343.PubMedCrossRef Gironda, R. J., Clark, M. E., Massengale, J. P., & Walker, R. L. (2006). Pain among veterans of operations enduring freedom and Iraqi freedom. Pain Med, 7(4), 339–343.PubMedCrossRef
6.
go back to reference Luo, J., Zhang, H. T., Jiang, X. D., Xue, S., & Ke, Y. Q. (2009). Combination of bone marrow stromal cell transplantation with mobilization by granulocyte-colony stimulating factor promotes functional recovery after spinal cord transection. Acta Neurochir (Wien), 151(11), 1483–1492.CrossRef Luo, J., Zhang, H. T., Jiang, X. D., Xue, S., & Ke, Y. Q. (2009). Combination of bone marrow stromal cell transplantation with mobilization by granulocyte-colony stimulating factor promotes functional recovery after spinal cord transection. Acta Neurochir (Wien), 151(11), 1483–1492.CrossRef
7.
go back to reference Fanuele, J. C., Birkmeyer, N. J., Abdu, W. A., Tosteson, T. D., & Weinstein, J. N. (2000). The impact of spinal problems on the health status of patients: Have we underestimated the effect? Spine, 25(12), 1509–1514.PubMedCrossRef Fanuele, J. C., Birkmeyer, N. J., Abdu, W. A., Tosteson, T. D., & Weinstein, J. N. (2000). The impact of spinal problems on the health status of patients: Have we underestimated the effect? Spine, 25(12), 1509–1514.PubMedCrossRef
8.
go back to reference Slover, J., Abdu, W. A., Hanscom, B., Lurie, J., & Weinstein, J. N. (2006). Can condition-specific health surveys be specific to spine disease? An analysis of the effect of comorbidities on baseline condition-specific and general health survey scores. Spine (Phila Pa 1976), 31(11), 1265–1271.CrossRef Slover, J., Abdu, W. A., Hanscom, B., Lurie, J., & Weinstein, J. N. (2006). Can condition-specific health surveys be specific to spine disease? An analysis of the effect of comorbidities on baseline condition-specific and general health survey scores. Spine (Phila Pa 1976), 31(11), 1265–1271.CrossRef
9.
go back to reference Saban, K. L., & Penckofer, S. M. (2007). Patient expectations of quality of life following lumbar spinal surgery. Journal of Neuroscience Nursing, 39(3), 180–189.PubMedCrossRef Saban, K. L., & Penckofer, S. M. (2007). Patient expectations of quality of life following lumbar spinal surgery. Journal of Neuroscience Nursing, 39(3), 180–189.PubMedCrossRef
10.
go back to reference Singh, A., Gnanalingham, K., Casey, A., & Crockard, A. (2006). Quality of life assessment using the Short Form-12 (SF-12) questionnaire in patients with cervical spondylotic myelopathy: Comparison with SF-36. Spine (Phila Pa 1976), 31(6), 639–643.CrossRef Singh, A., Gnanalingham, K., Casey, A., & Crockard, A. (2006). Quality of life assessment using the Short Form-12 (SF-12) questionnaire in patients with cervical spondylotic myelopathy: Comparison with SF-36. Spine (Phila Pa 1976), 31(6), 639–643.CrossRef
11.
go back to reference Slover, J., Abdu, W. A., Hanscom, B., & Weinstein, J. N. (2006). The impact of comorbidities on the change in short-form 36 and Oswestry scores following lumbar spine surgery. Spine (Phila Pa 1976), 31(17), 1974–1980.CrossRef Slover, J., Abdu, W. A., Hanscom, B., & Weinstein, J. N. (2006). The impact of comorbidities on the change in short-form 36 and Oswestry scores following lumbar spine surgery. Spine (Phila Pa 1976), 31(17), 1974–1980.CrossRef
12.
go back to reference Singh, J. A. (2009). Effect of comorbidity on quality of life of male veterans with prevalent primary total knee arthroplasty. Clinical Rheumatology, 28(9), 1083–1089.PubMedCrossRef Singh, J. A. (2009). Effect of comorbidity on quality of life of male veterans with prevalent primary total knee arthroplasty. Clinical Rheumatology, 28(9), 1083–1089.PubMedCrossRef
13.
go back to reference Singh, J. A., & Sloan, J. (2009). Higher comorbidity, poor functional status and higher health care utilization in veterans with prevalent total knee arthroplasty or total hip arthroplasty. Clinical Rheumatology, 28(9), 1025–1033.PubMedCrossRef Singh, J. A., & Sloan, J. (2009). Higher comorbidity, poor functional status and higher health care utilization in veterans with prevalent total knee arthroplasty or total hip arthroplasty. Clinical Rheumatology, 28(9), 1025–1033.PubMedCrossRef
14.
go back to reference Kazis, L. E., Ren, X. S., Lee, A., Skinner, K., Rogers, W., Clark, J., et al. (1999). Health status in VA patients: Results from the Veterans Health Study. American Journal of Medical Quality, 14(1), 28–38.PubMedCrossRef Kazis, L. E., Ren, X. S., Lee, A., Skinner, K., Rogers, W., Clark, J., et al. (1999). Health status in VA patients: Results from the Veterans Health Study. American Journal of Medical Quality, 14(1), 28–38.PubMedCrossRef
15.
go back to reference Charlson, M. E., Pompei, P., Ales, K. L., & MacKenzie, C. R. (1987). A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. J Chronic Dis, 40(5), 373–383.PubMedCrossRef Charlson, M. E., Pompei, P., Ales, K. L., & MacKenzie, C. R. (1987). A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. J Chronic Dis, 40(5), 373–383.PubMedCrossRef
16.
go back to reference Fairbank, J. C., Couper, J., Davies, J. B., & O’Brien, J. P. (1980). The Oswestry low back pain disability questionnaire. Physiotherapy, 66(8), 271–273.PubMed Fairbank, J. C., Couper, J., Davies, J. B., & O’Brien, J. P. (1980). The Oswestry low back pain disability questionnaire. Physiotherapy, 66(8), 271–273.PubMed
17.
go back to reference Vernon, H., & Mior, S. (1991). The neck disability index: A study of reliability and validity. Journal of Manipulative and Physiological Therapeutics, 14(7), 409–415.PubMed Vernon, H., & Mior, S. (1991). The neck disability index: A study of reliability and validity. Journal of Manipulative and Physiological Therapeutics, 14(7), 409–415.PubMed
18.
go back to reference Luo, X., Lynn George, M., Kakouras, I., Edwards, C. L., Pietrobon, R., Richardson, W., et al. (2003). Reliability, validity, and responsiveness of the short form 12-item survey (SF-12) in patients with back pain. Spine (Phila Pa 1976), 28(15), 1739–1745. Luo, X., Lynn George, M., Kakouras, I., Edwards, C. L., Pietrobon, R., Richardson, W., et al. (2003). Reliability, validity, and responsiveness of the short form 12-item survey (SF-12) in patients with back pain. Spine (Phila Pa 1976), 28(15), 1739–1745.
19.
go back to reference Walsh, T. L., Hanscom, B., Lurie, J. D., & Weinstein, J. N. (2003). Is a condition-specific instrument for patients with low back pain/leg symptoms really necessary? The responsiveness of the Oswestry disability index, MODEMS, and the SF-36. Spine (Phila Pa 1976), 28(6), 607–615. Walsh, T. L., Hanscom, B., Lurie, J. D., & Weinstein, J. N. (2003). Is a condition-specific instrument for patients with low back pain/leg symptoms really necessary? The responsiveness of the Oswestry disability index, MODEMS, and the SF-36. Spine (Phila Pa 1976), 28(6), 607–615.
20.
go back to reference Beck, A. T., Ward, C. H., Mendelson, M., Mock, J., & Erbaugh, J. (1961). An inventory for measuring depression. Archives of General Psychiatry, 4, 561–571.PubMedCrossRef Beck, A. T., Ward, C. H., Mendelson, M., Mock, J., & Erbaugh, J. (1961). An inventory for measuring depression. Archives of General Psychiatry, 4, 561–571.PubMedCrossRef
21.
go back to reference Beck, A. T., & Steer, R. A. (1984). Internal consistencies of the original and revised Beck depression inventory. Journal of Clinical Psychology, 40(6), 1365–1367.PubMedCrossRef Beck, A. T., & Steer, R. A. (1984). Internal consistencies of the original and revised Beck depression inventory. Journal of Clinical Psychology, 40(6), 1365–1367.PubMedCrossRef
22.
go back to reference Schotte, C. K., Maes, M., Cluydts, R., De Doncker, D., & Cosyns, P. (1997). Construct validity of the Beck depression inventory in a depressive population. Journal of Affective Disorders, 46(2), 115–125.PubMedCrossRef Schotte, C. K., Maes, M., Cluydts, R., De Doncker, D., & Cosyns, P. (1997). Construct validity of the Beck depression inventory in a depressive population. Journal of Affective Disorders, 46(2), 115–125.PubMedCrossRef
23.
go back to reference Lustman, P. J., Clouse, R. E., Griffith, L. S., Carney, R. M., & Freedland, K. E. (1997). Screening for depression in diabetes using the Beck depression inventory. Psychosomatic Medicine, 59(1), 24–31.PubMed Lustman, P. J., Clouse, R. E., Griffith, L. S., Carney, R. M., & Freedland, K. E. (1997). Screening for depression in diabetes using the Beck depression inventory. Psychosomatic Medicine, 59(1), 24–31.PubMed
24.
go back to reference Ware, J., Jr, Kosinski, M., & Keller, S. D. (1996). A 12-item short-form health survey: Construction of scales and preliminary tests of reliability and validity. Medical Care, 34(3), 220–233.PubMedCrossRef Ware, J., Jr, Kosinski, M., & Keller, S. D. (1996). A 12-item short-form health survey: Construction of scales and preliminary tests of reliability and validity. Medical Care, 34(3), 220–233.PubMedCrossRef
25.
go back to reference Venables, W. N., & Ripley, B. D. (2002). Modern applied statistics with S. New York: Springer.CrossRef Venables, W. N., & Ripley, B. D. (2002). Modern applied statistics with S. New York: Springer.CrossRef
26.
go back to reference Faraway, J. J. (2005). Linear models with R. New York: Chapman & Hall/CRC. Faraway, J. J. (2005). Linear models with R. New York: Chapman & Hall/CRC.
27.
go back to reference Gage, H., Hendricks, A., Zhang, S., & Kazis, L. (2003). The relative health related quality of life of veterans with Parkinson’s disease. Journal of Neurology, Neurosurgery and Psychiatry, 74(2), 163–169.CrossRef Gage, H., Hendricks, A., Zhang, S., & Kazis, L. (2003). The relative health related quality of life of veterans with Parkinson’s disease. Journal of Neurology, Neurosurgery and Psychiatry, 74(2), 163–169.CrossRef
28.
go back to reference Trief, P. M., Ploutz-Snyder, R., & Fredrickson, B. E. (2006). Emotional health predicts pain and function after fusion: A prospective multicenter study. Spine (Phila Pa 1976), 31(7), 823–830.CrossRef Trief, P. M., Ploutz-Snyder, R., & Fredrickson, B. E. (2006). Emotional health predicts pain and function after fusion: A prospective multicenter study. Spine (Phila Pa 1976), 31(7), 823–830.CrossRef
29.
go back to reference Trief, P. M., Grant, W., & Fredrickson, B. (2000). A prospective study of psychological predictors of lumbar surgery outcome. Spine (Phila Pa 1976), 25(20), 2616–2621.CrossRef Trief, P. M., Grant, W., & Fredrickson, B. (2000). A prospective study of psychological predictors of lumbar surgery outcome. Spine (Phila Pa 1976), 25(20), 2616–2621.CrossRef
30.
go back to reference Mannion, A. F., & Elfering, A. (2006). Predictors of surgical outcome and their assessment. European Spine Journal, 15(Suppl 1), S93–S108.PubMedCrossRef Mannion, A. F., & Elfering, A. (2006). Predictors of surgical outcome and their assessment. European Spine Journal, 15(Suppl 1), S93–S108.PubMedCrossRef
31.
go back to reference Sinikallio, S., Aalto, T., Airaksinen, O., Herno, A., Kroger, H., Savolainen, S., et al. (2006). Depression and associated factors in patients with lumbar spinal stenosis. Disability and Rehabilitation, 28(7), 415–422.PubMedCrossRef Sinikallio, S., Aalto, T., Airaksinen, O., Herno, A., Kroger, H., Savolainen, S., et al. (2006). Depression and associated factors in patients with lumbar spinal stenosis. Disability and Rehabilitation, 28(7), 415–422.PubMedCrossRef
32.
go back to reference Sinikallio, S., Aalto, T., Lehto, S. M., Airaksinen, O., Herno, A., Kroger, H., et al. (2010). Depressive symptoms predict postoperative disability among patients with lumbar spinal stenosis: A two-year prospective study comparing two age groups. Disability and Rehabilitation, 32(6), 462–468.PubMedCrossRef Sinikallio, S., Aalto, T., Lehto, S. M., Airaksinen, O., Herno, A., Kroger, H., et al. (2010). Depressive symptoms predict postoperative disability among patients with lumbar spinal stenosis: A two-year prospective study comparing two age groups. Disability and Rehabilitation, 32(6), 462–468.PubMedCrossRef
33.
go back to reference Sinikallio, S., Aalto, T., Airaksinen, O., Herno, A., Kroger, H., Savolainen, S., et al. (2007). Depression is associated with poorer outcome of lumbar spinal stenosis surgery. European Spine Journal, 16(7), 905–912.PubMedCrossRef Sinikallio, S., Aalto, T., Airaksinen, O., Herno, A., Kroger, H., Savolainen, S., et al. (2007). Depression is associated with poorer outcome of lumbar spinal stenosis surgery. European Spine Journal, 16(7), 905–912.PubMedCrossRef
34.
go back to reference Callahan, C. M., Hui, S. L., Nienaber, N. A., Musick, B. S., & Tierney, W. M. (1994). Longitudinal study of depression and health services use among elderly primary care patients. Journal of the American Geriatrics Society, 42(8), 833–838.PubMed Callahan, C. M., Hui, S. L., Nienaber, N. A., Musick, B. S., & Tierney, W. M. (1994). Longitudinal study of depression and health services use among elderly primary care patients. Journal of the American Geriatrics Society, 42(8), 833–838.PubMed
35.
go back to reference Kessler, R. C., Berglund, P., Demler, O., Jin, R., Koretz, D., Merikangas, K. R., et al. (2003). National comorbidity survey replication: The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA, 289(23), 3095–3105.PubMedCrossRef Kessler, R. C., Berglund, P., Demler, O., Jin, R., Koretz, D., Merikangas, K. R., et al. (2003). National comorbidity survey replication: The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA, 289(23), 3095–3105.PubMedCrossRef
36.
go back to reference Hankin, C. S., Spiro, A., I. I. I., Miller, D. R., & Kazis, L. (1999). Mental disorders and mental health treatment among U.S. Department of Veterans Affairs outpatients: The Veterans health study. American Journal of Psychiatry, 156(12), 1924–1930.PubMed Hankin, C. S., Spiro, A., I. I. I., Miller, D. R., & Kazis, L. (1999). Mental disorders and mental health treatment among U.S. Department of Veterans Affairs outpatients: The Veterans health study. American Journal of Psychiatry, 156(12), 1924–1930.PubMed
37.
go back to reference Kazis, L. E., Miller, D. R., Clark, J., Skinner, K., Lee, A., Rogers, W., et al. (1998). Health-related quality of life in patients served by the Department of Veterans Affairs: Results from the Veterans health study. Archives of Internal Medicine, 158(6), 626–632.PubMedCrossRef Kazis, L. E., Miller, D. R., Clark, J., Skinner, K., Lee, A., Rogers, W., et al. (1998). Health-related quality of life in patients served by the Department of Veterans Affairs: Results from the Veterans health study. Archives of Internal Medicine, 158(6), 626–632.PubMedCrossRef
38.
go back to reference Ren, X. S., Kazis, L. E., Lee, A., & Rogers, W. H. (2005). The role of generic and disease-specific measures of physical and role functioning in assessing patient outcomes: a longitudinal study. J Ambul Care Manage, 28(2), 157–166.PubMed Ren, X. S., Kazis, L. E., Lee, A., & Rogers, W. H. (2005). The role of generic and disease-specific measures of physical and role functioning in assessing patient outcomes: a longitudinal study. J Ambul Care Manage, 28(2), 157–166.PubMed
39.
go back to reference Fries, J. F., Krishnan, E., Rose, M., Lingala, B., & Bruce, B. (2011). Improved responsiveness and reduced sample size requirements of PROMIS physical function scales with item response theory. Arthritis Res Ther, 13(5), R147.PubMedCrossRef Fries, J. F., Krishnan, E., Rose, M., Lingala, B., & Bruce, B. (2011). Improved responsiveness and reduced sample size requirements of PROMIS physical function scales with item response theory. Arthritis Res Ther, 13(5), R147.PubMedCrossRef
40.
go back to reference Fries, J. F., Cella, D., Rose, M., Krishnan, E., & Bruce, B. (2009). Progress in assessing physical function in arthritis: PROMIS short forms and computerized adaptive testing. Journal of Rheumatology, 36(9), 2061–2066.PubMedCrossRef Fries, J. F., Cella, D., Rose, M., Krishnan, E., & Bruce, B. (2009). Progress in assessing physical function in arthritis: PROMIS short forms and computerized adaptive testing. Journal of Rheumatology, 36(9), 2061–2066.PubMedCrossRef
41.
go back to reference Mannion, A. F., Elfering, A., Staerkle, R., Junge, A., Grob, D., Dvorak, J., et al. (2007). Predictors of multidimensional outcome after spinal surgery. European Spine Journal, 16(6), 777–786.PubMedCrossRef Mannion, A. F., Elfering, A., Staerkle, R., Junge, A., Grob, D., Dvorak, J., et al. (2007). Predictors of multidimensional outcome after spinal surgery. European Spine Journal, 16(6), 777–786.PubMedCrossRef
Metagegevens
Titel
Health-related quality-of-life status in Veterans with spinal disorders
Auteurs
Maxwell Boakye
Ryan Moore
Maiying Kong
Stephen L. Skirboll
Robert T. Arrigo
Publicatiedatum
01-02-2013
Uitgeverij
Springer Netherlands
Gepubliceerd in
Quality of Life Research / Uitgave 1/2013
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-012-0121-y

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