Skip to main content
Top
Gepubliceerd in:

22-11-2022

Health-related quality of life of Chinese AIDS patients: a multi-region study

Auteurs: Pei Wang, Jun-Yang Gao, Hui-Jun Zhou, Jing Wu, Ying Wang

Gepubliceerd in: Quality of Life Research | Uitgave 4/2023

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Objective

To assess the health-related quality of life (HRQOL) of Chinese AIDS patients in three regions (Shanghai, Zhejiang, and Henan) and to examine the relationship between region and the HRQOL.

Method

A cross-sectional study was conducted from 2017 to 2018. Multistage stratified sampling was employed to recruit 1,273 AIDS patients from local Centers for Disease Control and Prevention. Data were collected by means of face-to-face interview using a structured questionnaire including the SF-12 and various rating scales. The multivariate linear and logistic regression models were performed to analyze the relationship of region and a variety of factors with the HRQOL and health utility.

Results

The three most affected dimensions were mental health, general health, and vitality as 18.2%, 18.0%, and 16.4% of the patients reported problems respectively. The mean (SD) scores of physical component summary (PCS) and mental component summary (MCS), were 48.19 (8.02) and 46.74 (10.71) respectively. The mean (SD) health utility score was 0.75 (0.13) assessed by the SF-6D derived from the SF-12. Region, age, employment status, individual income, government assistance and stigma significantly affected the patients’ HRQOL (P < 0.01). BMI, opportunistic infection, treatment compliance and time of treatment were also found to be significant factors of the HRQOL.

Conclusion

This study comprehensively estimated the HRQOL and health utility for the AIDS population in China, their HRQOL was mainly deteriorated in psychological dimensions, and geographical area may be closely related. Hence, close attention needs to be paid on the regional differences in HRQOL and the psychological problems of the patients.
Bijlagen
Alleen toegankelijk voor geautoriseerde gebruikers
Literatuur
2.
go back to reference Liu, X. J., McGoogan, J. M., & Wu, Z. Y. (2021). Human immunodeficiency virus/acquired immunodeficiency syndrome prevalence, incidence, and mortality in China, 1990 to 2017: A secondary analysis of the Global Burden of Disease Study 2017 data. Chinese Medical Journal (Engl), 134(10), 1175–1180. https://doi.org/10.1097/cm9.0000000000001447CrossRef Liu, X. J., McGoogan, J. M., & Wu, Z. Y. (2021). Human immunodeficiency virus/acquired immunodeficiency syndrome prevalence, incidence, and mortality in China, 1990 to 2017: A secondary analysis of the Global Burden of Disease Study 2017 data. Chinese Medical Journal (Engl), 134(10), 1175–1180. https://​doi.​org/​10.​1097/​cm9.​0000000000001447​CrossRef
8.
go back to reference Dong, X., Peng, L., Zhang, S., Li, Y., Cai, W., Wang, H., Ye, Y., Yang, J., & Wang, S. (2014). Quality of life and related factors among people living with HIV/AIDS in Guangdong province. Zhonghua Liu Xing Bing Xue Za Zhi, 35(1), 40–44.PubMed Dong, X., Peng, L., Zhang, S., Li, Y., Cai, W., Wang, H., Ye, Y., Yang, J., & Wang, S. (2014). Quality of life and related factors among people living with HIV/AIDS in Guangdong province. Zhonghua Liu Xing Bing Xue Za Zhi, 35(1), 40–44.PubMed
10.
go back to reference Wang, X., Guo, G., Liang, X., Zhou, L., Zheng, J., Li, S., Luo, H., Yang, Y., Yang, L., Tan, T., Yu, J., & Lu, L. (2018). Health utility of pregnant women living with HIV/AIDS: Prevention of mother-to-child transmission of HIV (PMTCT) programs in Yunnan Province: A cross-sectional study. Value in health regional issues, 15, 27–33. https://doi.org/10.1016/j.vhri.2017.05.004CrossRefPubMed Wang, X., Guo, G., Liang, X., Zhou, L., Zheng, J., Li, S., Luo, H., Yang, Y., Yang, L., Tan, T., Yu, J., & Lu, L. (2018). Health utility of pregnant women living with HIV/AIDS: Prevention of mother-to-child transmission of HIV (PMTCT) programs in Yunnan Province: A cross-sectional study. Value in health regional issues, 15, 27–33. https://​doi.​org/​10.​1016/​j.​vhri.​2017.​05.​004CrossRefPubMed
12.
16.
go back to reference Wu, J., Xie, S., He, X., Chen, G., Bai, G., Feng, D., Hu, M., Jiang, J., Wang, X., Wu, H., Wu, Q., & Brazier, J. E. (2021). Valuation of SF-6Dv2 health states in china using time trade-off and discrete-choice experiment with a duration dimension. Pharmaco Economics, 39(5), 521–535. https://doi.org/10.1007/s40273-020-00997-1CrossRef Wu, J., Xie, S., He, X., Chen, G., Bai, G., Feng, D., Hu, M., Jiang, J., Wang, X., Wu, H., Wu, Q., & Brazier, J. E. (2021). Valuation of SF-6Dv2 health states in china using time trade-off and discrete-choice experiment with a duration dimension. Pharmaco Economics, 39(5), 521–535. https://​doi.​org/​10.​1007/​s40273-020-00997-1CrossRef
20.
go back to reference Jiao, F., Wong, C. K. H., Gangwani, R., Tan, K. C. B., Tang, S. C. W., & Lam, C. L. K. (2017). Health-related quality of life and health preference of Chinese patients with diabetes mellitus managed in primary care and secondary care setting: Decrements associated with individual complication and number of complications. Health and Quality of Life Outcomes, 15(1), 125. https://doi.org/10.1186/s12955-017-0699-4CrossRefPubMedPubMedCentral Jiao, F., Wong, C. K. H., Gangwani, R., Tan, K. C. B., Tang, S. C. W., & Lam, C. L. K. (2017). Health-related quality of life and health preference of Chinese patients with diabetes mellitus managed in primary care and secondary care setting: Decrements associated with individual complication and number of complications. Health and Quality of Life Outcomes, 15(1), 125. https://​doi.​org/​10.​1186/​s12955-017-0699-4CrossRefPubMedPubMedCentral
24.
go back to reference Shao, B., Song, B., Feng, S., Lin, Y., Du, J., Shao, H., Chi, Z., Yang, Y., & Wang, F. (2018). The relationship of social support, mental health, and health-related quality of life in human immunodeficiency virus-positive men who have sex with men: From the analysis of canonical correlation and structural equation model: A cross-sectional study. Medicine (Baltimore), 97(30), e11652. https://doi.org/10.1097/md.0000000000011652CrossRefPubMed Shao, B., Song, B., Feng, S., Lin, Y., Du, J., Shao, H., Chi, Z., Yang, Y., & Wang, F. (2018). The relationship of social support, mental health, and health-related quality of life in human immunodeficiency virus-positive men who have sex with men: From the analysis of canonical correlation and structural equation model: A cross-sectional study. Medicine (Baltimore), 97(30), e11652. https://​doi.​org/​10.​1097/​md.​0000000000011652​CrossRefPubMed
25.
go back to reference Wang, X., Luo, H., Yao, E., Tang, R., Dong, W., Liu, F., Liang, J., Li, H., Xiao, M., Zhang, Z., Niu, J., Song, L., Fu, L., Li, X., Qian, S., Guo, Q., & Song, Z. (2021). The role of personality, social economic and prevention strategy effects on health-related quality of life among people living with HIV/AIDS. Infectious Diseases of Poverty, 10(1), 104. https://doi.org/10.1186/s40249-021-00890-9CrossRefPubMedPubMedCentral Wang, X., Luo, H., Yao, E., Tang, R., Dong, W., Liu, F., Liang, J., Li, H., Xiao, M., Zhang, Z., Niu, J., Song, L., Fu, L., Li, X., Qian, S., Guo, Q., & Song, Z. (2021). The role of personality, social economic and prevention strategy effects on health-related quality of life among people living with HIV/AIDS. Infectious Diseases of Poverty, 10(1), 104. https://​doi.​org/​10.​1186/​s40249-021-00890-9CrossRefPubMedPubMedCentral
29.
go back to reference Taylor, B. S., Tieu, H. V., Jones, J., & Wilkin, T. J. (2019). CROI 2019: Advances in antiretroviral therapy. Topics in Antiviral Medicine, 27(1), 50–68.PubMedPubMedCentral Taylor, B. S., Tieu, H. V., Jones, J., & Wilkin, T. J. (2019). CROI 2019: Advances in antiretroviral therapy. Topics in Antiviral Medicine, 27(1), 50–68.PubMedPubMedCentral
Metagegevens
Titel
Health-related quality of life of Chinese AIDS patients: a multi-region study
Auteurs
Pei Wang
Jun-Yang Gao
Hui-Jun Zhou
Jing Wu
Ying Wang
Publicatiedatum
22-11-2022
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 4/2023
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-022-03299-5