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Gepubliceerd in: Quality of Life Research 3/2022

03-08-2021

Health-related quality of life deviations from population norms in patients with lumbar radiculopathy: associations with pain, pain cognitions, and endogenous nociceptive modulation

Auteurs: Wouter Van Bogaert, Koen Putman, Iris Coppieters, Lisa Goudman, Jo Nijs, Maarten Moens, Ronald Buyl, Kelly Ickmans, Eva Huysmans

Gepubliceerd in: Quality of Life Research | Uitgave 3/2022

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Abstract

Purpose

The primary goal of this study was to compare the health-related quality of life (HRQoL) of people with lumbar radiculopathy to age- and sex-adjusted population norms. Additionally, it aimed to explore the associations between the HRQoL difference scores and measures related to pain cognitions, pain intensity, and endogenous nociceptive modulation.

Methods

Using answers from the Short Form 36-item Health Survey and UK population norms, SF-6D difference scores were calculated. A one-sample t test was used to assess the SF-6D difference scores. Univariate and multivariate regression analyses were used to assess the associations between SF-6D difference scores and pain intensity [Visual Analogue Scale (VAS) for back and leg pain], pain cognitions [Pain Catastrophizing Scale (PCS), Tampa Scale for Kinesiophobia (TSK), Pain Vigilance and Awareness Questionnaire (PVAQ)], and correlates for endogenous nociceptive modulation using quantitative sensory testing.

Results

One hundred and twenty people with lumbar radiculopathy scheduled for surgery were included in this study. The mean SF-6D difference score of − 0.26 [SD = 0.09] was found to be significantly less than 0 [95%CI: − 0.27 to − 0.24]. Univariate analyses showed a significant influence from PCS, TSK, and PVAQ on the SF-6D difference scores. The final multivariate regression model included PCS and PVAQ, with only PCS maintaining a statistically significant regression coefficient [b = − 0.002; 95% CI: − 0.004 to − 0.001].

Conclusion

People diagnosed with lumbar radiculopathy report significantly lower HRQoL scores when compared with age- and sex-adjusted UK norm values. Even though all examined pain cognitions were found to have a significant association, pain catastrophizing showed the most significant relation to the SF-6D difference scores.

Clinical trial registration

ClinicalTrials.gov Identifier No. NCT02630732. Date of registration: November 25, 2015.
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Metagegevens
Titel
Health-related quality of life deviations from population norms in patients with lumbar radiculopathy: associations with pain, pain cognitions, and endogenous nociceptive modulation
Auteurs
Wouter Van Bogaert
Koen Putman
Iris Coppieters
Lisa Goudman
Jo Nijs
Maarten Moens
Ronald Buyl
Kelly Ickmans
Eva Huysmans
Publicatiedatum
03-08-2021
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 3/2022
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-021-02964-5

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