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Gepubliceerd in: Quality of Life Research 12/2018

02-08-2018

Health-related quality of life among pulmonary tuberculosis patients in Pakistan

Auteurs: Saniya Saleem, Amyn A. Malik, Asma Ghulam, Junaid Ahmed, Hamidah Hussain

Gepubliceerd in: Quality of Life Research | Uitgave 12/2018

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Abstract

Purpose

Health-related quality of life (HRQoL) of pulmonary TB patients has not been assessed in Pakistan. We assessed self-reported HRQoL of pulmonary TB patients in Karachi, Pakistan utilizing the EQ-5D and EQ-VAS prior to, during, and after completion of TB treatment.

Methods

We enrolled 226 pulmonary TB patients in a longitudinal cohort study. Health-utility scores were estimated by the EQ-5D five dimensions and the EQ-Visual Analogue Scale (VAS) at baseline (month 0) and each monthly follow-up visit until treatment completion at month 6. Repeated-measures ANOVA was used to investigate effect of time into treatment on EQ-5D and EQ-VAS scores.

Results

EQ-5D health utility and EQ-VAS scores increase with treatment progression. For the enrolled TB patients, the mean EQ-5D utility scores more than doubled from 0.43 to 0.88, p < .001, effect size η2 = 0.40 from treatment initiation to treatment completion.

Conclusion

Perceived HRQoL of TB patients improves with treatment progression. This can inform targeted treatment plans as well as TB policy and funding for high-burden countries.
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Metagegevens
Titel
Health-related quality of life among pulmonary tuberculosis patients in Pakistan
Auteurs
Saniya Saleem
Amyn A. Malik
Asma Ghulam
Junaid Ahmed
Hamidah Hussain
Publicatiedatum
02-08-2018
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 12/2018
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-018-1954-9

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