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15-07-2020 | Uitgave 11/2020 Open Access

Quality of Life Research 11/2020

Health-related quality of life after traumatic brain injury: deriving value sets for the QOLIBRI-OS for Italy, The Netherlands and The United Kingdom

Tijdschrift:
Quality of Life Research > Uitgave 11/2020
Auteurs:
Daphne C. Voormolen, Suzanne Polinder, Nicole von Steinbuechel, Yan Feng, Lindsay Wilson, Mark Oppe, Juanita A. Haagsma, the CENTER-TBI participants and investigators
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Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s11136-020-02583-6) contains supplementary material, which is available to authorized users.
The members of the CENTER-TBI Participants and Investigators has been included in ‘Acknowledgements’ section.

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Abstract

Purpose

The Quality of Life after Brain Injury overall scale (QOLIBRI-OS) measures health-related quality of life (HRQoL) after traumatic brain injury (TBI). The aim of this study was to derive value sets for the QOLIBRI-OS in three European countries, which will allow calculation of utility scores for TBI health states.

Methods

A QOLIBRI-OS value set was derived by using discrete choice experiments (DCEs) and visual analogue scales (VAS) in general population samples from the Netherlands, United Kingdom and Italy. A three-stage procedure was used: (1) A selection of health states, covering the entire spectrum of severity, was defined; (2) General population samples performed the health state valuation task using a web-based survey with three VAS questions and an at random selection of sixteen DCEs; (3) DCEs were analysed using a conditional logistic regression and were then anchored on the VAS data. Utility scores for QOLIBRI-OS health states were generated resulting in estimates for all potential health states.

Results

The questionnaire was completed by 13,623 respondents. The biggest weight increase for all attributes is seen from “slightly” to “not at all satisfied”, resulting in the largest impact on HRQoL. “Not at all satisfied with how brain is working” should receive the greatest weight in utility calculations in all three countries.

Conclusion

By transforming the QOLIBRI-OS into utility scores, we enabled the application in economic evaluations and in summary measures of population health, which may be used to inform decision-makers on the best interventions and strategies for TBI patients.

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