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Gepubliceerd in: Quality of Life Research 10/2021

01-05-2021

Health-related quality of life after first-ever acute ischemic stroke: associations with cardiovascular health metrics

Auteurs: Rui She, Zhongrui Yan, Yanlei Hao, Zuoji Zhang, Yifeng Du, Yajun Liang, Davide L. Vetrano, Joost Dekker, Bo Bai, Joseph T. F. Lau, Chengxuan Qiu

Gepubliceerd in: Quality of Life Research | Uitgave 10/2021

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Abstract

Purpose

To investigate the associations between cardiovascular health (CVH) metrics and health-related quality of life (HRQL) among patients with ischemic stroke in China, and further explore the role of physical and cognitive function in their associations.

Methods

This hospital-based study included 1714 patients with first-ever acute ischemic stroke (age ≥ 40 years; 36.7% women) who were admitted to two university hospitals in Shandong, China. We collected information on seven CVH metrics (smoking, body mass index, diet, physical activity, blood pressure, total cholesterol, and fasting blood glucose) through interviews, clinical examinations, and laboratory tests. EQ-5D-3L was used to assess HRQL. Cognitive and physical functioning was assessed by the Montreal Cognitive Assessment test and Barthel index, respectively. Data were analyzed using the general linear regression models.

Results

The average score (SD) was 0.746 (0.23) for HRQL index and 72.7 (15.8) for self-rated health. Optimal levels of four individual CVH metric components (diet, physical activity, blood pressure, and blood glucose) and a higher composite CVH score were significantly associated with a greater HRQL index and better self-rated health (p < 0.05 for all). Physical dependence and cognitive impairment were associated with a lower HRQL index and poorer self-rated health status (p < 0.001). Furthermore, the relationships between CVH metrics and HRQL index varied by functional status, such that their associations were statistically significant only among people who had physical dependence or cognitive impairment.

Conclusion

Achieving a better cardiovascular health profile is associated with better quality of life among ischemic stroke survivors, primarily in those with physical or cognitive impairment.
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Metagegevens
Titel
Health-related quality of life after first-ever acute ischemic stroke: associations with cardiovascular health metrics
Auteurs
Rui She
Zhongrui Yan
Yanlei Hao
Zuoji Zhang
Yifeng Du
Yajun Liang
Davide L. Vetrano
Joost Dekker
Bo Bai
Joseph T. F. Lau
Chengxuan Qiu
Publicatiedatum
01-05-2021
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 10/2021
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-021-02853-x

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