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01-08-2000 | Artikelen

Harttransplantatie bij kinderen, adolescenten en patiënten met congenitale hartvitia

Auteurs: L. Mertens, B. Eyskens, M. Gewillig

Gepubliceerd in: Tijdschrift voor Kindergeneeskunde | Uitgave 4/2000

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Samenvatting

De laatste jaren zijn er belangrijke ontwikkelingen geweest op het gebied van de pediatrische ruilhartoperaties. De vijfjaarsoverleving schommelt in de verschillende centra tussen 50 en 70%. Nieuwe immunosuppressieschema's, betere rejectiemonitoring en infectiepreventie hebben deze gunstige overlevingscijfers mogelijk gemaakt. Deze gunstige resultaten hebben gezorgd voor verdere uitbreiding van de transplantatie-indicaties. Meer kinderen met congenitale hartafwijkingen komen op de transplantatiewachtlijst terecht. Ook neonatale transplantaties worden in een aantal centra uitgevoerd, met vergelijkbare resultaten. De lange termijnoverleving is momenteel nog onduidelijk. De belangrijkste rem op de ruimere indicatiestelling is het tekort aan donorharten, waarvoor op termijn enkel de ontwikkeling van genetisch gemanipuleerde dierenharten potentieel een oplossing kan bieden.
Literatuur
go back to reference Barnard CN. A human cardiac transplant. S Afr Med J 1967;41:1271-74.PubMed Barnard CN. A human cardiac transplant. S Afr Med J 1967;41:1271-74.PubMed
go back to reference Caves PK, Billingham ME, Stinson EB, et al. Serial transvenous biopsy of the transplanted human heart: improved management of acute rejection episodes. Lancet 1974;1:821-6.CrossRefPubMed Caves PK, Billingham ME, Stinson EB, et al. Serial transvenous biopsy of the transplanted human heart: improved management of acute rejection episodes. Lancet 1974;1:821-6.CrossRefPubMed
go back to reference Borel JF. Immunosuppressieve properties of cyclosporin A (CyA). Transplant Proc 1980;12:233.PubMed Borel JF. Immunosuppressieve properties of cyclosporin A (CyA). Transplant Proc 1980;12:233.PubMed
go back to reference Hosenpud JD, Norvick RJ, Breen TJ, et al. The registry of the International Society for Heart and Lung Transplantation: twelfth official report. J Heart Lung Transplant 1995;114:805-15. Hosenpud JD, Norvick RJ, Breen TJ, et al. The registry of the International Society for Heart and Lung Transplantation: twelfth official report. J Heart Lung Transplant 1995;114:805-15.
go back to reference Bailey LL, Nehlesen-Canarella SL, Doroshow RW, et al . Cardiac allotransplantation in newborns as therapy for hypoplastic left heart syndrome. N Engl J Med 1986;315:949-51.PubMed Bailey LL, Nehlesen-Canarella SL, Doroshow RW, et al . Cardiac allotransplantation in newborns as therapy for hypoplastic left heart syndrome. N Engl J Med 1986;315:949-51.PubMed
go back to reference Shaddy RE, Naftel DC, Kirklin JK, et al. Outcome of cardiac transplantation in children. Survival in a contemporary multi-institutional experience. Circulation 1996;94 (suppl II), II-69-73. Shaddy RE, Naftel DC, Kirklin JK, et al. Outcome of cardiac transplantation in children. Survival in a contemporary multi-institutional experience. Circulation 1996;94 (suppl II), II-69-73.
go back to reference Miller W, Kaye M, Baum D. Pediatric heart, heart-lung and lund transplantation: the world experience from 1984 to 1993. Prog Pediatr Cardiol 1993;2:4-8.CrossRef Miller W, Kaye M, Baum D. Pediatric heart, heart-lung and lund transplantation: the world experience from 1984 to 1993. Prog Pediatr Cardiol 1993;2:4-8.CrossRef
go back to reference Chiavarelli M, Boucek MM, Nehlesen-Cannarella SL, et al. Neonatal cardiac transplantation. Intermediate-term results and incidence of rejection. Arch Surg 1992;127:1072-6.PubMed Chiavarelli M, Boucek MM, Nehlesen-Cannarella SL, et al. Neonatal cardiac transplantation. Intermediate-term results and incidence of rejection. Arch Surg 1992;127:1072-6.PubMed
go back to reference Sarris GE, Smith JA, Bernstein D, et al. Pediatric cardiac transplantation. The Stanford experience. Circulation 1994;90: II-51-5. Sarris GE, Smith JA, Bernstein D, et al. Pediatric cardiac transplantation. The Stanford experience. Circulation 1994;90: II-51-5.
go back to reference Hsu D, Addonizzio L, Smith C, et al. Cardiac transplantation in children with congenital heart disease. J Am Coll Cardiol 1995;26:743-9.CrossRefPubMed Hsu D, Addonizzio L, Smith C, et al. Cardiac transplantation in children with congenital heart disease. J Am Coll Cardiol 1995;26:743-9.CrossRefPubMed
go back to reference Gajarski RJ, Towbin JA, Bricker T, et al. Intermediate follow-up of pediatric heart transplant recipients with elevated pulmonary vascular resistance index. J Am Coll Cardiol 1994;23:1682-7.PubMedCrossRef Gajarski RJ, Towbin JA, Bricker T, et al. Intermediate follow-up of pediatric heart transplant recipients with elevated pulmonary vascular resistance index. J Am Coll Cardiol 1994;23:1682-7.PubMedCrossRef
go back to reference Zales VR, Pahl E, Backer CL, et al. Pharmacologic reduction of pretransplantation pulmonary vascular resistance predicts outcome after pediatric heart transplantation. J Heart Lung Transplant 1993;12:965-73.PubMed Zales VR, Pahl E, Backer CL, et al. Pharmacologic reduction of pretransplantation pulmonary vascular resistance predicts outcome after pediatric heart transplantation. J Heart Lung Transplant 1993;12:965-73.PubMed
go back to reference Radley-Smith RC. Long-term results of pediatric heart transplantation. J Heart Lung Transplant 1992;11:s277-81.PubMed Radley-Smith RC. Long-term results of pediatric heart transplantation. J Heart Lung Transplant 1992;11:s277-81.PubMed
go back to reference Gajarski RJ, Smith EO, Denfield SW, et al. Long-term results of triple-drug-based immunosuppression in non-neonatal pediatric heart transplant recipients. Transplantation 1998;65:1470-6.CrossRefPubMed Gajarski RJ, Smith EO, Denfield SW, et al. Long-term results of triple-drug-based immunosuppression in non-neonatal pediatric heart transplant recipients. Transplantation 1998;65:1470-6.CrossRefPubMed
go back to reference Armitage JM, Fricker FJ, Nido P del, et al. The clinical trial of FK506 as primary and rescue immunosuppression in pediatric cardiac transplantation. Transplant Proc 1991;23:3058-60.PubMed Armitage JM, Fricker FJ, Nido P del, et al. The clinical trial of FK506 as primary and rescue immunosuppression in pediatric cardiac transplantation. Transplant Proc 1991;23:3058-60.PubMed
go back to reference Dodd D, Brady L, Carden K, et al. Pattern of echocardiographic abnormalities with acute cardiac allograft rejection in adults: correlation with endomyocardial biopsy. J Heart Lung Transplant 1993;12:1009-19.PubMed Dodd D, Brady L, Carden K, et al. Pattern of echocardiographic abnormalities with acute cardiac allograft rejection in adults: correlation with endomyocardial biopsy. J Heart Lung Transplant 1993;12:1009-19.PubMed
go back to reference Boucek M, Mathis C, Kanakriyeh M, et al. Serial echocardiographic evaluation of cardiac graft rejection after infant heart transplantation. J Heart Lung Transplant 1993;12:824-31.PubMed Boucek M, Mathis C, Kanakriyeh M, et al. Serial echocardiographic evaluation of cardiac graft rejection after infant heart transplantation. J Heart Lung Transplant 1993;12:824-31.PubMed
go back to reference Addonizio L, Hsu DT, Douglas JF, et al. Decreasing incidence of coronary disease in pediatric cardiac transplant recipients using increased immunosuppression. Circulation 1993;88:224-9. Addonizio L, Hsu DT, Douglas JF, et al. Decreasing incidence of coronary disease in pediatric cardiac transplant recipients using increased immunosuppression. Circulation 1993;88:224-9.
Metagegevens
Titel
Harttransplantatie bij kinderen, adolescenten en patiënten met congenitale hartvitia
Auteurs
L. Mertens
B. Eyskens
M. Gewillig
Publicatiedatum
01-08-2000
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Tijdschrift voor Kindergeneeskunde / Uitgave 4/2000
Print ISSN: 0376-7442
Elektronisch ISSN: 1875-6840
DOI
https://doi.org/10.1007/BF03061291