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28-10-2019 | Original Paper

Gluten-Free Diet in Children with Autism Spectrum Disorders: A Randomized, Controlled, Single-Blinded Trial

Auteurs: Anna Piwowarczyk, Andrea Horvath, Ewa Pisula, Rafał Kawa, Hania Szajewska

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 2/2020

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Abstract

To determine whether a gluten-free diet (GFD) compared with a gluten-containing diet (GD) influences functioning of children with autism spectrum disorders (ASD), we performed a randomized, controlled, single-blinded trial. Sixty-six children (36–69 months) with ASD, within the normal IQ (> 70) range, who had been on a GFD for at least 8 weeks before enrollment were eligible for inclusion. After an 8-week run-in period on a GFD, the GFD group continued this diet and the GD group consumed at least one normal meal containing gluten per day for 6 months. There were no differences between groups in autistic symptoms, maladaptive behaviors, or intellectual abilities after the intervention. A GFD compared with a GD did not affect functioning of children with ASD.
Trial registration ClinicalTrials.gov, number NCT02280746.
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Metagegevens
Titel
Gluten-Free Diet in Children with Autism Spectrum Disorders: A Randomized, Controlled, Single-Blinded Trial
Auteurs
Anna Piwowarczyk
Andrea Horvath
Ewa Pisula
Rafał Kawa
Hania Szajewska
Publicatiedatum
28-10-2019
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 2/2020
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-019-04266-9

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