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2020 | OriginalPaper | Hoofdstuk

15. Geriatrische oncologie

Auteurs : Prof. dr. J. E. A. Portielje, Dr. N. A. de Glas, Dr. F. van den Bos

Gepubliceerd in: Leerboek oncologie

Uitgeverij: Bohn Stafleu van Loghum

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Samenvatting

Kanker is een ziekte die vooral voorkomt op hogere leeftijd en het aantal ouderen met kanker zal door de vergrijzing alleen maar toenemen de komende jaren. Bij oudere patiënten doet kanker zich vaak voor in de context van andere verouderingskenmerken, zoals comorbiditeit, verminderd fysiek en cognitief functioneren en krimpen van het sociale netwerk. Deze factoren maken dat er grote verschillen zijn tussen patiënten, en dit moet meegenomen worden in de keuze voor oncologische behandelingen. Daarom wordt in dit hoofdstuk ingegaan op de behandeling van kanker in de context van fysiologische veroudering.
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Literatuur
go back to reference Broekhuizen K, Pothof A, De Craen AJ, Mooijaart SP. Characteristics of randomized controlled trials designed for elderly: a systematic review. PLoS ONE. 2015;10(5):e0126709.CrossRef Broekhuizen K, Pothof A, De Craen AJ, Mooijaart SP. Characteristics of randomized controlled trials designed for elderly: a systematic review. PLoS ONE. 2015;10(5):e0126709.CrossRef
go back to reference Corre R, Greillier L, Le CH, et al. Use of a comprehensive geriatric assessment for the management of elderly patients with advanced non-small-cell lung cancer: the phase III randomized ESOGIA-GFPC-GECP 08-02 study. J Clin Oncol. 2016;34:1476–83.CrossRef Corre R, Greillier L, Le CH, et al. Use of a comprehensive geriatric assessment for the management of elderly patients with advanced non-small-cell lung cancer: the phase III randomized ESOGIA-GFPC-GECP 08-02 study. J Clin Oncol. 2016;34:1476–83.CrossRef
go back to reference Dekker JW, Van den Broek CB, Bastiaannet E, Van de Geest LG, Tollenaar RA, Liefers GJ. Importance of the first postoperative year in the prognosis of elderly colorectal cancer patients. Ann Surg Oncol. 2011;18(6):1533–9.CrossRef Dekker JW, Van den Broek CB, Bastiaannet E, Van de Geest LG, Tollenaar RA, Liefers GJ. Importance of the first postoperative year in the prognosis of elderly colorectal cancer patients. Ann Surg Oncol. 2011;18(6):1533–9.CrossRef
go back to reference De Glas NA, Kiderlen M, Bastiaannet E, De Craen AJ, Van de Water W, Van de Velde CJ, et al. Postoperative complications and survival of elderly breast cancer patients: a FOCUS study analysis. Breast Cancer Res Treat. 2013;138(2):561–9. De Glas NA, Kiderlen M, Bastiaannet E, De Craen AJ, Van de Water W, Van de Velde CJ, et al. Postoperative complications and survival of elderly breast cancer patients: a FOCUS study analysis. Breast Cancer Res Treat. 2013;138(2):561–9.
go back to reference Extermann M, Boler I, Reich RR, Lyman GH, Brown RH, DeFelice J, et al. Predicting the risk of chemotherapy toxicity in older patients: the Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score. Cancer. 2012;118(13):3377–86.CrossRef Extermann M, Boler I, Reich RR, Lyman GH, Brown RH, DeFelice J, et al. Predicting the risk of chemotherapy toxicity in older patients: the Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score. Cancer. 2012;118(13):3377–86.CrossRef
go back to reference Ferrucci L, Guralnik JM, Cavazzini C, et al. The frailty syndrome: a critical issue in geriatric oncology. Crit Rev Oncol Hematol. 2003;46:127–37.CrossRef Ferrucci L, Guralnik JM, Cavazzini C, et al. The frailty syndrome: a critical issue in geriatric oncology. Crit Rev Oncol Hematol. 2003;46:127–37.CrossRef
go back to reference Fried, et al. Arch Intern Med. 2011 Nov 14;171(20):1854–6. Fried, et al. Arch Intern Med. 2011 Nov 14;171(20):1854–6.
go back to reference Hamaker ME, Schiphorst AH, Ten Bokkel HD, Schaar C, Van Munster BC. The effect of a geriatric evaluation on treatment decisions for older cancer patients. A systematic review. Acta Oncol. 2014;53:289–96.CrossRef Hamaker ME, Schiphorst AH, Ten Bokkel HD, Schaar C, Van Munster BC. The effect of a geriatric evaluation on treatment decisions for older cancer patients. A systematic review. Acta Oncol. 2014;53:289–96.CrossRef
go back to reference Hamaker ME, Te Molder M, Thielen N, Van Munster BC, Schiphorst AH, Van Huis LH. The effect of a geriatric evaluation on treatment decisions and outcome for older cancer patients. A systematic review. J Geriatr Oncol. 2018;9(5):430–40.CrossRef Hamaker ME, Te Molder M, Thielen N, Van Munster BC, Schiphorst AH, Van Huis LH. The effect of a geriatric evaluation on treatment decisions and outcome for older cancer patients. A systematic review. J Geriatr Oncol. 2018;9(5):430–40.CrossRef
go back to reference Hurria A, Mohile S, Gajra A, Klepin H, Muss H, Chapman A, et al. Validation of a prediction tool for chemotherapy toxicity in older adults with cancer. J Clin Oncol. 2016;34(20):2366–71.CrossRef Hurria A, Mohile S, Gajra A, Klepin H, Muss H, Chapman A, et al. Validation of a prediction tool for chemotherapy toxicity in older adults with cancer. J Clin Oncol. 2016;34(20):2366–71.CrossRef
go back to reference IKNL-rapport Kankerzorg in Beeld – de Oudere patiënt, 2016. IKNL-rapport Kankerzorg in Beeld – de Oudere patiënt, 2016.
go back to reference Kunkler IH, et al. Review of current best practice and priorities for research in radiation oncology for elderly patients with cancer: the International Society of Geriatric Oncology (SIOG) task force. Ann Oncol. 2014;25:2134–46.CrossRef Kunkler IH, et al. Review of current best practice and priorities for research in radiation oncology for elderly patients with cancer: the International Society of Geriatric Oncology (SIOG) task force. Ann Oncol. 2014;25:2134–46.CrossRef
go back to reference Mohile SG, Dale W, Somerfield MR, Schonberg MA, Boyd CM, Burhenn PS, et al. Practical assessment and management of vulnerabilities in older patients receiving chemotherapy: ASCO guideline for geriatric oncology. J Clin Oncol. 2018 Aug 1;36(22):2326–47. Mohile SG, Dale W, Somerfield MR, Schonberg MA, Boyd CM, Burhenn PS, et al. Practical assessment and management of vulnerabilities in older patients receiving chemotherapy: ASCO guideline for geriatric oncology. J Clin Oncol. 2018 Aug 1;36(22):2326–47.
go back to reference Rao AV, Hsieh F, Feussner JR, Cohen HJ. Geriatric evaluation and management units in the care of the frail elderly cancer patient. J Gerontol A Biol Sci Med Sci. 2005;60(6):798–803.CrossRef Rao AV, Hsieh F, Feussner JR, Cohen HJ. Geriatric evaluation and management units in the care of the frail elderly cancer patient. J Gerontol A Biol Sci Med Sci. 2005;60(6):798–803.CrossRef
go back to reference Van Walree IC, Scheepers E, Van Huis-Tanja LH, Emmelot-Vonk MH, Bellera C, Soubeyran P, Hamaker ME. A systematic review on the association of the G8 with geriatric assessment, prognosis and course of treatment in older patients with cancer. J Geriatr Oncol. 2019;10(6):847–58.CrossRef Van Walree IC, Scheepers E, Van Huis-Tanja LH, Emmelot-Vonk MH, Bellera C, Soubeyran P, Hamaker ME. A systematic review on the association of the G8 with geriatric assessment, prognosis and course of treatment in older patients with cancer. J Geriatr Oncol. 2019;10(6):847–58.CrossRef
go back to reference Van de Water W, Bastiaannet E, Van de Velde CJ, Liefers GJ. Inclusion and analysis of older adults in RCTs. J Gen Intern Med. 2011;26(8):831.CrossRef Van de Water W, Bastiaannet E, Van de Velde CJ, Liefers GJ. Inclusion and analysis of older adults in RCTs. J Gen Intern Med. 2011;26(8):831.CrossRef
go back to reference Vandenbroucke JP. When are observational studies as credible as randomised trials? The Lancet. 2004;363(9422):1728–31.CrossRef Vandenbroucke JP. When are observational studies as credible as randomised trials? The Lancet. 2004;363(9422):1728–31.CrossRef
go back to reference Wildiers H, Mauer M, Pallis A, Hurria A, Mohile SG, Luciani A, et al. End points and trial design in geriatric oncology research: a joint European organisation for research and treatment of cancer; alliance for clinical trials in oncology – international society of geriatric oncology position article. J Clin Oncol. 2013;31(29):3711–8.CrossRef Wildiers H, Mauer M, Pallis A, Hurria A, Mohile SG, Luciani A, et al. End points and trial design in geriatric oncology research: a joint European organisation for research and treatment of cancer; alliance for clinical trials in oncology – international society of geriatric oncology position article. J Clin Oncol. 2013;31(29):3711–8.CrossRef
go back to reference Wildiers H, Heeren P, Puts M, et al. International society of geriatric oncology consensus on geriatric assessment in older patients with cancer. J Clin Oncol. 2014;32:2595–603.CrossRef Wildiers H, Heeren P, Puts M, et al. International society of geriatric oncology consensus on geriatric assessment in older patients with cancer. J Clin Oncol. 2014;32:2595–603.CrossRef
Metagegevens
Titel
Geriatrische oncologie
Auteurs
Prof. dr. J. E. A. Portielje
Dr. N. A. de Glas
Dr. F. van den Bos
Copyright
2020
Uitgeverij
Bohn Stafleu van Loghum
DOI
https://doi.org/10.1007/978-90-368-2449-1_15