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Gepubliceerd in: Journal of Autism and Developmental Disorders 3/2009

01-03-2009 | Original Paper

Gastrointestinal Symptoms in a Sample of Children with Pervasive Developmental Disorders

Auteurs: Roumen N. Nikolov, Karen E. Bearss, Jelle Lettinga, Craig Erickson, Maria Rodowski, Michael G. Aman, James T. McCracken, Christopher J. McDougle, Elaine Tierney, Benedetto Vitiello, L. Eugene Arnold, Bhavik Shah, David J. Posey, Louise Ritz, Lawrence Scahill

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 3/2009

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Abstract

Objective To evaluate gastrointestinal (GI) problems in a large, well-characterized sample of children with pervasive developmental disorders (PDDs). Methods One hundred seventy two children entering one of two trials conducted by the Research Units on Pediatric Psychopharmacology (RUPP) Autism Network were assessed comprehensively prior to starting treatment and classified with regard to GI symptoms. Results Thirty nine (22.7%) were positive for GI problems, primarily constipation and diarrhea. Those with GI problems were no different from subjects without GI problems in demographic characteristics, measures of adaptive functioning, or autism symptom severity. Compared to children without GI problems, those with GI problems showed greater symptom severity on measures of irritability, anxiety, and social withdrawal. Those with GI problems were also less likely to respond to treatment.

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Literatuur
go back to reference Aman, M. G., Singh, N. N., Stewart, A. W., & Field, C. J. (1985). Psychometric characteristics of the Aberrant Behavior Checklist. American Journal of Mental Deficiency, 89, 492–502. PubMed Aman, M. G., Singh, N. N., Stewart, A. W., & Field, C. J. (1985). Psychometric characteristics of the Aberrant Behavior Checklist. American Journal of Mental Deficiency, 89, 492–502. PubMed
go back to reference American Psychiatric Association. (2000). Diagnostic and Statistical Manual of Mental Disorders, Text revision (4th ed.). Washington, DC: American Psychiatric Association. American Psychiatric Association. (2000). Diagnostic and Statistical Manual of Mental Disorders, Text revision (4th ed.). Washington, DC: American Psychiatric Association.
go back to reference Arnold, L. E., Aman, M. G., Martin, A., Collier-Crespin, A., Vitiello, B., Tierney, E., et al. (2000). Assessment in multisite randomized clinical trials of patients with autistic disorder: The Autism RUPP Network Research Units on Pediatric Psychopharmacology. Journal of Autism and Developmental Disorders, 30, 99–111. doi: 10.​1023/​A:​1005451304303. PubMedCrossRef Arnold, L. E., Aman, M. G., Martin, A., Collier-Crespin, A., Vitiello, B., Tierney, E., et al. (2000). Assessment in multisite randomized clinical trials of patients with autistic disorder: The Autism RUPP Network Research Units on Pediatric Psychopharmacology. Journal of Autism and Developmental Disorders, 30, 99–111. doi: 10.​1023/​A:​1005451304303. PubMedCrossRef
go back to reference Autism Genome Project Consortium. (2007). Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nature Genetics, 39, 319–328. doi: 10.​1038/​ng1985. CrossRef Autism Genome Project Consortium. (2007). Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nature Genetics, 39, 319–328. doi: 10.​1038/​ng1985. CrossRef
go back to reference Black, C., Kaye, J. A., & Jick, H. (2002). Relation of childhood gastrointestinal disorders to autism: nested case-control study using data from the UK General Practice Research Database. BMJ (Clinical Research Ed.), 325, 419–421. doi: 10.​1136/​bmj.​325.​7361.​419. CrossRef Black, C., Kaye, J. A., & Jick, H. (2002). Relation of childhood gastrointestinal disorders to autism: nested case-control study using data from the UK General Practice Research Database. BMJ (Clinical Research Ed.), 325, 419–421. doi: 10.​1136/​bmj.​325.​7361.​419. CrossRef
go back to reference Brinkley, J., Nations, L., Abramson, R. K., Hall, A., Wright, H. H., Gabriels, R., et al. (2007). Factor analysis of the Aberrant Behavior Checklist in individuals with autism spectrum disorder. Journal of Autism and Developmental Disorders, 37, 1949–1959. doi: 10.​1007/​s10803-006-0327-3. PubMedCrossRef Brinkley, J., Nations, L., Abramson, R. K., Hall, A., Wright, H. H., Gabriels, R., et al. (2007). Factor analysis of the Aberrant Behavior Checklist in individuals with autism spectrum disorder. Journal of Autism and Developmental Disorders, 37, 1949–1959. doi: 10.​1007/​s10803-006-0327-3. PubMedCrossRef
go back to reference Brown, E. C., Aman, M. G., & Havercamp, S. M. (2002). Factor analysis and norms for parent ratings on the Aberrant Behavior Checklist-Community for young people in special education. Research in Developmental Disabilities, 23, 45–60. doi: 10.​1016/​S0891-4222(01)00091-9. PubMedCrossRef Brown, E. C., Aman, M. G., & Havercamp, S. M. (2002). Factor analysis and norms for parent ratings on the Aberrant Behavior Checklist-Community for young people in special education. Research in Developmental Disabilities, 23, 45–60. doi: 10.​1016/​S0891-4222(01)00091-9. PubMedCrossRef
go back to reference Erickson, C. A., Stigler, K. A., Corkins, M. R., Posey, D. J., Fitzgerald, J. F., & McDougle, C. J. (2005). Gastrointestinal factors in autistic disorder: A critical review. Journal of Autism and Developmental Disorders, 35, 713–727. doi: 10.​1007/​s10803-005-0019-4. PubMedCrossRef Erickson, C. A., Stigler, K. A., Corkins, M. R., Posey, D. J., Fitzgerald, J. F., & McDougle, C. J. (2005). Gastrointestinal factors in autistic disorder: A critical review. Journal of Autism and Developmental Disorders, 35, 713–727. doi: 10.​1007/​s10803-005-0019-4. PubMedCrossRef
go back to reference Fombonne, E. (2005). Epidemiology of autistic disorder and other pervasive developmental disorders. The Journal of Clinical Psychiatry, 66(Suppl), 3–8. PubMed Fombonne, E. (2005). Epidemiology of autistic disorder and other pervasive developmental disorders. The Journal of Clinical Psychiatry, 66(Suppl), 3–8. PubMed
go back to reference Fombonne, E., Zakarian, R., Bennett, A., Meng, L., & McLean-Heywood, D. (2006). Pervasive developmental disorders in Montreal, Quebac, Canada: Prevalence and links with Immunization. Pediatrics, 118, 139–150. CrossRef Fombonne, E., Zakarian, R., Bennett, A., Meng, L., & McLean-Heywood, D. (2006). Pervasive developmental disorders in Montreal, Quebac, Canada: Prevalence and links with Immunization. Pediatrics, 118, 139–150. CrossRef
go back to reference Jensen, J. A., & Armstrong, R. J. (1985). Slosson intelligence test for children and adults. East Aurora, NY: Slosson Educational Publications. Jensen, J. A., & Armstrong, R. J. (1985). Slosson intelligence test for children and adults. East Aurora, NY: Slosson Educational Publications.
go back to reference Lawler, C. P., Croen, L. A., Grether, J. K., & Van de Water, J. (2004). Identifying environmental contributions to autism: provocative clues and false leads. Mental Retardation and Developmental Disabilities Research Reviews, 10, 292–302. doi: 10.​1002/​mrdd.​20043. PubMedCrossRef Lawler, C. P., Croen, L. A., Grether, J. K., & Van de Water, J. (2004). Identifying environmental contributions to autism: provocative clues and false leads. Mental Retardation and Developmental Disabilities Research Reviews, 10, 292–302. doi: 10.​1002/​mrdd.​20043. PubMedCrossRef
go back to reference Lord, C., Pickles, A., McLennan, J., Rutter, M., Bregman, J., Folstein, S., et al. (1997). Diagnosing autism: Analyses of data from the Autism Diagnostic Interview. Journal of Autism and Developmental Disorders, 27, 501–517. doi: 10.​1023/​A:​1025873925661. PubMedCrossRef Lord, C., Pickles, A., McLennan, J., Rutter, M., Bregman, J., Folstein, S., et al. (1997). Diagnosing autism: Analyses of data from the Autism Diagnostic Interview. Journal of Autism and Developmental Disorders, 27, 501–517. doi: 10.​1023/​A:​1025873925661. PubMedCrossRef
go back to reference Lucarelli, S., Frediani, T., Zingoni, A. M., Ferruzzi, F., Giardini, O., Quintieri, F., et al. (1995). Food allergy and infantile autism. Panminerva Medica, 37, 137–141. PubMed Lucarelli, S., Frediani, T., Zingoni, A. M., Ferruzzi, F., Giardini, O., Quintieri, F., et al. (1995). Food allergy and infantile autism. Panminerva Medica, 37, 137–141. PubMed
go back to reference Mullen, E. (1995). The Mullen scales of early learning. Circle Pines, MN: American Guidance Service. Mullen, E. (1995). The Mullen scales of early learning. Circle Pines, MN: American Guidance Service.
go back to reference Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. (2002). Risperidone in children with autism and serious behavioral problems. The New England Journal of Medicine, 347, 314–321. doi: 10.​1056/​NEJMoa013171. CrossRef Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. (2002). Risperidone in children with autism and serious behavioral problems. The New England Journal of Medicine, 347, 314–321. doi: 10.​1056/​NEJMoa013171. CrossRef
go back to reference Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. (2005a). Randomized, controlled, crossover trial of methylphenidate in children with pervasive developmental disorders with hyperactivity. Archives of General Psychiatry, 62, 1266–1274. doi: 10.​1001/​archpsyc.​62.​11.​1266. CrossRef Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. (2005a). Randomized, controlled, crossover trial of methylphenidate in children with pervasive developmental disorders with hyperactivity. Archives of General Psychiatry, 62, 1266–1274. doi: 10.​1001/​archpsyc.​62.​11.​1266. CrossRef
go back to reference Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. (2005b). Risperidone treatment of autistic disorder: Longer term benefits and blinded discontinuation after six months. American Journal of Psychiatry, 162, 1361–1369. Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. (2005b). Risperidone treatment of autistic disorder: Longer term benefits and blinded discontinuation after six months. American Journal of Psychiatry, 162, 1361–1369.
go back to reference Roid, G. H., & Miller, L. J. (1997). Leiter international performance scale-revised: Examiner’s manual. Wood Dale, IL: Stoelting Co. Roid, G. H., & Miller, L. J. (1997). Leiter international performance scale-revised: Examiner’s manual. Wood Dale, IL: Stoelting Co.
go back to reference Scahill, L. (2005). Diagnosis and evaluation of pervasive developmental disorders. The Journal of Clinical Psychiatry, 66(Suppl), 19–25. PubMed Scahill, L. (2005). Diagnosis and evaluation of pervasive developmental disorders. The Journal of Clinical Psychiatry, 66(Suppl), 19–25. PubMed
go back to reference Sparrow, S., Balla, D., & Cicchetti, D. (1984). Vineland Adaptive Behavior Scales. Circle Pines, MN: American Guidance Service. Sparrow, S., Balla, D., & Cicchetti, D. (1984). Vineland Adaptive Behavior Scales. Circle Pines, MN: American Guidance Service.
go back to reference Sukhodolsky, D.G., Scahill, L., Gadow, K.D., Arnold, L.E., Aman, M.G., McDougle, C.J., et al. (2007). Parent-rated anxiety symptoms in children with pervasive developmental disorders: Frequency and association with core autism symptoms and cognitive functioning. Journal of Abnormal Child Psychology; Epub ahead of print. Sukhodolsky, D.G., Scahill, L., Gadow, K.D., Arnold, L.E., Aman, M.G., McDougle, C.J., et al. (2007). Parent-rated anxiety symptoms in children with pervasive developmental disorders: Frequency and association with core autism symptoms and cognitive functioning. Journal of Abnormal Child Psychology; Epub ahead of print.
go back to reference Taylor, B., Miller, E., Lingam, R., Andrews, N., Simmons, A., & Stowe, J. (2002). Measles, mumps and rubella vaccination and bowel problems or developmental regression in children with autism: Population study. British Medical Journal, 324, 393–396. doi: 10.​1136/​bmj.​324.​7334.​393. PubMedCrossRef Taylor, B., Miller, E., Lingam, R., Andrews, N., Simmons, A., & Stowe, J. (2002). Measles, mumps and rubella vaccination and bowel problems or developmental regression in children with autism: Population study. British Medical Journal, 324, 393–396. doi: 10.​1136/​bmj.​324.​7334.​393. PubMedCrossRef
go back to reference Valicenti-McDermott, M., McVicar, K., Rapin, I., Wershil, B. K., Cohen, H., & Shinnar, S. (2006). Frequency of gastrointestinal symptoms in children with autistic spectrum disorders and association with family history of autoimmune disease. Journal of Developmental and Behavioral Pediatrics, 27, S128–S136. doi: 10.​1097/​00004703-200604002-00011. PubMedCrossRef Valicenti-McDermott, M., McVicar, K., Rapin, I., Wershil, B. K., Cohen, H., & Shinnar, S. (2006). Frequency of gastrointestinal symptoms in children with autistic spectrum disorders and association with family history of autoimmune disease. Journal of Developmental and Behavioral Pediatrics, 27, S128–S136. doi: 10.​1097/​00004703-200604002-00011. PubMedCrossRef
go back to reference Wechsler, D. (1989). Manual for the Wechsler preschool and primary scale for children—revised. San Antonio, TX: Psychological Corporation. Wechsler, D. (1989). Manual for the Wechsler preschool and primary scale for children—revised. San Antonio, TX: Psychological Corporation.
go back to reference Wechsler, D. (1991). Manual for the Wechsler intelligence scale for children—Third edition. San Antonio, TX: Psychological Corporation. Wechsler, D. (1991). Manual for the Wechsler intelligence scale for children—Third edition. San Antonio, TX: Psychological Corporation.
Metagegevens
Titel
Gastrointestinal Symptoms in a Sample of Children with Pervasive Developmental Disorders
Auteurs
Roumen N. Nikolov
Karen E. Bearss
Jelle Lettinga
Craig Erickson
Maria Rodowski
Michael G. Aman
James T. McCracken
Christopher J. McDougle
Elaine Tierney
Benedetto Vitiello
L. Eugene Arnold
Bhavik Shah
David J. Posey
Louise Ritz
Lawrence Scahill
Publicatiedatum
01-03-2009
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 3/2009
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-008-0637-8