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Gepubliceerd in: Journal of Autism and Developmental Disorders 2/2011

01-02-2011 | Original Paper

From Bayes Through Marginal Utility to Effect Sizes: A Guide to Understanding the Clinical and Statistical Significance of the Results of Autism Research Findings

Auteurs: Domenic V. Cicchetti, Kathy Koenig, Ami Klin, Fred R. Volkmar, Rhea Paul, Sara Sparrow

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 2/2011

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Abstract

The objectives of this report are: (a) to trace the theoretical roots of the concept clinical significance that derives from Bayesian thinking, Marginal Utility/Diminishing Returns in Economics, and the “just noticeable difference”, in Psychophysics. These concepts then translated into: Effect Size (ES), strength of agreement, clinical significance, and related concepts, and made possible the development of Power Analysis; (b) to differentiate clinical significance from statistical significance; and (c) to demonstrate the utility of measures of ES and related concepts for enhancing the meaning of Autism research findings. These objectives are accomplished by applying criteria for estimating clinical significance, and related concepts, to a number of areas of autism research.

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Metagegevens
Titel
From Bayes Through Marginal Utility to Effect Sizes: A Guide to Understanding the Clinical and Statistical Significance of the Results of Autism Research Findings
Auteurs
Domenic V. Cicchetti
Kathy Koenig
Ami Klin
Fred R. Volkmar
Rhea Paul
Sara Sparrow
Publicatiedatum
01-02-2011
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 2/2011
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-010-1035-6