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2017 | OriginalPaper | Hoofdstuk

20. Farmacotherapie persoonlijkheidsstoornissen

Auteurs : Dr. Theo Ingenhoven, Dr. Thomas Rinne

Gepubliceerd in: Handboek persoonlijkheidspathologie

Uitgeverij: Bohn Stafleu van Loghum

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Samenvatting

Sinds de late jaren zeventig van de vorige eeuw is er voorzichtig optimisme ten aanzien van de effectiviteit van farmacotherapeutische interventies bij patiënten met een persoonlijkheidsstoornis, met name de borderlinepersoonlijkheidsstoornis (BPS). Er dient zich een groeiend aantal placebogecontroleerde gerandomiseerde studies aan waarin het effect van medicatie ten aanzien van specifieke symptomen van BPS in kaart wordt gebracht. Andere persoonlijkheidsstoornissen zijn veel minder onderzocht. Resultaten van placebogecontroleerd onderzoek maken duidelijk dat medicatie soms een behandeling kan ondersteunen, doordat op bepaalde symptoomgebieden van de persoonlijkheidsstoornissen winst te behalen valt, al is het maar in beperkte mate. In dit hoofdstuk bespreken we behandelalgoritmes van de meest toonaangevende behandelrichtlijnen voor persoonlijkheidsstoornissen (VS, Nederland, VK, Duitsland en Australië). We geven een kritisch overzicht van de gepubliceerde PC-RCT’s en meta-analyses die zich richten op specifieke symptoomdomeinen bij BPS (niet alleen primair op comorbide symptoomstoornissen). Op basis van deze uitkomsten wordt ten slotte een aantal aanbevelingen gepresenteerd.
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Metagegevens
Titel
Farmacotherapie persoonlijkheidsstoornissen
Auteurs
Dr. Theo Ingenhoven
Dr. Thomas Rinne
Copyright
2017
Uitgeverij
Bohn Stafleu van Loghum
DOI
https://doi.org/10.1007/978-90-368-0931-3_20