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Gepubliceerd in: Journal of Autism and Developmental Disorders 3/2006

01-04-2006

Familial Autoimmune Thyroid Disease as a Risk Factor for Regression in Children with Autism Spectrum Disorder: A CPEA Study

Auteurs: Cynthia A. Molloy, Ardythe L. Morrow, Jareen Meinzen-Derr, Geraldine Dawson, Raphael Bernier, Michelle Dunn, Susan L. Hyman, William M. McMahon, Julie Goudie-Nice, Susan Hepburn, Nancy Minshew, Sally Rogers, Marian Sigman, M. Anne Spence, Helen Tager-Flusberg, Fred R. Volkmar, Catherine Lord

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 3/2006

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Abstract

A multicenter study of 308 children with Autism Spectrum Disorder (ASD) was conducted through the Collaborative Programs of Excellence in Autism (CPEA), sponsored by the National Institute of Child Health and Human Development, to compare the family history of autoimmune disorders in children with ASD with and without a history of regression. A history of regression was determined from the results of the Autism Diagnostic Interview-Revised (ADI-R). Family history of autoimmune disorders was obtained by telephone interview. Regression was significantly associated with a family history of autoimmune disorders (adjusted OR=1.89; 95% CI: 1.17, 3.10). The only specific autoimmune disorder found to be associated with regression was autoimmune thyroid disease (adjusted OR=2.09; 95% CI: 1.28, 3.41).
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Metagegevens
Titel
Familial Autoimmune Thyroid Disease as a Risk Factor for Regression in Children with Autism Spectrum Disorder: A CPEA Study
Auteurs
Cynthia A. Molloy
Ardythe L. Morrow
Jareen Meinzen-Derr
Geraldine Dawson
Raphael Bernier
Michelle Dunn
Susan L. Hyman
William M. McMahon
Julie Goudie-Nice
Susan Hepburn
Nancy Minshew
Sally Rogers
Marian Sigman
M. Anne Spence
Helen Tager-Flusberg
Fred R. Volkmar
Catherine Lord
Publicatiedatum
01-04-2006
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 3/2006
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-005-0071-0