Swipe om te navigeren naar een ander artikel
Kidney transplantation improves the quality of life of end-stage renal disease patients. The quality of life benefits, however, pertain to patients on average, not to all transplant recipients. The aim of this study was to identify factors associated with health-related quality of life after kidney transplantation.
Population-based study with a cross-sectional design was carried out and quality of life was assessed by SF-36 Health Survey Version 1. A multivariate linear regression model was constructed with sociodemographic, clinical and laboratory data as independent variables.
Two hundred and seventy-two kidney recipients with a functioning graft were analyzed. Hypertension, diabetes, higher serum creatinine and lower hematocrit were independently and significantly associated with lower scores for the SF-36 oblique physical component summary (PCSc). The final regression model explained 11% of the PCSc variance. The scores of oblique mental component summary (MCSc) were worse for females, patients with a lower income, unemployed and patients with a higher serum creatinine. The regression model explained 9% of the MCSc variance.
Among the studied variables, comorbidity and graft function were the main factors associated with the PCSc, and sociodemographic variables and graft function were the main determinants of MCSc. Despite comprehensive, the final regression models explained only a little part of the heath-related quality of life variance. Additional factors, such as personal, environmental and clinical ones might influence quality of life perceived by the patients after kidney transplantation.
Log in om toegang te krijgen
Met onderstaand(e) abonnement(en) heeft u direct toegang:
Liem, Y. S., Bosch, J. L., Arends, L. R., Heijenbrok-Kal, M. H., & Hinink, M. G. M. (2007). Quality of life assessed with the medical outcomes study short form 36-item health survey of patients on renal replacement therapy: A systematic review and meta-analysis. Value in Health, 10(5), 390–397. PubMedCrossRef
Rebollo, P., Gonzalez, M. P., Bobes, J., Saiz, P., & Ortega, F. (2000). Interpretación de los resultados de la calidad de vida relacionada con la salud de pacientes en terapia substitutiva de la insuficiencia renal terminal. Nefrologia, 20, 431–439. PubMed
Zimmermann, P. R., Poli de Figueiredo, C. E., & Fonseca, N. A. (2001). Depression, anxiety and adjustment in renal replacement therapy: A quality of life assessment. Clinical Nephrology, 56(5), 387–390. PubMed
Cohen, J., Cohen, P., West, S. G., & Aiken, L. S. (2003). Applied multiple regression/correlation analysis for the behavioral sciences (3rd ed.). Mahwah, NJ: Lawrence Earlbaum Associates.
Ciconelli, R. M., Ferraz, M. B., Santos, W., Meinão, I., & Quaresma, M. R. (1999). Brazilian-Portuguese version of the SF-36. A reliable and valid quality of life outcome measure. Revista Brasileira De Reumatologia, 39, 143–150.
Hosmer, D. W., & Lemeshow, S. (2000). Applied logistic regression. New York: Wiley. CrossRef
Butt, Z., Yount, S. E., Caicedo, J. C., Abecassis, M. M., & Cella D. (2008). Quality of life assessment in renal transplant: Review and future directions. Clinical Transplantation, 22(3), 292–303. PubMed
Oberbauer, R., Hutchison, B., Eris, J., Arias, M., Claesson, K., Mota, A., et al. (2003). Health-related quality-of-life outcomes of sirolimus-treated kidney transplant patients after elimination of cyclosporin A: Results of a 2-year randomized clinical trial. Transplantation, 75, 1277–1285. PubMedCrossRef
Ware, J. E., Kosinski, M., & Keller, S. D. (1994). SF-36 physical and mental health summary scales: A user’s manual. Boston, MA: The Health Institute.
Hathaway, D. K., Winsett, R. P., & Johnson, C. (1998). Post kidney transplant quality of life prediction models. Clinical Transplantation, 12, 168–174. PubMed
Julius, M., Hawthorne, V. M., & Carpentier Alting, P. (1989). Independence in activities of daily living for end-stage renal patients: Biomedical and demographic correlates. American Journal of Kidney Diseases, 13, 61–69. PubMed
Baiardi, F., Degli, E. E., Cocchi, R., Fabbri, A., Sturani, A., Valpiani, G., et al. (2002). Effects of clinical and individual variables on quality of life in chronic renal failure patients. Journal of Nephrology, 15(1), 61–67. PubMed
Keogh, A. M., & Feehally, J. (1999). A quantitative study comparing adjustment and acceptance of illness in adults on renal replacement therapy. ANNA Journal, 26, 471–477. PubMed
Johnson, C. D., Wicks, M. N., Milstead, J., Hartwig, M., & Hathaway, D. K. (1998). Racial and gender differences in quality of life following kidney transplantation. Journal of Nursing Scholarship, 30, 125–130. CrossRef
McCabe, M., & de Judicibus, M. (2005). The effects of economic disadvantage on psychological well-being and quality of life among people with multiple sclerosis. Journal of Health Psychology, 10, 163–173. CrossRef
Wubben, D., & Porterfield, D. (2005). Health-related quality of life among North Carolina adults with diabetes mellitus. North Carolina Medical Journal, 66, 179–185. PubMed
Vanderbilt.edu [homepage na Internet]. Nashville: Vanderbilt University Medical Center; c 2004 [atualizada em 2005 Feb 02; acesso em 2008 Jan 10]. Available at: www.mc.vanderbilt.edu/transplant/html/supportservices.html.
Seršić, D. M., & Vuletić, G. (2006). Psychometric evaluation and establishing norms of croatian SF-36 health survey: Framework for subjective health research. Croatian Medical Journal, 47(1), 95–102.
Behavioral Epidemiology Unit. South Australian population norms for the Short Form 36 (SF-36) Health Status Questionnaire. Adelaide, South Australian Health Commission, August 1995.
Aaronson, N. K., Muller, M., Cohen, P. D., Essink-Bot, M. L., Fekkes, M., Sanderman, R., et al. (1998). Translation, validation, and norming of the Dutch language version of the SF-36 health survey in community and chronic disease populations. Journal of Clinical Epidemiology, 51, 1055–1068. PubMedCrossRef
Phipps, S. (2003). The impact of poverty on health. Ottawa: Canadian Institute for Health Information.
Ortega, F., Valdés, C., & Ortega, T. (2007). Quality of life after solid organ transplantation. Transplantation Reviews, 21, 155–170. CrossRef
- Factors associated with health-related quality of life after successful kidney transplantation: a population-based study
Stela S. Marini
Rafael H. Gomes
Franklin C. Barcellos
Maria Claudia C. Irigoyen
- Springer Netherlands