Skip to main content
Top
Gepubliceerd in: Journal of Autism and Developmental Disorders 11/2021

03-01-2021 | Original Paper

Factors Associated with a Delayed Autism Spectrum Disorder Diagnosis in Children Previously Assessed on Suspicion of Autism

Auteurs: Sara Højslev Avlund, Per Hove Thomsen, Diana Schendel, Meta Jørgensen, Anders Helles Carlsen, Loa Clausen

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 11/2021

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

This study aimed to investigate factors associated with a delayed autism spectrum (ASD) diagnosis when compared to children with either no or early ASD diagnosis. Among 893 children assessed for ASD before age 8, 39% had no ASD at baseline, of which 21% received a later ASD diagnosis. Autism symptoms, diagnostic history of other developmental disorders, cognitive ability, and socioeconomic factors were associated with delayed ASD. Autism Diagnostic Observation Schedule (ADOS) scores in delayed ASD fell between early and no ASD. Other developmental disorders, time and clinical trends like ADOS use and low parental education distinguished delayed and early ASD, whereas higher frequency of IQ < 70 at baseline and a diagnosis of emotional disorders during follow-up distinguished delayed and no ASD.
Bijlagen
Alleen toegankelijk voor geautoriseerde gebruikers
Literatuur
go back to reference American Psychiatric, A. (1994). Diagnostic and statistical manual of mental disorders: DSM-IV (4th ed.). Washington, DC: American Psychiatric Association. American Psychiatric, A. (1994). Diagnostic and statistical manual of mental disorders: DSM-IV (4th ed.). Washington, DC: American Psychiatric Association.
go back to reference American Psychiatric, A. (2013). Diagnostic and Statistical Manual of Mental Disorders: DSM-5 (5th ed. Arlington ed.): American Psyciatric Publishing. American Psychiatric, A. (2013). Diagnostic and Statistical Manual of Mental Disorders: DSM-5 (5th ed. Arlington ed.): American Psyciatric Publishing.
go back to reference Andersen, T. F., Madsen, M., Jørgensen, J., Mellemkjoer, L., & Olsen, J. H. (1999). The Danish National Hospital Register. A valuable source of data for modern health sciences. Danish Medical Bulletin, 46(3), 263–268.PubMed Andersen, T. F., Madsen, M., Jørgensen, J., Mellemkjoer, L., & Olsen, J. H. (1999). The Danish National Hospital Register. A valuable source of data for modern health sciences. Danish Medical Bulletin, 46(3), 263–268.PubMed
go back to reference Avlund, S. H., Thomsen, P. H., Schendel, D., Jørgensen, M., & Clausen, L. (2020). Time trends in diagnostics and clinical features of young children referred on suspicion of autism: A population-based clinical cohort study, 2000–2010. Journal of Autism and Developmental Disorders. https://doi.org/10.1007/s10803-020-04555-8.CrossRef Avlund, S. H., Thomsen, P. H., Schendel, D., Jørgensen, M., & Clausen, L. (2020). Time trends in diagnostics and clinical features of young children referred on suspicion of autism: A population-based clinical cohort study, 2000–2010. Journal of Autism and Developmental Disorders. https://​doi.​org/​10.​1007/​s10803-020-04555-8.CrossRef
go back to reference Dalsgaard, S., Thorsteinsson, E., Trabjerg, B. B., Schullehner, J., Plana-Ripoll, O., Brikell, I., … Pedersen, C. B. (2019). Incidence rates and cumulative incidences of the full spectrum of diagnosed mental disorders in childhood and adolescence. JAMA Psychiatry, 77(2), 155–164. https://doi.org/10.1001/jamapsychiatry.2019.3523. Dalsgaard, S., Thorsteinsson, E., Trabjerg, B. B., Schullehner, J., Plana-Ripoll, O., Brikell, I., … Pedersen, C. B. (2019). Incidence rates and cumulative incidences of the full spectrum of diagnosed mental disorders in childhood and adolescence. JAMA Psychiatry, 77(2), 155–164. https://​doi.​org/​10.​1001/​jamapsychiatry.​2019.​3523.
go back to reference Grzadzinski, R., Dick, C., Lord, C., & Bishop, S. (2016). Parent-reported and clinician-observed autism spectrum disorder (ASD) symptoms in children with attention deficit/hyperactivity disorder (ADHD): implications for practice under DSM-5. Molecular Autism. eCollection 2016. https://doi.org/10.1186/s13229-016-0072-1. Grzadzinski, R., Dick, C., Lord, C., & Bishop, S. (2016). Parent-reported and clinician-observed autism spectrum disorder (ASD) symptoms in children with attention deficit/hyperactivity disorder (ADHD): implications for practice under DSM-5. Molecular Autism. eCollection 2016. https://​doi.​org/​10.​1186/​s13229-016-0072-1.
go back to reference Lai, M. C., Kassee, C., Besney, R., Bonato, S., Hull, L., Mandy, W., … Ameis, S. H. (2019). Prevalence of co-occurring mental health diagnoses in the autism population: a systematic review and meta-analysis. The Lancet Psychiatry, 6(10), 819–829. Lai, M. C., Kassee, C., Besney, R., Bonato, S., Hull, L., Mandy, W., … Ameis, S. H. (2019). Prevalence of co-occurring mental health diagnoses in the autism population: a systematic review and meta-analysis. The Lancet Psychiatry, 6(10), 819–829.
go back to reference Lauritsen, M. B., Jørgensen, M., Madsen, K. M., Lemcke, S., Toft, S., Grove, J., … Thorsen, P. (2010). Validity of childhood autism in the danish psychiatric central register: Findings from a Cohort sample born 1990–1999. Journal of Autism and Developmental Disorders, 40(2), 139–148. https://doi.org/10.1007/s10803-009-0818-0. Lauritsen, M. B., Jørgensen, M., Madsen, K. M., Lemcke, S., Toft, S., Grove, J., … Thorsen, P. (2010). Validity of childhood autism in the danish psychiatric central register: Findings from a Cohort sample born 1990–1999. Journal of Autism and Developmental Disorders, 40(2), 139–148. https://​doi.​org/​10.​1007/​s10803-009-0818-0.
go back to reference Lord, C., Elsabbagh, M., Baird, G., & Veenstra-Vanderweele, J. (2018). Autism spectrum disorder. Lancet (London, England), 392(10146), 508–520.CrossRef Lord, C., Elsabbagh, M., Baird, G., & Veenstra-Vanderweele, J. (2018). Autism spectrum disorder. Lancet (London, England), 392(10146), 508–520.CrossRef
go back to reference Lord, C., Risi, S., Lambrecht, L., Cook Jr, E. H., Leventhal, B. L., Dilavore, P. C., … Rutter, M. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223. https://doi.org/10.1023/A:1005592401947. Lord, C., Risi, S., Lambrecht, L., Cook Jr, E. H., Leventhal, B. L., Dilavore, P. C., … Rutter, M. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223. https://​doi.​org/​10.​1023/​A:​1005592401947.
go back to reference Lord, C., Rutter, M., Dilavore, P. C., Risi, S., Gotham, K., & Bishop, S. L. (2013). Autism Diagnostic Observation Schedule 2nd ed. (ADOS-2). Danish version. Lord, C., Rutter, M., Dilavore, P. C., Risi, S., Gotham, K., & Bishop, S. L. (2013). Autism Diagnostic Observation Schedule 2nd ed. (ADOS-2). Danish version.
go back to reference Mullen, E. M. (1995). Mullen scales of early learning (MSEL). Circle Pines, MN: American Guidance Service. Mullen, E. M. (1995). Mullen scales of early learning (MSEL). Circle Pines, MN: American Guidance Service.
go back to reference Ozonoff, S., Young, G. S., Brian, J., Charman, T., Shephard, E., Solish, A., & Zwaigenbaum, L. (2018). Diagnosis of autism spectrum disorder after age 5 in children evaluated longitudinally since infancy. Journal of the American Academy of Child and Adolescent Psychiatry, 57(11), 849-857.e842.CrossRef Ozonoff, S., Young, G. S., Brian, J., Charman, T., Shephard, E., Solish, A., & Zwaigenbaum, L. (2018). Diagnosis of autism spectrum disorder after age 5 in children evaluated longitudinally since infancy. Journal of the American Academy of Child and Adolescent Psychiatry, 57(11), 849-857.e842.CrossRef
go back to reference Pedersen, A. L., Pettygrove, S., Lu, Z., Andrews, J., Meaney, F. J., Kurzius-Spencer, M., … Cunniff, C. (2017). DSM criteria that best differentiate intellectual disability from autism spectrum disorder. Child Psychiatry & Human Development, 48(4), 537-545. https://doi.org/10.1007/s10578-016-0681-0. Pedersen, A. L., Pettygrove, S., Lu, Z., Andrews, J., Meaney, F. J., Kurzius-Spencer, M., … Cunniff, C. (2017). DSM criteria that best differentiate intellectual disability from autism spectrum disorder. Child Psychiatry & Human Development, 48(4), 537-545. https://​doi.​org/​10.​1007/​s10578-016-0681-0.
go back to reference Sheldrick, R. C., Maye, M. P., & Carter, A. S. (2017). Age at first identification of autism spectrum disorder: An analysis of two US Surveys. Journal of the American Academy of Child and Adolescent Psychiatry, 56(4), 313–320.CrossRef Sheldrick, R. C., Maye, M. P., & Carter, A. S. (2017). Age at first identification of autism spectrum disorder: An analysis of two US Surveys. Journal of the American Academy of Child and Adolescent Psychiatry, 56(4), 313–320.CrossRef
go back to reference Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child and Adolescent Psychiatry, 47(8), 921–929. https://doi.org/10.1097/CHI.0b013e318179964f.CrossRefPubMed Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child and Adolescent Psychiatry, 47(8), 921–929. https://​doi.​org/​10.​1097/​CHI.​0b013e318179964f​.CrossRefPubMed
go back to reference Sinzig, J., Walter, D., & Doepfner, M. (2009). Attention deficit/hyperactivity disorder in children and adolescents with autism spectrum disorder: Symptom or syndrome? Journal of Attention Disorders, 13(2), 117–126.CrossRef Sinzig, J., Walter, D., & Doepfner, M. (2009). Attention deficit/hyperactivity disorder in children and adolescents with autism spectrum disorder: Symptom or syndrome? Journal of Attention Disorders, 13(2), 117–126.CrossRef
go back to reference Snijders, J. T., Tellegen, P. J., & Laros, J. A. (1997). Snijders-Oomen Nonverbaler Intelligenztest SON-R 5.5-17. Göttingen: Hogrefe. Snijders, J. T., Tellegen, P. J., & Laros, J. A. (1997). Snijders-Oomen Nonverbaler Intelligenztest SON-R 5.5-17. Göttingen: Hogrefe.
go back to reference Wechsler, D. (1991). Wechsler intelligence scale for children (3rd ed.). San Antonio, TX: Psychological Corporation. Wechsler, D. (1991). Wechsler intelligence scale for children (3rd ed.). San Antonio, TX: Psychological Corporation.
go back to reference Wechsler, D. (2002). Wechsler preschool and primary scale of intelligence (3rd ed.). San Antonio, TX: Psychological Corporation. Wechsler, D. (2002). Wechsler preschool and primary scale of intelligence (3rd ed.). San Antonio, TX: Psychological Corporation.
go back to reference World Health Organisation. (1992). The ICD-10 Classification of Mental Health and Behavioral Disorders. Diagnostic criteria for research. Geneva: World Health Organisation. World Health Organisation. (1992). The ICD-10 Classification of Mental Health and Behavioral Disorders. Diagnostic criteria for research. Geneva: World Health Organisation.
Metagegevens
Titel
Factors Associated with a Delayed Autism Spectrum Disorder Diagnosis in Children Previously Assessed on Suspicion of Autism
Auteurs
Sara Højslev Avlund
Per Hove Thomsen
Diana Schendel
Meta Jørgensen
Anders Helles Carlsen
Loa Clausen
Publicatiedatum
03-01-2021
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 11/2021
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-020-04849-x

Andere artikelen Uitgave 11/2021

Journal of Autism and Developmental Disorders 11/2021 Naar de uitgave