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01-02-2015 | Original Paper

Eyeblink Conditioning: A Non-invasive Biomarker for Neurodevelopmental Disorders

Auteurs: Bethany C. Reeb-Sutherland, Nathan A. Fox

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 2/2015

Abstract

Eyeblink conditioning (EBC) is a classical conditioning paradigm typically used to study the underlying neural processes of learning and memory. EBC has a well-defined neural circuitry, is non-invasive, and can be employed in human infants shortly after birth making it an ideal tool to use in both developing and special populations. In addition, abnormalities in the cerebellum, a region of the brain highly involved in EBC, have been implicated in a number of neurodevelopmental disorders including autism spectrum disorders (ASDs). In the current paper, we review studies that have employed EBC as a biomarker for several neurodevelopmental disorders including fetal alcohol syndrome, Down syndrome, fragile X syndrome, attention deficit/hyperactivity disorder, dyslexia, specific language impairment, and schizophrenia. In addition, we discuss the benefits of using such a tool in individuals with ASD.

vorige artikel An Electrophysiological Investigation of Interhemispheric Transfer Time in Children and Adolescents with High-Functioning Autism Spectrum Disorders

volgende artikel Neuromagnetic Oscillations Predict Evoked-Response Latency Delays and Core Language Deficits in Autism Spectrum Disorders

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Titel: Eyeblink Conditioning: A Non-invasive Biomarker for Neurodevelopmental Disorders
Auteurs: Bethany C. Reeb-Sutherland
Nathan A. Fox
Publicatiedatum: 01-02-2015
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 2/2015
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-013-1905-9

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