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01-02-2015 | Original Paper | Uitgave 2/2015

Eyeblink Conditioning: A Non-invasive Biomarker for Neurodevelopmental Disorders

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 2/2015

Auteurs:: Bethany C. Reeb-Sutherland, Nathan A. Fox

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Abstract

Eyeblink conditioning (EBC) is a classical conditioning paradigm typically used to study the underlying neural processes of learning and memory. EBC has a well-defined neural circuitry, is non-invasive, and can be employed in human infants shortly after birth making it an ideal tool to use in both developing and special populations. In addition, abnormalities in the cerebellum, a region of the brain highly involved in EBC, have been implicated in a number of neurodevelopmental disorders including autism spectrum disorders (ASDs). In the current paper, we review studies that have employed EBC as a biomarker for several neurodevelopmental disorders including fetal alcohol syndrome, Down syndrome, fragile X syndrome, attention deficit/hyperactivity disorder, dyslexia, specific language impairment, and schizophrenia. In addition, we discuss the benefits of using such a tool in individuals with ASD.

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Titel: Eyeblink Conditioning: A Non-invasive Biomarker for Neurodevelopmental Disorders
Auteurs:: Bethany C. Reeb-Sutherland
Nathan A. Fox
Publicatiedatum: 01-02-2015
DOI: https://doi.org/10.1007/s10803-013-1905-9
Uitgeverij: Springer US
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 2/2015
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

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Eyeblink Conditioning: A Non-invasive Biomarker for Neurodevelopmental Disorders

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Bohn Stafleu van Loghum

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Abstract

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Andere artikelen Uitgave 2/2015

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Attenuated Auditory Event-Related Potentials and Associations with Atypical Sensory Response Patterns in Children with Autism

Guidelines and Best Practices for Electrophysiological Data Collection, Analysis and Reporting in Autism

Lower Electrodermal Activity to Acute Stress in Caregivers of People with Autism Spectrum Disorder: An Adaptive Habituation to Stress

Alpha Asymmetry in Infants at Risk for Autism Spectrum Disorders