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Gepubliceerd in: Journal of Autism and Developmental Disorders 10/2013

01-10-2013 | Original Paper

Exploring the Manifestations of Anxiety in Children with Autism Spectrum Disorders

Auteurs: Victoria Hallett, Luc Lecavalier, Denis G. Sukhodolsky, Noreen Cipriano, Michael G. Aman, James T. McCracken, Christopher J. McDougle, Elaine Tierney, Bryan H. King, Eric Hollander, Linmarie Sikich, Joel Bregman, Evdokia Anagnostou, Craig Donnelly, Lily Katsovich, Kimberly Dukes, Benedetto Vitiello, Kenneth Gadow, Lawrence Scahill

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 10/2013

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Abstract

This study explores the manifestation and measurement of anxiety symptoms in 415 children with ASDs on a 20-item, parent-rated, DSM-IV referenced anxiety scale. In both high and low-functioning children (IQ above vs. below 70), commonly endorsed items assessed restlessness, tension and sleep difficulties. Items requiring verbal expression of worry by the child were rarely endorsed. Higher anxiety was associated with functional language, IQ above 70 and higher scores on several other behavioral measures. Four underlying factors emerged: Generalized Anxiety, Separation Anxiety, Social Anxiety and Over-arousal. Our findings extend our understanding of anxiety across IQ in ASD and provide guidance for improving anxiety outcome measurement.
Literatuur
go back to reference Aman, M. G., McDougle, C. J., Scahill, L., Handen, B., Arnold, L. E., Johnson, C., et al. (2009). Medication and parent training in children with pervasive developmental disorders and serious behavior problems: Results from a randomized clinical trial. Journal of the American Academy of Child and Adolescent Psychiatry, 48(12),1143–1154. Aman, M. G., McDougle, C. J., Scahill, L., Handen, B., Arnold, L. E., Johnson, C., et al. (2009). Medication and parent training in children with pervasive developmental disorders and serious behavior problems: Results from a randomized clinical trial. Journal of the American Academy of Child and Adolescent Psychiatry, 48(12),1143–1154.
go back to reference Aman, M. G., Singh, N. N., Stewart, A. W., & Field, C. J. (1985). The aberrant behavior checklist: A behavior rating scale for the assessment of treatment effects. American journal of mental deficiency, 89(5), 485–491.PubMed Aman, M. G., Singh, N. N., Stewart, A. W., & Field, C. J. (1985). The aberrant behavior checklist: A behavior rating scale for the assessment of treatment effects. American journal of mental deficiency, 89(5), 485–491.PubMed
go back to reference American Psychiatric Association. (1980). Diagnostic and statistical manual of mental disorders (3rd ed.). Washington, DC: American Psychiatric Association. American Psychiatric Association. (1980). Diagnostic and statistical manual of mental disorders (3rd ed.). Washington, DC: American Psychiatric Association.
go back to reference American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: American Psychiatric Association. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: American Psychiatric Association.
go back to reference Brown, E. C., Aman, M. G., & Havercamp, S. M. (2002). Factor analysis and norms for parent ratings on the Aberrant Behavior Checklist-Community for young people in special education. Research in Developmental Disabilities, 23(1), 45–60.PubMedCrossRef Brown, E. C., Aman, M. G., & Havercamp, S. M. (2002). Factor analysis and norms for parent ratings on the Aberrant Behavior Checklist-Community for young people in special education. Research in Developmental Disabilities, 23(1), 45–60.PubMedCrossRef
go back to reference Browne, M. W., Cudeck, R., Tateneni, K., & Mels, G. (2009). CEFA: Comprehensive exploratory factor analysis, version 3.04. [Computer Software and Manual]. Browne, M. W., Cudeck, R., Tateneni, K., & Mels, G. (2009). CEFA: Comprehensive exploratory factor analysis, version 3.04. [Computer Software and Manual].
go back to reference Canitano, R. (2006). Self injurious behavior in autism: Clinical aspects and treatment with risperidone. Journal of neural transmission, 113(3), 425–431.PubMedCrossRef Canitano, R. (2006). Self injurious behavior in autism: Clinical aspects and treatment with risperidone. Journal of neural transmission, 113(3), 425–431.PubMedCrossRef
go back to reference Costello, E. J., Egger, H. L., & Angold, A. (2005). The developmental epidemiology of anxiety disorders: Phenomenology, prevalence, and comorbidity. Child and adolescent psychiatric clinics of North America, 14(4), 631–648.PubMedCrossRef Costello, E. J., Egger, H. L., & Angold, A. (2005). The developmental epidemiology of anxiety disorders: Phenomenology, prevalence, and comorbidity. Child and adolescent psychiatric clinics of North America, 14(4), 631–648.PubMedCrossRef
go back to reference Gadow, K. D., DeVincent, C. J., Pomeroy, J., & Azizian, A. (2004). Psychiatric symptoms in preschool children with PDD and clinic and comparison samples. Journal of Autism and Developmental Disorders, 34(4), 379–393.PubMedCrossRef Gadow, K. D., DeVincent, C. J., Pomeroy, J., & Azizian, A. (2004). Psychiatric symptoms in preschool children with PDD and clinic and comparison samples. Journal of Autism and Developmental Disorders, 34(4), 379–393.PubMedCrossRef
go back to reference Gadow, K. D., Devincent, C. J., Pomeroy, J., & Azizian, A. (2005). Comparison of DSM-IV symptoms in elementary school-age children with PDD versus clinic and community samples. Autism: The International Journal of Research and Practice, 9(4), 392–415.CrossRef Gadow, K. D., Devincent, C. J., Pomeroy, J., & Azizian, A. (2005). Comparison of DSM-IV symptoms in elementary school-age children with PDD versus clinic and community samples. Autism: The International Journal of Research and Practice, 9(4), 392–415.CrossRef
go back to reference Gadow, K. D., & Sprafkin, J. (1998). Adolescent symptom inventory-4 norms manual (Vol. Stony Brook, NY: Checkmate Plus). Stony Brook, NY: Checkmate Plus. Gadow, K. D., & Sprafkin, J. (1998). Adolescent symptom inventory-4 norms manual (Vol. Stony Brook, NY: Checkmate Plus). Stony Brook, NY: Checkmate Plus.
go back to reference Gadow, K. D., & Sprafkin, J. (2002). Child symptom inventory-4 screening and norms manual. Stony Brook, NY: Checkmate Plus. Gadow, K. D., & Sprafkin, J. (2002). Child symptom inventory-4 screening and norms manual. Stony Brook, NY: Checkmate Plus.
go back to reference Goodman, W. K., Price, L. H., Rasmussen, S. A., Mazure, C., Fleischmann, R. L., Hill, C. L., et al. (1989). The yale-brown obsessive compulsive scale: 1. Development, use, and reliability. Archives of General Psychiatry, 46(11), 1006–1011.PubMedCrossRef Goodman, W. K., Price, L. H., Rasmussen, S. A., Mazure, C., Fleischmann, R. L., Hill, C. L., et al. (1989). The yale-brown obsessive compulsive scale: 1. Development, use, and reliability. Archives of General Psychiatry, 46(11), 1006–1011.PubMedCrossRef
go back to reference Ivarsson, T., & Melin, K. (2008). Autism spectrum traits in children and adolescents with obsessive-compulsive disorder (OCD). Journal of Anxiety Disorders, 22(6), 969–978.PubMedCrossRef Ivarsson, T., & Melin, K. (2008). Autism spectrum traits in children and adolescents with obsessive-compulsive disorder (OCD). Journal of Anxiety Disorders, 22(6), 969–978.PubMedCrossRef
go back to reference Jensen, J. A., & Armstrong, R. J. (1985). Slosson intelligence test for children and adults. East Aurora, NY: Slosson Educational Publications. Jensen, J. A., & Armstrong, R. J. (1985). Slosson intelligence test for children and adults. East Aurora, NY: Slosson Educational Publications.
go back to reference Jöreskog, K. G., & Sörbom, D. (2004). LISREL 8.7 for Windows [Computer Software]. Lincolnwood, IL: Scientific Software International, Inc. Jöreskog, K. G., & Sörbom, D. (2004). LISREL 8.7 for Windows [Computer Software]. Lincolnwood, IL: Scientific Software International, Inc.
go back to reference Kanner, L. (1943). Autistic disturbances of affective contact. Nervous Child, 2(3), 217–250. Kanner, L. (1943). Autistic disturbances of affective contact. Nervous Child, 2(3), 217–250.
go back to reference Kim, J. A., Szatmari, P., Bryson, S. E., Streiner, D. L., & Wilson, F. J. (2000). The prevalence of anxiety and mood problems among children with autism and Asperger syndrome. Autism: The International Journal of Research and Practice, 4(2), 117–132.CrossRef Kim, J. A., Szatmari, P., Bryson, S. E., Streiner, D. L., & Wilson, F. J. (2000). The prevalence of anxiety and mood problems among children with autism and Asperger syndrome. Autism: The International Journal of Research and Practice, 4(2), 117–132.CrossRef
go back to reference King, B. H., Hollander, E., Sikich, L., McCracken, J. T., Scahill, L., Bregman, J. D., et al. (2009). Lack of efficacy of citalopram in children with autism spectrum disorders and high levels of repetitive behavior: Citalopram ineffective in children with autism. Archives of General Psychiatry, 66(6), 583–590.PubMedCrossRef King, B. H., Hollander, E., Sikich, L., McCracken, J. T., Scahill, L., Bregman, J. D., et al. (2009). Lack of efficacy of citalopram in children with autism spectrum disorders and high levels of repetitive behavior: Citalopram ineffective in children with autism. Archives of General Psychiatry, 66(6), 583–590.PubMedCrossRef
go back to reference Le Couteur, A., Lord, C., & Rutter, M. (2003). Autism diagnostic interview-revised. Los Angeles: Western Psychological Services. Le Couteur, A., Lord, C., & Rutter, M. (2003). Autism diagnostic interview-revised. Los Angeles: Western Psychological Services.
go back to reference Lecavalier, L. (2006). Behavioral and emotional problems in young people with pervasive developmental disorders: Relative prevalence, effects of subject characteristics, and empirical classification. Journal of Autism and Developmental Disorders, 36(8), 1101–1114.PubMedCrossRef Lecavalier, L. (2006). Behavioral and emotional problems in young people with pervasive developmental disorders: Relative prevalence, effects of subject characteristics, and empirical classification. Journal of Autism and Developmental Disorders, 36(8), 1101–1114.PubMedCrossRef
go back to reference Marshburn, E. C., & Aman, M. G. (1992). Factor validity and norms for the aberrant behavior checklist in a community sample of children with mental-retardation. Journal of Autism and Developmental Disorders, 22(3), 357–373.PubMedCrossRef Marshburn, E. C., & Aman, M. G. (1992). Factor validity and norms for the aberrant behavior checklist in a community sample of children with mental-retardation. Journal of Autism and Developmental Disorders, 22(3), 357–373.PubMedCrossRef
go back to reference Mazurek, M. O., & Kanne, S. M. (2010). Friendship and internalizing symptoms among children and adolescents with ASD. Journal of Autism and Developmental Disorders, 40(12), 1512–1520.PubMedCrossRef Mazurek, M. O., & Kanne, S. M. (2010). Friendship and internalizing symptoms among children and adolescents with ASD. Journal of Autism and Developmental Disorders, 40(12), 1512–1520.PubMedCrossRef
go back to reference McDougle, C. J., Scahill, L., Aman, M. G., McCracken, J. T., Tierney, E., Davies, M., et al. (2005). Risperidone for the core symptom domains of autism: results from the study by the autism network of the research units on pediatric psychopharmacology. The American journal of psychiatry, 162(6), 1142–1148.PubMedCrossRef McDougle, C. J., Scahill, L., Aman, M. G., McCracken, J. T., Tierney, E., Davies, M., et al. (2005). Risperidone for the core symptom domains of autism: results from the study by the autism network of the research units on pediatric psychopharmacology. The American journal of psychiatry, 162(6), 1142–1148.PubMedCrossRef
go back to reference Mullen, E. (1995). Mullen scales of early learning. Circle Pines, MN: American Guidance Service. Mullen, E. (1995). Mullen scales of early learning. Circle Pines, MN: American Guidance Service.
go back to reference Pine, D. S., Guyer, A. E., Goldwin, M., Towbin, K. A., & Leibenluft, E. (2008). Autism spectrum disorder scale scores in pediatric mood and anxiety disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 47(6), 652–661.PubMedCrossRef Pine, D. S., Guyer, A. E., Goldwin, M., Towbin, K. A., & Leibenluft, E. (2008). Autism spectrum disorder scale scores in pediatric mood and anxiety disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 47(6), 652–661.PubMedCrossRef
go back to reference Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. (2002). Risperidone in children with autism and serious behavioral problems. New England Journal of Medicine, 347(5), 314–321.CrossRef Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. (2002). Risperidone in children with autism and serious behavioral problems. New England Journal of Medicine, 347(5), 314–321.CrossRef
go back to reference Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. (2005). Randomized, controlled, crossover trial of methylphenidate in pervasive developmental disorders with hyperactivity. Archives of General Psychiatry, 62(11), 1266–1274.CrossRef Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. (2005). Randomized, controlled, crossover trial of methylphenidate in pervasive developmental disorders with hyperactivity. Archives of General Psychiatry, 62(11), 1266–1274.CrossRef
go back to reference Roid, G. H., & Miller, L. J. (1997). Leiter international performance scale-revised. Wood Dale, IL: Stoelting. Roid, G. H., & Miller, L. J. (1997). Leiter international performance scale-revised. Wood Dale, IL: Stoelting.
go back to reference Scahill, L., McCracken, J. T., Bearss, K., Robinson, F., Hollander, E., King, B., et al. (2012). Design and subject characteristics in the federally-funded citalopram trial in children with pervasive developmental disorders. Journal of Autism and Developmental Disorders, 42(3), 432–440.PubMedCrossRef Scahill, L., McCracken, J. T., Bearss, K., Robinson, F., Hollander, E., King, B., et al. (2012). Design and subject characteristics in the federally-funded citalopram trial in children with pervasive developmental disorders. Journal of Autism and Developmental Disorders, 42(3), 432–440.PubMedCrossRef
go back to reference Scahill, L., McDougle, C. J., Williams, S. K., Dimitropoulos, A., Aman, M. G., McCracken, J. T., et al. (2006). Children’s yale-brown obsessive compulsive scale modified for pervasive developmental disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 45(9), 1114–1123.PubMedCrossRef Scahill, L., McDougle, C. J., Williams, S. K., Dimitropoulos, A., Aman, M. G., McCracken, J. T., et al. (2006). Children’s yale-brown obsessive compulsive scale modified for pervasive developmental disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 45(9), 1114–1123.PubMedCrossRef
go back to reference Scahill, L., Riddle, M. A., McSwiggin-Hardin, M., Ort, S. I., King, R. A., Goodman, W. K., et al. (1997). Children’s yale-brown obsessive compulsive scale: Reliability and validity. Journal of the American Academy of Child and Adolescent Psychiatry, 36(6), 844–852.PubMedCrossRef Scahill, L., Riddle, M. A., McSwiggin-Hardin, M., Ort, S. I., King, R. A., Goodman, W. K., et al. (1997). Children’s yale-brown obsessive compulsive scale: Reliability and validity. Journal of the American Academy of Child and Adolescent Psychiatry, 36(6), 844–852.PubMedCrossRef
go back to reference Sparrow, S. S., Balla, D. A., & Cicchetti, D. V. (1984). Vineland adaptive behavior scales. Circle Pines, MN: American Guidance Service. Sparrow, S. S., Balla, D. A., & Cicchetti, D. V. (1984). Vineland adaptive behavior scales. Circle Pines, MN: American Guidance Service.
go back to reference Sprafkin, J., Gadow, K. D., Salisbury, H., Schneider, J., & Loney, J. (2002). Further evidence of reliability and validity of the Child Symptom Inventory-4: Parent checklist in clinically referred boys. Journal of Clinical Child and Adolescent Psychology, 31(4), 513–524.PubMed Sprafkin, J., Gadow, K. D., Salisbury, H., Schneider, J., & Loney, J. (2002). Further evidence of reliability and validity of the Child Symptom Inventory-4: Parent checklist in clinically referred boys. Journal of Clinical Child and Adolescent Psychology, 31(4), 513–524.PubMed
go back to reference Sukhodolsky, D. G., Scahill, L., Gadow, K. D., Arnold, L. E., Aman, M. G., McDougle, C. J., et al. (2008). Parent-rated anxiety symptoms in children with pervasive developmental disorders: Frequency and association with core autism symptoms and cognitive functioning. Journal of Abnormal Child Psychology, 36(1), 117–128.PubMedCrossRef Sukhodolsky, D. G., Scahill, L., Gadow, K. D., Arnold, L. E., Aman, M. G., McDougle, C. J., et al. (2008). Parent-rated anxiety symptoms in children with pervasive developmental disorders: Frequency and association with core autism symptoms and cognitive functioning. Journal of Abnormal Child Psychology, 36(1), 117–128.PubMedCrossRef
go back to reference van Steensel, F. J., Bogels, S. M., & Perrin, S. (2011). Anxiety disorders in children and adolescents with autistic spectrum disorders: A meta-analysis. Clinical child and family psychology review. 14(3), 302–317. van Steensel, F. J., Bogels, S. M., & Perrin, S. (2011). Anxiety disorders in children and adolescents with autistic spectrum disorders: A meta-analysis. Clinical child and family psychology review. 14(3), 302–317.
go back to reference Wechsler, D. (1989). Wechsler preschool and primary scale of intelligence-revised. San Antonio, TX: The Psychological Corporation. Wechsler, D. (1989). Wechsler preschool and primary scale of intelligence-revised. San Antonio, TX: The Psychological Corporation.
go back to reference Wechsler, D. (1991). Wechsler intelligence scale for children (3rd ed.). San Antonio, TX: The Psychological Corporation. Wechsler, D. (1991). Wechsler intelligence scale for children (3rd ed.). San Antonio, TX: The Psychological Corporation.
go back to reference Weisbrot, D. M., Gadow, K. D., DeVincent, C. J., & Pomeroy, J. (2005). The presentation of anxiety in children with pervasive developmental disorders. Journal of Child and Adolescent Psychopharmacology, 15(3), 477–496.PubMedCrossRef Weisbrot, D. M., Gadow, K. D., DeVincent, C. J., & Pomeroy, J. (2005). The presentation of anxiety in children with pervasive developmental disorders. Journal of Child and Adolescent Psychopharmacology, 15(3), 477–496.PubMedCrossRef
go back to reference White, S. W., Oswald, D., Ollendick, T., & Scahill, L. (2009). Anxiety in children and adolescents with autism spectrum disorders. Clinical Psychology Review, 29(3), 216–229.PubMedCrossRef White, S. W., Oswald, D., Ollendick, T., & Scahill, L. (2009). Anxiety in children and adolescents with autism spectrum disorders. Clinical Psychology Review, 29(3), 216–229.PubMedCrossRef
go back to reference Witwer, A. N., & Lecavalier, L. (2010). Validity of comorbid psychiatric disorders in youngsters with autism spectrum disorders. Journal of Developmental and Physical Disabilities, 22(4), 367–380.CrossRef Witwer, A. N., & Lecavalier, L. (2010). Validity of comorbid psychiatric disorders in youngsters with autism spectrum disorders. Journal of Developmental and Physical Disabilities, 22(4), 367–380.CrossRef
Metagegevens
Titel
Exploring the Manifestations of Anxiety in Children with Autism Spectrum Disorders
Auteurs
Victoria Hallett
Luc Lecavalier
Denis G. Sukhodolsky
Noreen Cipriano
Michael G. Aman
James T. McCracken
Christopher J. McDougle
Elaine Tierney
Bryan H. King
Eric Hollander
Linmarie Sikich
Joel Bregman
Evdokia Anagnostou
Craig Donnelly
Lily Katsovich
Kimberly Dukes
Benedetto Vitiello
Kenneth Gadow
Lawrence Scahill
Publicatiedatum
01-10-2013
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 10/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-013-1775-1

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