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Spatial working memory (SWM) is known to be impaired in children with ADHD-CT, whether anxiety is present or not. Yet, it remains unclear whether anxiety disorders add to the SWM impairments evident in ADHD-CT and whether these findings extend into adolescents with ADHD-CT and anxiety. Further, it is not yet known whether children and adolescents with carefully defined anxiety disorders alone, demonstrate SWM deficits. This study explored the association of SWM and its strategy and spatial span components in carefully defined children and adolescents (age 6–16 years) with ADHD-CT alone (N = 163; 14 % female), ADHD-CT and anxiety (N = 243; 23 % female), anxiety disorders alone (N = 69; 25 % female) compared to age- and gender-matched healthy control participants (N = 116; 19 % female). The relationship between SWM and its strategy and span components and core ADHD-CT symptoms and anxiety symptoms were also examined. There was no evidence of an additive effect of ADHD and anxiety on SWM, strategy and spatial span deficits. But, anxiety disorders alone were associated with impaired SWM and span performance compared to healthy control participants. In contrast, strategy did not differ between children and adolescents with anxiety disorders alone and healthy control participants, suggesting that with anxiety span is the most affected component. Further, these findings were age-independent. This study concurs with and extends current influential models about the cognitive effects of anxiety on performance in the setting of ADHD-CT. Clinical implications and future research directions are discussed.
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Achenbach, T. M. (1991). Manual for the child behavior checklist / 4–18 and 1991 profile. Burlington: University of Vermont, Department of Psychiatry.
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders. (4th ed., Text Revision). Washington, DC: American Psychiatric Association.
Awh, E., & Jonides, J. (2001). Overlapping mechanisms of attention and spatial working memory. Trends in Cognitive Science, 5, 119–126. CrossRef
Baddeley, A. D. (1986). Working memory. Oxford: Clarendon.
Castellanos, F. X., & Tannock, R. (2002). Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes. Nature Reviews Neuroscience, 3, 617–628. PubMed
Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Mahwah: Lawrence Erlbaum.
Conners, C. K., Wells, K. C., Parker, J. D., Sitarenios, G., Diamond, J. M., & Powell, J. W. (1997). A new self-report scale for assessment of adolescent psychopathology: factor structure, reliability, validity, and diagnostic sensitivity. Journal of Abnormal Child Psychology, 25, 487–497. PubMedCrossRef
Dennis, M., Francis, D. J., Cirino, P. T., Schachar, R., Barnes, M. A., & Fletcher, J. M. (2009). Why IQ is not a covariate in cognitive studies of neurodevelopmental disorders. Journal of International Neuropsychological Society, 15, 331–343. CrossRef
Fray, P. J., Robbins, T. W., & Sahakian, B. J. (1996). Neuropsychiatric applications of CANTAB. International Journal of Geriatric Psychiatry, 11, 329–336. CrossRef
Goldman-Rakic, P. S. (1987). Circuitry of the primate prefrontal cortex and regulation of behaviour by representational memory. In F. Plum (Ed.), Handbook of physiology, the nervous system, higher functions of the brain (Vol. V, pp. 373–417). Maryland: American Physiological Society.
Goldman-Rakic, P. S. (1995). Architecture of the prefrontal cortex and the central executive. In J. Grafman, K. J. Holoyoak, & F. Boller (Eds.), The structure and function of the prefrontal cortex (Annals of the New York Academy of Sciences, Vol. 769, pp. 71–83). New York: New York Academy of Sciences.
Kaufman, J., Birmaher, B., Brent, D. A., Ryan, N. D., & Rao, U. (2000). Schedule for affective disorders and schizophrenia for school-age children—present and lifetime version (K-SADS-PL). The K-SADS-PL. Journal of the American Academy of Child and Adolescent Psychiatry, 39, 49–58. CrossRef
Koric, L., Volle, E., Seassau, M., Bernard, .FA,, Mancini, J., & Dubois, B. (2011) How cognitive performance-induced stess can influence right VLPFC activation: an fMRI study with healthy subjects and patients with social phobia. Human Brain Mapping (in press).
Lavric, A., Rippon, G., & Gray, J. R. (2003). Threat-evoked anxiety disrupts spatial working memory performance: an attentional account. Cognitive Therapy and Research, 27, 489–504. CrossRef
Manassis, K., Tannock, R., Young, A., & Francis-John, S. (2007). Cognition in anxious children with ADHD: a comparison of clinical and normal children. Behavioral and Brain Functions, 15, 3–4.
Merikangas, K. R., He, J. P., Burstein, M., Swendsen, J., Avenevoli, S., & Case, B. (2011). Service utilization for lifetime mental disorders in US adolescents: results of the National Comorbidity Study—Adolescent Supplement (NCS-A). Journal of the American Academy of Child and Adolescent Psychiatry, 50, 32–45. PubMedCrossRef
Nigg, J. T. (2000). On inhibition/disinhibition in developmental psychopathology: views from cognitive and personality psychology and a working inhibition taxonomy. Psychological Bulletin, 126, 240–266. CrossRef
Reynolds, C. R., & Richmond, B. O. (1985). Revised children’s manifest anxiety scale. Los Angeles: Western Psychological Services.
Robbins, T. W., James, M., Owen, A. M., Sahakian, B. J., McInnes, L., & Rabbitt, P. (1994). Cambridge Neuropsychological Test Automated Battery (CANTAB): a factor analytic study of a large sample of normal elderly volunteers. Dementia, 5, 266–281. PubMed
Sahakian, B. J., & Owen, A. M. (1992). Computerised assessment in neuropsychiatry using CANTAB: discussion paper. Journal of the Royal Society of Medicine, 85, 399–402. PubMed
Tannock, R. (2009). ADHD with anxiety disorders. In T. E. Brown (Ed.), ADHD comorbidities: Handbook for ADHD complications in children and adults (pp. 131–156). Washington DC: American Psychiatric Association.
Vance, A., Barnett, R., Costin, J., Luk, S. L., Maruff, P., & Tonge, B. J. (2002). Characteristics of parent- and child-reported anxiety in psychostimulant medication naïve, clinically referred children with attention deficit hyperactivity disorder, combined type (ADHD-CT). The Australian and New Zealand Journal of Psychiatry, 36, 234–239. PubMedCrossRef
Vance, A. (2011). Differential diagnosis and comorbid ADHD in childhood anxiety. In E. Storch & D. McKay (Eds.), Handbook of child and adolescent anxiety disorders (pp. 121–134). New York: Springer. CrossRef
Wechsler, D. (1991). Wechsler intelligence scale for children (3rd ed.). Texas: The Psychological Corporation.
Wilkinson, G. S. (1993). Wide range achievement test 3 (WRAT-3). Delaware: Wilmington.
- Examination of Spatial Working Memory Performance in Children and Adolescents with Attention Deficit Hyperactivity Disorder, Combined Type (ADHD-CT) and Anxiety
- Springer US