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01-02-2011 | Original Paper | Uitgave 2/2011

Evaluation of a Records-Review Surveillance System Used to Determine the Prevalence of Autism Spectrum Disorders

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 2/2011

Auteurs:: Rachel Nonkin Avchen, Lisa D. Wiggins, Owen Devine, Kim Van Naarden Braun, Catherine Rice, Nancy C. Hobson, Diana Schendel, Marshalyn Yeargin-Allsopp

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Abstract

We conducted the first study that estimates the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of a population-based autism spectrum disorders (ASD) surveillance system developed at the Centers for Disease Control and Prevention. The system employs a records-review methodology that yields ASD classification (case versus non-ASD case) and was compared with classification based on clinical examination. The study enrolled 177 children. Estimated specificity (0.96, [CI_.95 = 0.94, 0.99]), PPV (0.79 [CI_.95 = 0.66, 0.93]), and NPV (0.91 [CI_.95 = 0.87, 0.96]) were high. Sensitivity was lower (0.60 [CI_.95 = 0.45, 0.75]). Given diagnostic heterogeneity, and the broad array of ASD in the population, identifying children with ASD is challenging. Records-based surveillance yields a population-based estimate of ASD that is likely conservative.

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Titel: Evaluation of a Records-Review Surveillance System Used to Determine the Prevalence of Autism Spectrum Disorders
Auteurs:: Rachel Nonkin Avchen
Lisa D. Wiggins
Owen Devine
Kim Van Naarden Braun
Catherine Rice
Nancy C. Hobson
Diana Schendel
Marshalyn Yeargin-Allsopp
Publicatiedatum: 01-02-2011
DOI: https://doi.org/10.1007/s10803-010-1050-7
Uitgeverij: Springer US
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 2/2011
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

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