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Gepubliceerd in: Journal of Autism and Developmental Disorders 2/2011

01-02-2011 | Original Paper

Evaluation of a Records-Review Surveillance System Used to Determine the Prevalence of Autism Spectrum Disorders

Auteurs: Rachel Nonkin Avchen, Lisa D. Wiggins, Owen Devine, Kim Van Naarden Braun, Catherine Rice, Nancy C. Hobson, Diana Schendel, Marshalyn Yeargin-Allsopp

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 2/2011

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Abstract

We conducted the first study that estimates the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of a population-based autism spectrum disorders (ASD) surveillance system developed at the Centers for Disease Control and Prevention. The system employs a records-review methodology that yields ASD classification (case versus non-ASD case) and was compared with classification based on clinical examination. The study enrolled 177 children. Estimated specificity (0.96, [CI.95 = 0.94, 0.99]), PPV (0.79 [CI.95 = 0.66, 0.93]), and NPV (0.91 [CI.95 = 0.87, 0.96]) were high. Sensitivity was lower (0.60 [CI.95 = 0.45, 0.75]). Given diagnostic heterogeneity, and the broad array of ASD in the population, identifying children with ASD is challenging. Records-based surveillance yields a population-based estimate of ASD that is likely conservative.
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Metagegevens
Titel
Evaluation of a Records-Review Surveillance System Used to Determine the Prevalence of Autism Spectrum Disorders
Auteurs
Rachel Nonkin Avchen
Lisa D. Wiggins
Owen Devine
Kim Van Naarden Braun
Catherine Rice
Nancy C. Hobson
Diana Schendel
Marshalyn Yeargin-Allsopp
Publicatiedatum
01-02-2011
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 2/2011
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-010-1050-7

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