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Gepubliceerd in: Quality of Life Research 5/2023

09-01-2023

Evaluating health-related quality of life and subjective wellbeing among infertility patients: a cross-sectional study in mainland China

Auteurs: Zhao Shi, Hongwei Nie, Ling Geng, Xuewen Wang, Gang Chen, Shunping Li

Gepubliceerd in: Quality of Life Research | Uitgave 5/2023

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Abstract

Purpose

This study aimed to explore the health-related quality of life (HRQoL) and subjective wellbeing (SWB) of infertility patients in mainland China and to investigate the relationships between HRQoL and SWB instruments in infertility patients.

Methods

We conducted this cross-sectional study in the Hospital for Reproductive Medicine Affiliated of Shandong University between April 2019 and November 2019. Participants self-completed the five-level EQ-5D (EQ-5D-5L) questionnaire, the Assessment of Quality of Life (AQoL)-8D, and the WHO-5 wellbeing index (WHO-5). The agreements between EQ-5D-5L and AQoL-8D were assessed employing intraclass correlation coefficient (ICC) and Bland-Altman plots. Exploratory factor analysis (EFA) was conducted to examine the difference in descriptive systems among the three instruments.

Results

We analyzed a valid sample of 618 infertility patients (84.4%). The mean scores of the total EQ-5D-5L, AQoL-8D, and WHO-5 were 0.96 (95%CI 0.96, 0.96), 0.80 (95%CI 0.79, 0.81), and 16.92 (95%CI 16.52, 17.31), respectively. Patients diagnosed with primary infertility had significantly lower HRQoL and SWB than those with secondary infertility. The ICC of EQ-5D-5L and AQoL-8D was 0.14. The AQoL-8D (r = 0.625) was more strongly correlated with WHO-5 than with the EQ-5D-5L (r = 0.262). The EFA results indicated that HRQoL instruments and the WHO-5 instruments were complementary rather than substitutable.

Conclusions

Poorer HRQoL and SWB were found that primary than secondary infertility patients. There exists a poor agreement between EQ-5D-5L and AQoL-8D and the difference in the psychosocial components may explain the difference. Measuring both HRQoL and SWB could provide complementary information for infertility patients.
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Literatuur
11.
13.
go back to reference Brazier, J., Ratcliffe, J., Salomon, J., & Tsuchiya, A. (2017). Measuring and valuing health benefits for economic evaluation (2nd ed.). Oxford University Press. Brazier, J., Ratcliffe, J., Salomon, J., & Tsuchiya, A. (2017). Measuring and valuing health benefits for economic evaluation (2nd ed.). Oxford University Press.
15.
go back to reference Mousavi, S. A., Masoumi, S. Z., Keramat, A., Pooralajal, J., & Shobeiri, F. (2013). Assessment of questionnaires measuring quality of life in infertile couples: A systematic review. Journal of Reproduction & Infertility, 14(3), 110–119. Mousavi, S. A., Masoumi, S. Z., Keramat, A., Pooralajal, J., & Shobeiri, F. (2013). Assessment of questionnaires measuring quality of life in infertile couples: A systematic review. Journal of Reproduction & Infertility, 14(3), 110–119.
27.
go back to reference Walters, S. (2009). Quality of life outcomes in clinical trials and health-care evaluation. New York: Wiley.CrossRef Walters, S. (2009). Quality of life outcomes in clinical trials and health-care evaluation. New York: Wiley.CrossRef
36.
go back to reference Richardson, J., Mckie, J., & Bariola, E. (2014). Multiattribute utility instruments and their use. Encyclopedia of Health Economics, 2, 341–357. Richardson, J., Mckie, J., & Bariola, E. (2014). Multiattribute utility instruments and their use. Encyclopedia of Health Economics, 2, 341–357.
37.
go back to reference Si, L., Tu, L., Xie, Y., Chen, G., Hiligsmann, M., Yang, M., et al. (2020). Evaluating health related quality of life in older people at risk of osteoporotic fracture: A head-to-head comparison of the EQ-5D-5L and AQoL-6D. Social Indicators Research, 160(2–3), 809–824. https://doi.org/10.1007/s11205-020-02414-8CrossRef Si, L., Tu, L., Xie, Y., Chen, G., Hiligsmann, M., Yang, M., et al. (2020). Evaluating health related quality of life in older people at risk of osteoporotic fracture: A head-to-head comparison of the EQ-5D-5L and AQoL-6D. Social Indicators Research, 160(2–3), 809–824. https://​doi.​org/​10.​1007/​s11205-020-02414-8CrossRef
40.
go back to reference WHO. (1998). Wellbeing measures in primary health care/The Depcare Project. WHO Regional Office for Europe. WHO. (1998). Wellbeing measures in primary health care/The Depcare Project. WHO Regional Office for Europe.
45.
go back to reference Fayers, P., & Machin, D. (2016). Quality of life: The assessment, analysis and interpretation of patient-reported outcomes. Wiley Blackwell. Fayers, P., & Machin, D. (2016). Quality of life: The assessment, analysis and interpretation of patient-reported outcomes. Wiley Blackwell.
47.
go back to reference Ratner, B. (2009). The correlation coefficient: Its values range between +1/1, or do they? Journal of Targeting Measurement & Analysis for Marketing, 17(2), 139–142.CrossRef Ratner, B. (2009). The correlation coefficient: Its values range between +1/1, or do they? Journal of Targeting Measurement & Analysis for Marketing, 17(2), 139–142.CrossRef
67.
go back to reference Fu, B., Qin, N., Cheng, L., Tang, G. X., Cao, Y., Yan, C. L., et al. (2015). Development and validation of an Infertility Stigma Scale for Chinese women. Journal of Psychosomatic Research, 79(1), 69–75.CrossRefPubMed Fu, B., Qin, N., Cheng, L., Tang, G. X., Cao, Y., Yan, C. L., et al. (2015). Development and validation of an Infertility Stigma Scale for Chinese women. Journal of Psychosomatic Research, 79(1), 69–75.CrossRefPubMed
68.
go back to reference Liu, Y., Luo, J., & Tan, H. (2015). Happiness of infertile patients and its related influence factors (in chinese). China Journal of Modern Medicine, 25(21), 92–95. Liu, Y., Luo, J., & Tan, H. (2015). Happiness of infertile patients and its related influence factors (in chinese). China Journal of Modern Medicine, 25(21), 92–95.
Metagegevens
Titel
Evaluating health-related quality of life and subjective wellbeing among infertility patients: a cross-sectional study in mainland China
Auteurs
Zhao Shi
Hongwei Nie
Ling Geng
Xuewen Wang
Gang Chen
Shunping Li
Publicatiedatum
09-01-2023
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 5/2023
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-022-03330-9

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