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01-03-2009 | Brief Communication

Estimating health utilities in patients with asthma and COPD: evidence on the performance of EQ-5D and SF-6D

Auteurs: A. Szende, N. K. Leidy, E. Ståhl, K. Svensson

Gepubliceerd in: Quality of Life Research | Uitgave 2/2009

Abstract

Objective

The objective of this study was to understand systematic differences in utility values derived from the EQ-5D and the SF-6D in two respiratory populations with heterogeneous disease severity.

Methods

This study involved secondary analysis of data from two cross-sectional surveys of patients with asthma (N = 228; Hungary) and COPD (N = 176; Sweden). Disease severity was defined according to GINA and GOLD guidelines for asthma and COPD, respectively. EQ-5D and SF-6D scores and their distributional characteristics were compared across the two samples by disease severity level.

Results

Within each patient population, mean EQ-5D and SF-6D scores were similar for the overall group and for those with moderate disease. Mean scores varied for patients with mild and severe disease. EQ-5D versus SF-6D scores in the asthma group by severity levels were 0.89 versus 0.80, 0.70 versus 0.73, 0.63 versus 0.64, and 0.51 versus 0.63, respectively. EQ-5D versus SF-6D scores in the COPD group by severity levels were 0.85 versus 0.80, 0.73 versus 0.73, 0.74 versus 0.73, and 0.53 versus 0.62, respectively.

Conclusions

Results suggest the EQ-5D and SF-6D do not yield consistent utility values in patients with asthma and COPD due to differences in underlying valuation techniques and the EQ-5D’s limited response options relative to mild disease.

vorige artikel The first stage of developing preference-based measures: constructing a health-state classification using Rasch analysis

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Titel: Estimating health utilities in patients with asthma and COPD: evidence on the performance of EQ-5D and SF-6D
Auteurs: A. Szende
N. K. Leidy
E. Ståhl
K. Svensson
Publicatiedatum: 01-03-2009
Uitgeverij: Springer Netherlands
Gepubliceerd in: Quality of Life Research / Uitgave 2/2009
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-008-9429-z

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