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Gepubliceerd in: Journal of Autism and Developmental Disorders 6/2013

01-06-2013 | Original Paper

Epilepsy in Individuals with a History of Asperger’s Syndrome: A Danish Nationwide Register-Based Cohort Study

Auteurs: Svend Erik Mouridsen, Bente Rich, Torben Isager

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 6/2013

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Abstract

We performed a nationwide, register-based retrospective follow-up study of epilepsy in all people who were born between January 1, 1980 and June 29, 2006 and registered in the Danish Psychiatric Central Register with Asperger’s syndrome on February 7, 2011. All 4,180 identified cases with AS (3,431 males and 749 females) were screened through the nationwide Danish National Hospital Register (DNHR) with respect to epilepsy. Mean age at follow-up was 18.1 years (range 4–31 years). Of the 4,180 individuals with AS, 164 (3.9 %) were registered with at least one epilepsy diagnosis in the DNHR, which is significantly increased (p < 0.0001) relative to the same age group in the general population, where an estimate is about 2.0 %.
Literatuur
go back to reference American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: American Psychiatric Association. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: American Psychiatric Association.
go back to reference Amiet, C., Gourfinkel-An, I., Bouzamondo, A., Tordjman, S., Baulac, M., Lechat, P., et al. (2008). Epilepsy in autism is associated with intellectual disability and gender: Evidence from a meta-analysis. Biological Psychiatry, 64, 577–582.PubMedCrossRef Amiet, C., Gourfinkel-An, I., Bouzamondo, A., Tordjman, S., Baulac, M., Lechat, P., et al. (2008). Epilepsy in autism is associated with intellectual disability and gender: Evidence from a meta-analysis. Biological Psychiatry, 64, 577–582.PubMedCrossRef
go back to reference Analytical Software. (2006). STATISTIX. Tallahassee, FL: Analytical Software. Analytical Software. (2006). STATISTIX. Tallahassee, FL: Analytical Software.
go back to reference Andersen, T. F., Madsen, M., Jørgensen, J., Mellemkjoer, L., & Olsen, J. H. (1999). The Danish National Hospital Register. A valuable source of data for modern health sciences. Danish Medical Bulletin, 46, 263–268.PubMed Andersen, T. F., Madsen, M., Jørgensen, J., Mellemkjoer, L., & Olsen, J. H. (1999). The Danish National Hospital Register. A valuable source of data for modern health sciences. Danish Medical Bulletin, 46, 263–268.PubMed
go back to reference Asperger, H. (1944). Autistic psychopathy in childhood: In U. Frith (Ed). Autism and Asperger’s Syndrome (pp. 37–92). Cambridge: Cambridge University Press; 1991. Asperger, H. (1944). Autistic psychopathy in childhood: In U. Frith (Ed). Autism and Asperger’s Syndrome (pp. 37–92). Cambridge: Cambridge University Press; 1991.
go back to reference Bauman, M. L. (2010). Medical comorbidities in autism: Challenge to diagnosis and treatment. Neurotherapeutics, 7, 320–327.PubMedCrossRef Bauman, M. L. (2010). Medical comorbidities in autism: Challenge to diagnosis and treatment. Neurotherapeutics, 7, 320–327.PubMedCrossRef
go back to reference Berg, A. T., & Plioplys, S. (2012). Epilepsy and autism: Is there a special relationship? Epilepsy & Behavior, 23, 193–198.CrossRef Berg, A. T., & Plioplys, S. (2012). Epilepsy and autism: Is there a special relationship? Epilepsy & Behavior, 23, 193–198.CrossRef
go back to reference Canitano, R. (2007). Epilepsy in autism spectrum disorders. European Child and Adolescent Psychiatry, 16, 61–66.PubMedCrossRef Canitano, R. (2007). Epilepsy in autism spectrum disorders. European Child and Adolescent Psychiatry, 16, 61–66.PubMedCrossRef
go back to reference Cederlund, M., & Gillberg, C. (2004). One hundred males with Asperger syndrome: A clinical study of background and associated factors. Developmental Medicine and Child Neurology, 46, 652–660.PubMedCrossRef Cederlund, M., & Gillberg, C. (2004). One hundred males with Asperger syndrome: A clinical study of background and associated factors. Developmental Medicine and Child Neurology, 46, 652–660.PubMedCrossRef
go back to reference Christensen, J., Vestergaard, M., Olsen, J., & Sidenius, P. (2007a). Validation of epilepsy diagnoses in the Danish National Hospital Register. Epilepsy Research, 75, 162–170.PubMedCrossRef Christensen, J., Vestergaard, M., Olsen, J., & Sidenius, P. (2007a). Validation of epilepsy diagnoses in the Danish National Hospital Register. Epilepsy Research, 75, 162–170.PubMedCrossRef
go back to reference Christensen, J., Vestergaard, M., Pedersen, M. G., Pedersen, C. B., Olsen, J., & Sidenius, P. (2007b). Incidence and prevalence of epilepsy in Denmark. Epilepsy Research, 76, 60–65.PubMedCrossRef Christensen, J., Vestergaard, M., Pedersen, M. G., Pedersen, C. B., Olsen, J., & Sidenius, P. (2007b). Incidence and prevalence of epilepsy in Denmark. Epilepsy Research, 76, 60–65.PubMedCrossRef
go back to reference Commission on Classification and Terminology of the International League Against Epilepsy. (1981). Proposal for revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia, 22, 489–501.CrossRef Commission on Classification and Terminology of the International League Against Epilepsy. (1981). Proposal for revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia, 22, 489–501.CrossRef
go back to reference Lauritsen, M. B., Jørgensen, M., Madsen, K. M., et al. (2010). Validity of childhood autism in the Danish Psychiatric Central Register: Findings from a cohort sample born 1990–1999. Journal of Autism and Developmental Disorders, 40, 139–148.PubMedCrossRef Lauritsen, M. B., Jørgensen, M., Madsen, K. M., et al. (2010). Validity of childhood autism in the Danish Psychiatric Central Register: Findings from a cohort sample born 1990–1999. Journal of Autism and Developmental Disorders, 40, 139–148.PubMedCrossRef
go back to reference Mors, O., Perto, G. P., & Mortensen, P. B. (2011). The Danish Psychiatric Central Research Register. Scandinavian Journal of Public Health, 39(Suppl 7), 54–57.PubMedCrossRef Mors, O., Perto, G. P., & Mortensen, P. B. (2011). The Danish Psychiatric Central Research Register. Scandinavian Journal of Public Health, 39(Suppl 7), 54–57.PubMedCrossRef
go back to reference Mouridsen, S. E., Brønnum-Hansen, H., Rich, B., & Isager, T. (2008). Mortality and causes of death in autism spectrum disorders: An update. Autism, 12, 403–414.PubMedCrossRef Mouridsen, S. E., Brønnum-Hansen, H., Rich, B., & Isager, T. (2008). Mortality and causes of death in autism spectrum disorders: An update. Autism, 12, 403–414.PubMedCrossRef
go back to reference Mouridsen, S. E., Rich, B., & Isager, T. (1999). Epilepsy in disintegrative psychosis and infantile autism: A long-term validation study. Developmental Medicine and Child Neurology, 41, 110–114.PubMedCrossRef Mouridsen, S. E., Rich, B., & Isager, T. (1999). Epilepsy in disintegrative psychosis and infantile autism: A long-term validation study. Developmental Medicine and Child Neurology, 41, 110–114.PubMedCrossRef
go back to reference Mouridsen, S. E., Rich, B., & Isager, T. (2011a). A longitudinal study of epilepsy and other central nervous system disease in individuals with and without a history of infantile autism. Brain and Development, 33, 361–366.PubMedCrossRef Mouridsen, S. E., Rich, B., & Isager, T. (2011a). A longitudinal study of epilepsy and other central nervous system disease in individuals with and without a history of infantile autism. Brain and Development, 33, 361–366.PubMedCrossRef
go back to reference Mouridsen, S. E., Rich, B., & Isager, T. (2011b). Epilepsy and other central nervous system diseases in atypical autism: A case control study. Journal of Neural Transmission, 118, 621–627.PubMedCrossRef Mouridsen, S. E., Rich, B., & Isager, T. (2011b). Epilepsy and other central nervous system diseases in atypical autism: A case control study. Journal of Neural Transmission, 118, 621–627.PubMedCrossRef
go back to reference Peake, D., Notghi, L. M., & Philip, S. (2006). Management of epilepsy in children with autism. Current Paediatrics, 16, 489–494.CrossRef Peake, D., Notghi, L. M., & Philip, S. (2006). Management of epilepsy in children with autism. Current Paediatrics, 16, 489–494.CrossRef
go back to reference Pedersen, C. B., Gøtzsche, H., Møller, J. Ø., & Mortensen, P. B. (2006). The Danish Civil Registration System. Danish Medical Bulletin, 53, 441–449.PubMed Pedersen, C. B., Gøtzsche, H., Møller, J. Ø., & Mortensen, P. B. (2006). The Danish Civil Registration System. Danish Medical Bulletin, 53, 441–449.PubMed
go back to reference Pickett, J., Xiu, E., Tuchman, R., Dawson, G., & Lajonchere, C. (2011). Mortality in individuals with autism, with and without epilepsy. Journal of Child Neurology, 8, 932–939.CrossRef Pickett, J., Xiu, E., Tuchman, R., Dawson, G., & Lajonchere, C. (2011). Mortality in individuals with autism, with and without epilepsy. Journal of Child Neurology, 8, 932–939.CrossRef
go back to reference Sørensen, H. T., Sabroe, S., & Olsen, J. (1996). A framework for evaluation of secondary data sources for epidemiological research. International Journal of Epidemiology, 25, 435–442.PubMedCrossRef Sørensen, H. T., Sabroe, S., & Olsen, J. (1996). A framework for evaluation of secondary data sources for epidemiological research. International Journal of Epidemiology, 25, 435–442.PubMedCrossRef
go back to reference Steffenburg, U., Hagberg, G., & Hagberg, B. (2001). Epilepsy in a representative series of Rett syndrome. Acta Paediatrica, 90, 34–39.PubMedCrossRef Steffenburg, U., Hagberg, G., & Hagberg, B. (2001). Epilepsy in a representative series of Rett syndrome. Acta Paediatrica, 90, 34–39.PubMedCrossRef
go back to reference Tuchman, R., Cuccaro, M., & Alessandri, M. (2010). Autism and epilepsy: Historical perspective. Brain and Development, 32, 709–718.PubMedCrossRef Tuchman, R., Cuccaro, M., & Alessandri, M. (2010). Autism and epilepsy: Historical perspective. Brain and Development, 32, 709–718.PubMedCrossRef
go back to reference World Health Organization. (1971). International classification of diseases, Danish version (8th ed.). Copenhagen: Sundhedsstyrelsen (National Board of Health). World Health Organization. (1971). International classification of diseases, Danish version (8th ed.). Copenhagen: Sundhedsstyrelsen (National Board of Health).
go back to reference World Health Organization. (1992). The ICD-10 classification of mental and behavioural disorders. Clinical descriptions and diagnostic guidelines. Geneva: World Health Organization. World Health Organization. (1992). The ICD-10 classification of mental and behavioural disorders. Clinical descriptions and diagnostic guidelines. Geneva: World Health Organization.
Metagegevens
Titel
Epilepsy in Individuals with a History of Asperger’s Syndrome: A Danish Nationwide Register-Based Cohort Study
Auteurs
Svend Erik Mouridsen
Bente Rich
Torben Isager
Publicatiedatum
01-06-2013
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 6/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-012-1675-9

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