Swipe om te navigeren naar een ander artikel
The present population-based study examines associations between epilepsy and autism spectrum disorders (ASD). The cohort includes register data of 4,705 children born between 1987 and 2005 and diagnosed as cases of childhood autism, Asperger’s syndrome or pervasive developmental disorders—not otherwise specified. Each case was matched to four controls by gender, date of birth, place of birth, and residence in Finland. Epilepsy was associated with ASD regardless of the subgroup after adjusting for covariates. The associations were stronger among cases with intellectual disability, especially among females. Epilepsy’s age at onset was similar between the cases and controls regardless of the ASD subgroup. These findings emphasize the importance to examine the neurodevelopmental pathways in ASD, epilepsy and intellectual disability.
Log in om toegang te krijgen
Met onderstaand(e) abonnement(en) heeft u direct toegang:
Bradley, E. A., Thompson, A., & Bryson, S. E. (2002). Mental retardation in teenagers: Prevalence data from the Niagara Region, Ontario. Canadian Journal of Psychiatry, 47, 652–659.
Daniels, J. L., Forssen, U., Hultman, C. M., Cnattingius, S., Savitz, D. A., Feychting, M., et al. (2008). Parental psychiatric disorders associated with autism spectrum disorders in the offspring. Pediatrics, 121, 1357–1362. CrossRef
Deykin, E. Y., & MacMahon, B. (1979). The incidence of seizures among children with autistic symptoms. The American Journal of Psychiatry, 136, 1310–1312. PubMed
Giovanardi-Rossi, P., Parmeggiani, A., Bach, V., Santucci, M., & Visconti, P. (1995). EEG features and epilepsy in patients with autism. Brain & Development, 17, 169–174. CrossRef
Giovanardi-Rossi, P., Posar, A., & Parmeggiani, A. (2000). Epilepsy in adolescents and young adults with autistic disorder. Brain & Development, 22, 102–106. CrossRef
Guilmatre, A., Dubourg, C., Mosca, A. L., Legallic, S., Goldenberg, A., Drouin-Garraud, V., et al. (2009). Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation. Archives of General Psychiatry, 66, 947–956. PubMedCrossRefPubMedCentral
Hara, H. (2007). Autism and epilepsy: A retrospective follow-up study. Brain & Development, 29, 486–490. CrossRef
Matsuo, M., Maeda, T., Sasaki, K., Ishii, K., & Hamasaki, Y. (2010). Frequent association of autism spectrum disorder in patients with childhood onset epilepsy. Brain & Development, 32, 759–763. CrossRef
McLaren, J., & Bryson, S. E. (1987). Review of recent epidemiological studies of mental retardation: Prevalence, associated disorders, and etiology. American Journal on Mental Retardation, 92, 243–254. PubMed
Mouridsen, S. E., Rich, B., & Isager, T. (2011a). A longitudinal study of epilepsy and other central nervous system diseases in individuals with and without a history of infantile autism. Brain & Development, 33, 361–366. CrossRef
Peake, D., Notghi, L. M., & Philip, S. (2006). Management of epilepsy in children with autism. Current Paediatrics, 16, 489–494. CrossRef
SAS Institute Inc. (2010). SAS Version 9.4. Cary, NC.
Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child and Adolescent Psychiatry, 47, 921–929. PubMedCrossRef
Tuchman, R., Cuccaro, M., & Alessandri, M. (2010). Autism and epilepsy: Historical perspective. Brain & Development, 32, 709–718. CrossRef
Tuchman, R., & Rapin, I. (2002). Epilepsy in autism. Lancet Neurology, 1, 352–358. CrossRef
Tuchman, R., Rapin, I., & Shinnar, S. (1991). Autistic and dysphasic children. II: Epilepsy. Pediatrics, 88, 1219–1225. PubMed
van Blarikom, W., Tan, I. Y., Aldenkamp, A. P., & van Gennep, A. T. (2006). Epilepsy, intellectual disability, and living environment: A critical review. Epilepsy & Behaviour, 9, 14–18. CrossRef
World Health Organization. (1967). International classification of diseases, eighth revision (ICD-8). Geneva: World Health Organization.
World Health Organization. (1977). International classification of diseases, ninth revision (ICD-9). Geneva: World Health Organization.
World Health Organization. (1992). International classification of diseases, tenth revision (ICD-10). Geneva: World Health Organization.
- Epilepsy Among Children and Adolescents with Autism Spectrum Disorders: A Population-Based Study
Alan S. Brown
- Springer US