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Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-01-2012 | Original paper

Enhanced Cortisol Response to Stress in Children in Autism

Auteurs: Eve G. Spratt, Joyce S. Nicholas, Kathleen T. Brady, Laura A. Carpenter, Charles R. Hatcher, Kirk A. Meekins, Richard W. Furlanetto, Jane M. Charles

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 1/2012

Abstract

Children with Autism often show difficulties in adapting to change. Previous studies of cortisol, a neurobiologic stress hormone reflecting hypothalamic–pituitary–adrenal (HPA) axis activity, in children with autism have demonstrated variable results. This study measured cortisol levels in children with and without Autism: (1) at rest; (2) in a novel environment; and (3) in response to a blood draw stressor. A significantly higher serum cortisol response was found in the group of children with autism. Analysis showed significantly higher peak cortisol levels and prolonged duration and recovery of cortisol elevation following the blood-stick stressor in children with autism. This study suggests increased reactivity of the HPA axis to stress and novel stimuli in children with autism.

vorige artikel A Meta-Analysis of Single Case Research Studies on Aided Augmentative and Alternative Communication Systems with Individuals with Autism Spectrum Disorders

volgende artikel New Autism Diagnostic Interview-Revised Algorithms for Toddlers and Young Preschoolers from 12 to 47 Months of Age

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Titel: Enhanced Cortisol Response to Stress in Children in Autism
Auteurs: Eve G. Spratt
Joyce S. Nicholas
Kathleen T. Brady
Laura A. Carpenter
Charles R. Hatcher
Kirk A. Meekins
Richard W. Furlanetto
Jane M. Charles
Publicatiedatum: 01-01-2012
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 1/2012
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-011-1214-0

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