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Gepubliceerd in: Journal of Autism and Developmental Disorders 5/2015

01-05-2015 | Original Paper

Emergence of Autism Spectrum Disorder in Children from Simplex Families: Relations to Parental Perceptions of Etiology

Auteurs: Robin P. Goin-Kochel, Sarah S. Mire, Allison G. Dempsey

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 5/2015

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Abstract

Current research describes a four-category scheme of Autism Spectrum Disorder (ASD) onset: early, regressive, plateau, delay + regression. To replicate prevalence of different onset types, ASD onset (per the Autism Diagnostic InterviewRevised) was examined in a large North American sample; for a subset, parents’ causal beliefs were ascertained via the Revised Illness Perception Questionnaire to examine potential associations with ASD-onset types. Onset rates were similar across samples, with a slightly higher proportion of children in the subsample categorized with regression. Top-rated causes of ASD were genetics, brain structure, will of God, toxins in vaccines, and environmental pollution. Parents reporting regression more often believed that toxins in vaccines caused ASD. Influences on treatment selection and broader public-health ramifications are discussed.
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Literatuur
go back to reference American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: American Psychiatric Association Text Revision, DSM-IV-TR. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: American Psychiatric Association Text Revision, DSM-IV-TR.
go back to reference Baird, G., Charman, T., Pickles, A., Chandler, S., Loucas, T., Meldrum, D., et al. (2008). Regression, developmental trajectory and associated problems in disorders in the autism spectrum: The SNAP study. Journal of Autism and Developmental Disorders, 38(10), 1827–1836. doi: 10.​1007/​s10803-008-0571-9. CrossRefPubMed Baird, G., Charman, T., Pickles, A., Chandler, S., Loucas, T., Meldrum, D., et al. (2008). Regression, developmental trajectory and associated problems in disorders in the autism spectrum: The SNAP study. Journal of Autism and Developmental Disorders, 38(10), 1827–1836. doi: 10.​1007/​s10803-008-0571-9. CrossRefPubMed
go back to reference Baxter, A. J., & Krenzelok, E. P. (2008). Pediatric fatality secondary to EDTA chelation. Clinical Toxicology (Philadelphia, PA), 46(10), 1083–1084. CrossRef Baxter, A. J., & Krenzelok, E. P. (2008). Pediatric fatality secondary to EDTA chelation. Clinical Toxicology (Philadelphia, PA), 46(10), 1083–1084. CrossRef
go back to reference Bazzano, A., Zeldin, A., Schuster, E., Barrett, C., & Lehrer, D. (2012). Vaccine-related beliefs and practices of parents of children with autism spectrum disorders. American Journal of Intellectual and Developmental Disabilities, 117(3), 233–242. Bazzano, A., Zeldin, A., Schuster, E., Barrett, C., & Lehrer, D. (2012). Vaccine-related beliefs and practices of parents of children with autism spectrum disorders. American Journal of Intellectual and Developmental Disabilities, 117(3), 233–242.
go back to reference Dardennes, R. M., Al Anbar, N. N., Prado-Netto, A., Kaye, K., Contejean, Y., & Al Anbar, N. N. (2011). Treating the cause of illness rather than the symptoms: Parental causal beliefs and treatment choices in autism spectrum disorder. Research in Developmental Disabilities, 32(3), 1137–1146. doi: 10.​1016/​j.​ridd.​2011.​01.​010. CrossRefPubMed Dardennes, R. M., Al Anbar, N. N., Prado-Netto, A., Kaye, K., Contejean, Y., & Al Anbar, N. N. (2011). Treating the cause of illness rather than the symptoms: Parental causal beliefs and treatment choices in autism spectrum disorder. Research in Developmental Disabilities, 32(3), 1137–1146. doi: 10.​1016/​j.​ridd.​2011.​01.​010. CrossRefPubMed
go back to reference DeStafano, F., & Chen, R. T. (2001). Autism and measles–mumps–rubella vaccination: Controversy laid to rest? CNS Drugs, 15(11), 831–837. CrossRef DeStafano, F., & Chen, R. T. (2001). Autism and measles–mumps–rubella vaccination: Controversy laid to rest? CNS Drugs, 15(11), 831–837. CrossRef
go back to reference Filipek, P. A., Accardo, P. J., Baranek, G. T., Cook, E. H., Dawson, G., Gordon, B., et al. (1999). The screening and diagnosis of autistic spectrum disorders. Journal of Autism and Developmental Disorders, 29(6), 439–484. Filipek, P. A., Accardo, P. J., Baranek, G. T., Cook, E. H., Dawson, G., Gordon, B., et al. (1999). The screening and diagnosis of autistic spectrum disorders. Journal of Autism and Developmental Disorders, 29(6), 439–484.
go back to reference Fischbach, G. D., & Lord, C. (2010). The Simons Simplex Collection: A resource for identification of autism genetic risk factors. Neuron, 68(2), 192–195. CrossRefPubMed Fischbach, G. D., & Lord, C. (2010). The Simons Simplex Collection: A resource for identification of autism genetic risk factors. Neuron, 68(2), 192–195. CrossRefPubMed
go back to reference Fombonne, E., & Chakrabarti, S. (2001). No evidence for a new variant of measles–mumps–rubella-induced autism. Pediatrics, 8(4), 991–998. Fombonne, E., & Chakrabarti, S. (2001). No evidence for a new variant of measles–mumps–rubella-induced autism. Pediatrics, 8(4), 991–998.
go back to reference Le Couteur, A., Lord, C., & Rutter, M. (2003). The autism diagnostic interview-revised (ADI-R). Los Angeles, CA: Western Psychological Services. Le Couteur, A., Lord, C., & Rutter, M. (2003). The autism diagnostic interview-revised (ADI-R). Los Angeles, CA: Western Psychological Services.
go back to reference Levy, S. E., & Hyman, S. L. (2003). Use of complementary and alternative treatments for children with autistic spectrum disorders is increasing. Pediatric Annals, 32(10), 685–691. CrossRefPubMed Levy, S. E., & Hyman, S. L. (2003). Use of complementary and alternative treatments for children with autistic spectrum disorders is increasing. Pediatric Annals, 32(10), 685–691. CrossRefPubMed
go back to reference Madsen, K. M., Hviid, A., Vestergaard, M., Schendel, D., Wohlfahrt, J., Thorsen, P., et al. (2002). A population-based study of measles, mumps, and rubella vaccination and autism. The New England Journal of Medicine, 347(19), 1477–1482. CrossRefPubMed Madsen, K. M., Hviid, A., Vestergaard, M., Schendel, D., Wohlfahrt, J., Thorsen, P., et al. (2002). A population-based study of measles, mumps, and rubella vaccination and autism. The New England Journal of Medicine, 347(19), 1477–1482. CrossRefPubMed
go back to reference Molloy, C. A., Morrow, A. L., Meinzen-Derr, J., Dawson, G., Bernier, R., Dunn, M., et al. (2006). Familial autoimmune thyroid disease as a risk factor for regression in children with autism spectrum disorder: A CPEA study. Journal of Autism and Developmental Disorders, 36(3), 317–324. Molloy, C. A., Morrow, A. L., Meinzen-Derr, J., Dawson, G., Bernier, R., Dunn, M., et al. (2006). Familial autoimmune thyroid disease as a risk factor for regression in children with autism spectrum disorder: A CPEA study. Journal of Autism and Developmental Disorders, 36(3), 317–324.
go back to reference Nordahl, C. W., Lange, N., Li, D. D., Barnett, L. A., Lee, A., Buonocore, M. H., et al. (2011). Brain enlargement is associated with regression in preschool-age boys with autism spectrum disorders. Proceedings of the National Academy of Sciences of the Unites States of America, 108(50), 20195–20200. CrossRef Nordahl, C. W., Lange, N., Li, D. D., Barnett, L. A., Lee, A., Buonocore, M. H., et al. (2011). Brain enlargement is associated with regression in preschool-age boys with autism spectrum disorders. Proceedings of the National Academy of Sciences of the Unites States of America, 108(50), 20195–20200. CrossRef
go back to reference Offit, P. A. (2008). Autism’s false prophets. New York, NY: Columbia University Press. Offit, P. A. (2008). Autism’s false prophets. New York, NY: Columbia University Press.
go back to reference Ozonoff, S., Iosif, A. M., Baguio, F., Cook, I. C., Hill, M. M., Hutman, T., et al. (2010). A prospective study of the emergence of early behavioral signs of autism. Journal of the American Academy of Child and Adolescent Psychiatry, 49(3), 256–266. PubMedCentralPubMed Ozonoff, S., Iosif, A. M., Baguio, F., Cook, I. C., Hill, M. M., Hutman, T., et al. (2010). A prospective study of the emergence of early behavioral signs of autism. Journal of the American Academy of Child and Adolescent Psychiatry, 49(3), 256–266. PubMedCentralPubMed
go back to reference Parker, S. K., Schwartz, B., Todd, J., & Pickering, L. K. (2004). Thimerosal-containing vaccines and autistic spectrum disorder: A critical review of published original data. Pediatrics, 114(3), 793–804. CrossRefPubMed Parker, S. K., Schwartz, B., Todd, J., & Pickering, L. K. (2004). Thimerosal-containing vaccines and autistic spectrum disorder: A critical review of published original data. Pediatrics, 114(3), 793–804. CrossRefPubMed
go back to reference Parr, J. R., Le Couteur, A., Baird, G., Rutter, M., Pickles, A., Fombonne, E., et al. (2011). Early developmental regression in autism spectrum disorder: Evidence from an international multiplex sample. Journal of Autism and Developmental Disorders, 41(3), 332–340. doi: 10.​1007/​s10803-010-1055-2. CrossRefPubMed Parr, J. R., Le Couteur, A., Baird, G., Rutter, M., Pickles, A., Fombonne, E., et al. (2011). Early developmental regression in autism spectrum disorder: Evidence from an international multiplex sample. Journal of Autism and Developmental Disorders, 41(3), 332–340. doi: 10.​1007/​s10803-010-1055-2. CrossRefPubMed
go back to reference Rapin, I. (2006). Language heterogeneity and regression in the autism spectrum disorders—Overlaps with other language regression syndromes. Clinical Neuroscience Research, 6, 209–218. Rapin, I. (2006). Language heterogeneity and regression in the autism spectrum disorders—Overlaps with other language regression syndromes. Clinical Neuroscience Research, 6, 209–218.
go back to reference Richler, J., Luyster, R., Risi, S., Hsu, W.-L., Dawson, G., Bernier, R., et al. (2006). Is there a ‘regressive phenotype’ of autism spectrum disorder associated with the Measles–Mumps–Rubella vaccine? A CPEA study. Journal of Autism and Developmental Disorders, 36(3), 299–316. doi: 10.​1007/​s10803-005-0070-1. CrossRefPubMed Richler, J., Luyster, R., Risi, S., Hsu, W.-L., Dawson, G., Bernier, R., et al. (2006). Is there a ‘regressive phenotype’ of autism spectrum disorder associated with the Measles–Mumps–Rubella vaccine? A CPEA study. Journal of Autism and Developmental Disorders, 36(3), 299–316. doi: 10.​1007/​s10803-005-0070-1. CrossRefPubMed
go back to reference Rosenberg, R. E., Law, J. K., Anderson, C., Samango-Sprouse, C., & Law, P. A. (2013). Survey of vaccine beliefs and practices among families affected by autism spectrum disorders. Clinical Pediatrics, 52(9), 871–874. CrossRefPubMed Rosenberg, R. E., Law, J. K., Anderson, C., Samango-Sprouse, C., & Law, P. A. (2013). Survey of vaccine beliefs and practices among families affected by autism spectrum disorders. Clinical Pediatrics, 52(9), 871–874. CrossRefPubMed
go back to reference Selkirk, C. G., Veach, P. M., Lian, F., Schimmenti, L., & LeRoy, B. S. (2009). Parents’ perceptions of autism spectrum disorder etiology and recurrence risk and effects of their perceptions on family planning: Recommendations for genetic counselors. Journal of Genetic Counseling, 18(5), 507–519. doi: 10.​1007/​s10897-009-9233-0. CrossRefPubMed Selkirk, C. G., Veach, P. M., Lian, F., Schimmenti, L., & LeRoy, B. S. (2009). Parents’ perceptions of autism spectrum disorder etiology and recurrence risk and effects of their perceptions on family planning: Recommendations for genetic counselors. Journal of Genetic Counseling, 18(5), 507–519. doi: 10.​1007/​s10897-009-9233-0. CrossRefPubMed
go back to reference Shumway, S., Thurm, A., Swedo, S. E., Deprey, L., Barnett, L. A., Amaral, D. G., et al. (2011). Brief report: Symptom onset patterns and functional outcomes in young children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 41(12), 1727–1732. doi: 10.​1007/​s10803-011-1203-3. CrossRefPubMedCentralPubMed Shumway, S., Thurm, A., Swedo, S. E., Deprey, L., Barnett, L. A., Amaral, D. G., et al. (2011). Brief report: Symptom onset patterns and functional outcomes in young children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 41(12), 1727–1732. doi: 10.​1007/​s10803-011-1203-3. CrossRefPubMedCentralPubMed
go back to reference Taylor, B., Miller, E., Lingam, R., Andrews, N., Simmons, A., & Stowe, J. (2002). Measles, mumps, and rubella vaccination and bowel problems or developmental regression in children with autism: Population study. British Medical Journal (BMJ), 324(7334), 393–396. doi: 10.​1136/​bmj.​324.​7334.​393. CrossRef Taylor, B., Miller, E., Lingam, R., Andrews, N., Simmons, A., & Stowe, J. (2002). Measles, mumps, and rubella vaccination and bowel problems or developmental regression in children with autism: Population study. British Medical Journal (BMJ), 324(7334), 393–396. doi: 10.​1136/​bmj.​324.​7334.​393. CrossRef
go back to reference Weinman, J., Petrie, K. J., Sharpe, N., & Walker, S. (2000). Causal attributions in patients and spouses following first-time myocardial infarction and subsequent lifestyle changes. British Journal of Health Psychology, 5(Part3), 263–273. doi: 10.​1348/​135910700168900. CrossRef Weinman, J., Petrie, K. J., Sharpe, N., & Walker, S. (2000). Causal attributions in patients and spouses following first-time myocardial infarction and subsequent lifestyle changes. British Journal of Health Psychology, 5(Part3), 263–273. doi: 10.​1348/​135910700168900. CrossRef
go back to reference Zhang, Y., Xu, Q., Liu, J., Li, S. C., & Xu, X. (2012). Risk factors for autistic regression: Results of an ambispective cohort study. Journal of Child Neurology, 27(8), 975–981. Zhang, Y., Xu, Q., Liu, J., Li, S. C., & Xu, X. (2012). Risk factors for autistic regression: Results of an ambispective cohort study. Journal of Child Neurology, 27(8), 975–981.
Metagegevens
Titel
Emergence of Autism Spectrum Disorder in Children from Simplex Families: Relations to Parental Perceptions of Etiology
Auteurs
Robin P. Goin-Kochel
Sarah S. Mire
Allison G. Dempsey
Publicatiedatum
01-05-2015
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 5/2015
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-014-2310-8

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