EEG Spectral Features in Sleep of Autism Spectrum Disorders in Children with Tuberous Sclerosis Complex
- 06-12-2019
- Original Paper
Gepubliceerd in:
- Auteurs
- Ian A. Cook
- Andrew C. Wilson
- Jurriaan M. Peters
- Monisha N. Goyal
- E. Martina Bebin
- Hope Northrup
- Darcy Krueger
- Andrew F. Leuchter
- Mustafa Sahin
- the TACERN Study Group
- Gepubliceerd in
- Journal of Autism and Developmental Disorders | Uitgave 3/2020
Abstract
Tuberous sclerosis complex (TSC) is a multisystem disorder with increased prevalence of autism spectrum disorders (ASDs). This project aimed to characterize the autism phenotype of TSC and identify biomarkers of risk for ASD. Because abnormalities of EEG during sleep are tied to neurodevelopment in children, we compared electroencephalographic (EEG) measures during Stage II sleep in TSC children who either did (ASD+) or did not (ASD−) exhibit symptoms of ASD over 36-month follow up. Relative alpha band power was significantly elevated in the ASD+ group at 24 months of age with smaller differences at younger ages, suggesting this may arise from differences in brain development. These findings suggest that EEG features could enhance the detection of risk for ASD.
- Titel
- EEG Spectral Features in Sleep of Autism Spectrum Disorders in Children with Tuberous Sclerosis Complex
- Auteurs
-
Ian A. Cook
Andrew C. Wilson
Jurriaan M. Peters
Monisha N. Goyal
E. Martina Bebin
Hope Northrup
Darcy Krueger
Andrew F. Leuchter
Mustafa Sahin
the TACERN Study Group
- Publicatiedatum
- 06-12-2019
- Uitgeverij
- Springer US
- Gepubliceerd in
-
Journal of Autism and Developmental Disorders / Uitgave 3/2020
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432 - DOI
- https://doi.org/10.1007/s10803-019-04326-0
Deze inhoud is alleen zichtbaar als je bent ingelogd en de juiste rechten hebt.
Deze inhoud is alleen zichtbaar als je bent ingelogd en de juiste rechten hebt.